Clinical trials
Shock clinical trials
Below are recruiting shock clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04323371Recruiting
Study testing for heart-shock to reduce future events
This trial studies how to identify different types of “cardiogenic shock,” a serious drop in heart blood flow. It aims to use detailed patient information to guide care and possibly lower the chance of dangerous outcomes.
MilanAges 18–74 - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT04448951Recruiting
Study of immune response in early sepsis or septic shock
This trial looks at how the immune system behaves in the first day after septic shock begins. It may help researchers find better ways to support the body’s immune balance during sepsis, but you must be enrolled very quickly.
Pilsen, Česká RepublikaAges 18 years+ - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT04760977Recruiting
HEMS care for bleeding trauma with low blood pressure
This trial studies how emergency helicopter (HEMS) teams manage trauma patients who have signs of shock from blood loss, especially when bleeding is suspected or ongoing. It may help teams choose the best pre-hospital approach to stabilize you sooner.
AlessandriaAges 18 years+ - NCT04770584Recruiting
Fear and avoidance study in PTSD and healthy volunteers
This study looks at how people with current PTSD—or people without PTSD—respond to fear and avoiding things they might find threatening. It may help researchers understand these patterns and how they differ after trauma.
Houston, TexasAges 18–70 - NCT04774705Recruiting
Noninvasive vagus nerve stimulation for sepsis in the ICU
This study tests whether a noninvasive device that stimulates the vagus nerve can help adults with sepsis in the intensive care unit. Researchers want to see if adding this treatment improves outcomes compared with standard ICU care.
GarchesAges 18 years+ - NCT04910841Recruiting
Testing a glucose-monitoring device in septic shock ICU
This trial checks whether a continuous glucose monitoring system (“CGM GUARDIAN 2”) can be used safely and effectively for people in the ICU who have septic shock and high blood sugar. It may help the medical team track blood sugar more easily while you receive insulin.
NiceAges 18 years+ - NCT04920565Recruiting
Hemoperfusion with Polymyxin B for septic shock after heart surgery
This trial studies a blood-filter treatment (hemoperfusion with Polymyxin B) to reduce harmful substances in the blood for people who develop septic shock after heart surgery. It may help by lowering inflammation and improving safety, but it also requires meeting specific signs of severe infection and blood/bleeding conditions.
MoscowAges 18–80 - NCT04931225RecruitingPhase 3
Landiolol for heart-rate and circulation problems in septic shock
This Phase 3 trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can improve blood circulation in adults with septic shock whose heart rate is too fast. Doctors will also check that the medication is safe in this critical-care setting.
ParisAges 18 years+ - NCT04972526Recruiting
Registry for adult patients who get an ultrasound heart scan in ICU
This study is a registry, meaning it collects information from adult patients who—during routine emergency care in the ICU—receive a focused ultrasound of the heart (a test called TEE). It helps doctors learn how this test is used and what outcomes follow, with no extra treatment required.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05225402Recruiting
Testing blood-flow measurements in ICU shock patients
This trial studies how blood flow and organ “perfusion” look in ICU patients who are struggling with infection and low blood pressure. It may help doctors better measure and manage shock by comparing hemodynamic readings during standard treatment.
Hvidovre, CopenhagenAges 18 years+ - NCT05226637Recruiting
Shockwave plus botox-like treatment versus standard care for arm spasticity
This study tests whether adding shockwave treatment to botulinum toxin type A (a botox-like injection) improves outcomes for people with stiff, tight upper-arm muscles after brain injury, stroke, or cerebral palsy. It also compares this to standard botulinum toxin care alone.
Edmonton, AlbertaAges 18–99 - NCT05336357Recruiting
Non-invasive treatment plan for septic shock
This study tests a non-invasive, goal-based treatment approach for people with septic shock—an emergency condition caused by severe infection. It may help by using blood-pressure and circulation targets to guide care without more invasive procedures.
São PauloAges 18 years+ - NCT05442710RecruitingPhase 2
Immune cell treatment for recovery from severe septic shock
This trial tests an immune-cell treatment given outside the body to help people recover from septic shock, a life-threatening reaction to infection. It aims to improve survival and organ recovery in patients who are still very ill despite standard care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT05449834RecruitingPhase 3
Testing early fibrinogen treatment after serious trauma bleeding
This Phase 3 study tests whether giving fibrinogen early can improve outcomes for adults with serious trauma who are actively bleeding. The goal is to help blood clotting work better sooner and potentially reduce complications from uncontrolled bleeding.
Newcastle, New South WalesAges 18–100 - NCT05491941Recruiting
Testing ways to improve care for sepsis patients
This trial looks at how to best put proven sepsis care steps into practice in the emergency department. It may help you or other patients receive faster, more consistent treatment for sepsis.
Providence, Rhode IslandAges 18 years+ - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT05634109RecruitingPhase 3
Whole blood to treat adults with severe bleeding trauma
This trial compares giving whole blood versus standard care in adults with severe trauma and dangerous blood loss (hemorrhagic shock). The goal is to see if whole blood helps stabilize patients faster and improves outcomes after major bleeding.
Cali, Valle del Cauca DepartmentAges 18 years+ - NCT05638581RecruitingPhase 3
Compare low-titer type O whole blood for trauma bleeding
This study tests whether giving low-titer type O whole blood (or related blood products) works better for treating serious bleeding after a traumatic injury. It’s for adults who start blood transfusions right away under a massive bleeding plan.
Birmingham, AlabamaAges 15 years+ - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05725837RecruitingPhase 2
Paroxetine for circulation problems in early septic shock
This Phase 2 trial tests whether paroxetine can improve heart and blood-flow function in adults with septic shock that started within the last 48 hours. If you’re eligible, you may be asked to take the study medicine soon after diagnosis to see if it helps your cardiovascular function.
Colatina, Espírito SantoAges 18 years+ - NCT05761522Recruiting
Testing norepinephrine for blood pressure in septic shock
This trial studies how norepinephrine affects the heart and circulation in adults with septic shock whose blood pressure stays low after the first day. It may help doctors better choose and adjust medicines to support blood pressure and organ function.
ReimsAges 18 years+
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Common questions
- Are there clinical trials for shock?
- Yes. Clin2 currently lists 328 recruiting shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.