Clinical trials
Stress Response clinical trials
Below are recruiting stress response clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06348472Recruiting
Biomarkers and PTSD psychotherapy response
This study is looking at whether certain biomarkers in your blood (related to inflammation and the oxytocin system) can predict how well you respond to trauma-focused psychotherapy. It may help find better ways to personalize PTSD treatment.
Hod HaSharonAges 18–80 - NCT06582680RecruitingPhase 4
Aging, beta-blockers, and body temperature control
This study looks at how aging affects the body's ability to control temperature, especially for people taking beta-blockers (medicines for heart conditions). It may help researchers understand how to better manage heat-related risks in older adults.
Dallas, TexasAges 65 years+ - NCT06263452RecruitingPhase 4
Beta-blockers and stress response study
This trial tests how beta-blockers affect your body's reaction to stress. You'll take a beta-blocker or placebo and then do a stress task, so researchers can measure inflammation and other responses.
Chapel Hill, North CarolinaAges 18–30 - NCT06907225Recruiting
How heat affects soldiers during training
This study measures how your body responds to heat stress during physically demanding military training events. The results may help prevent heat-related injuries in service members.
Fort Novosel, AlabamaAges 18 years+ - NCT06860724Recruiting
Stress and blood vessel health study for adults 18-55
This study looks at how daily stress affects blood vessel function in healthy adults and those with depression. It aims to find links between emotions and physical health.
Newark, DelawareAges 18–55 - NCT06603064Recruiting
Brain stimulation study on stress and emotions
This study uses brain scans to understand how your brain responds to stress. You will complete tasks and answer questions while undergoing an MRI to help researchers learn more about emotional responses.
Pittsburgh, PennsylvaniaAges 30–50 - NCT06973902Recruiting
A study on heart pump therapy and stress echo for advanced heart failure
This trial tests how well a heart stress ultrasound (dobutamine echo) can predict if you will get better from a special heart device called cardiac contractility modulation (CCM). CCM is a pacemaker-like implant for people with advanced heart failure who still have symptoms even with the best medicines. The study will help doctors know which patients benefit the most from this device.
Marcianise, CampaniaAges 18 years+ - NCT07781670Recruiting
Brain and body responses to physical and emotional stress
This study looks at how your brain and body (heart rate, etc.) respond to sudden physical and emotional stress. You will do tasks like placing your hand in cold water or viewing emotional images while we record your brain activity with EEG. The results may help understand how stress affects health.
Pavia, LombardyAges 18 years+ - NCT07321028Enrolling by invitationEarly Phase 1
Study of freezing methods on human cell samples
This study tests different freezing methods on human cell samples to see which work best. It does not involve human volunteers, only donated cells that have been de-identified.
New York, New YorkAges Any age - NCT07431658Enrolling by invitation
Diet and stress effects on omalizumab response in chronic hives
This study looks at how diet and oxidative stress (a type of cell damage) affect the severity of chronic hives and how well patients respond to the medication omalizumab (Xolair). It may help find ways to improve treatment by understanding these factors.
IstanbulAges 18–65 - NCT07250555Recruiting
Basketball fatigue and energy study
This study looks at how basketball players' bodies produce energy and how tired they get during a game. It may help find ways to improve performance and recovery.
Trikala, ThessalyAges 18–30 - NCT06279598Recruiting
Predicting PTSD treatment success and handling non-response (PT-STRESS)
This study looks at how well PTSD treatments work and what happens when they don't. It tests ways to predict if a treatment will be successful for you.
DeventerAges 18–65 - NCT05915013RecruitingPhase 1
Brain-targeting study of ketamine response in treatment-resistant depression
This early-stage study looks at how parts of brain cells respond to ketamine in people with depression who have not improved with usual antidepressants. It may help researchers find why ketamine works for some people and not others, and who might benefit.
New Haven, ConnecticutAges 18–60 - NCT05545865Recruiting
Test how grape-based drinks affect blood flow response
This study tests whether a grape product (“Chardonnay Marc”) can change how your blood vessels respond to stress, measured with a finger sensor. It may help researchers understand how diet influences circulation in people with a low baseline blood-flow response.
Davis, CaliforniaAges 30–50 - NCT06582225Recruiting
Online CBT for OCD in children with autism
This study tests if internet-based cognitive behavioral therapy (CBT) can help children and teens with autism who also have OCD. Treatment is delivered online with parent support, making it easier to access care at home.
Lund, Skåne CountyAges 7–17 - NCT05327699RecruitingEarly Phase 1
Ketamine study for depression with reduced pleasure
This early-phase study tests whether ketamine can help people with major depression who have trouble feeling pleasure. It also studies how the brain may change in response to stress, to better understand who might respond to treatment.
Atlanta, GeorgiaAges 18–65 - NCT07781592Enrolling by invitation
Exercise intensity and heat response in young people
This study looks at how exercise intensity affects body temperature in healthy children and young adults. Participants will exercise and may need to swallow a small pill that measures body temperature from inside.
Ottawa, OntarioAges 9–25 - NCT06718907Recruiting
Stress relief for pregnant women
This study tests a program to help pregnant women manage stress. It is for women who are at least 24 weeks pregnant and between the ages of 21 and 37.
Davie, FloridaAges 21–37 - NCT06088303Recruiting
Improving PTSD treatment through better communication
This study tests if improving how you talk with your doctor can make PTSD treatment work better. You can join if you have PTSD and have been on stable medications for at least 4 weeks.
Boston, MassachusettsAges 18 years+ - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT06505980Recruiting
Parent training for child behavior concerns
This trial tests a brief telehealth program to help parents manage their child's challenging behaviors. It may help if your child has elevated behavior issues and you can participate online.
Aurora, ColoradoAges 3–5 - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT06823024Enrolling by invitation
Using speech patterns to predict treatment response in depression, PTSD, or bipolar disorder
This study tests if a computer algorithm can analyze your speech to predict how well you will respond to treatments like TMS or Spravato. It aims to create a simple tool that helps doctors choose the right treatment for you.
Sunnyvale, CaliforniaAges 18–68
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Common questions
- Are there clinical trials for stress response?
- Yes. Clin2 currently lists 51 recruiting stress response studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress response trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress response trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.