Clinical trials
Stress Response clinical trials
Below are recruiting stress response clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT07568938Recruiting
Anesthesia types and stress response in weight-loss surgery
This study compares two anesthesia methods—inhaled gas (desflurane) versus IV medication (TIVA)—during weight-loss surgery to see how each affects your body's stress response and recovery. The goal is to understand which approach may be safer and more comfortable for patients having bariatric surgery.
AthensAges 18–65 - NCT06263452RecruitingPhase 4
Beta-blockers and stress response study
This trial tests how beta-blockers affect your body's reaction to stress. You'll take a beta-blocker or placebo and then do a stress task, so researchers can measure inflammation and other responses.
Chapel Hill, North CarolinaAges 18–30 - NCT06348472Recruiting
Biomarkers and PTSD psychotherapy response
This study is looking at whether certain biomarkers in your blood (related to inflammation and the oxytocin system) can predict how well you respond to trauma-focused psychotherapy. It may help find better ways to personalize PTSD treatment.
Hod HaSharonAges 18–80 - NCT06582680RecruitingPhase 4
Aging, beta-blockers, and body temperature control
This study looks at how aging affects the body's ability to control temperature, especially for people taking beta-blockers (medicines for heart conditions). It may help researchers understand how to better manage heat-related risks in older adults.
Dallas, TexasAges 65 years+ - NCT06603064Recruiting
Brain stimulation study on stress and emotions
This study uses brain scans to understand how your brain responds to stress. You will complete tasks and answer questions while undergoing an MRI to help researchers learn more about emotional responses.
Pittsburgh, PennsylvaniaAges 30–50 - NCT06860724Recruiting
Stress and blood vessel health study for adults 18-55
This study looks at how daily stress affects blood vessel function in healthy adults and those with depression. It aims to find links between emotions and physical health.
Newark, DelawareAges 18–55 - NCT06907225Recruiting
How heat affects soldiers during training
This study measures how your body responds to heat stress during physically demanding military training events. The results may help prevent heat-related injuries in service members.
Fort Novosel, AlabamaAges 18 years+ - NCT06973902Recruiting
A study on heart pump therapy and stress echo for advanced heart failure
This trial tests how well a heart stress ultrasound (dobutamine echo) can predict if you will get better from a special heart device called cardiac contractility modulation (CCM). CCM is a pacemaker-like implant for people with advanced heart failure who still have symptoms even with the best medicines. The study will help doctors know which patients benefit the most from this device.
Marcianise, CampaniaAges 18 years+ - NCT07321028Enrolling by invitationEarly Phase 1
Study of freezing methods on human cell samples
This study tests different freezing methods on human cell samples to see which work best. It does not involve human volunteers, only donated cells that have been de-identified.
New York, New YorkAges Any age - NCT07250555Recruiting
Basketball fatigue and energy study
This study looks at how basketball players' bodies produce energy and how tired they get during a game. It may help find ways to improve performance and recovery.
Trikala, ThessalyAges 18–30 - NCT06513611Recruiting
Immune and hormone markers in acute coronary syndrome prognosis
This trial looks at how your body's immune system, hormones, and inflammation affect recovery after a heart attack or unstable angina. It may help doctors better predict outcomes for people with acute coronary syndrome.
Buenos AiresAges 21 years+ - NCT07431658Enrolling by invitation
Diet and stress effects on omalizumab response in chronic hives
This study looks at how diet and oxidative stress (a type of cell damage) affect the severity of chronic hives and how well patients respond to the medication omalizumab (Xolair). It may help find ways to improve treatment by understanding these factors.
IstanbulAges 18–65 - NCT06279598Recruiting
Predicting PTSD treatment success and handling non-response (PT-STRESS)
This study looks at how well PTSD treatments work and what happens when they don't. It tests ways to predict if a treatment will be successful for you.
DeventerAges 18–65 - NCT04152993RecruitingEarly Phase 1
Brain stimulator study for chronic, hard-to-treat PTSD
This early-phase study tests a responsive brain stimulation device to help people with chronic PTSD who have not improved with standard treatments. You would be closely followed for years, with regular assessments and device setting changes to see if symptoms improve.
Los Angeles, CaliforniaAges 25–60 - NCT05545865Recruiting
Test how grape-based drinks affect blood flow response
This study tests whether a grape product (“Chardonnay Marc”) can change how your blood vessels respond to stress, measured with a finger sensor. It may help researchers understand how diet influences circulation in people with a low baseline blood-flow response.
Davis, CaliforniaAges 30–50 - NCT05915013RecruitingPhase 1
Brain-targeting study of ketamine response in treatment-resistant depression
This early-stage study looks at how parts of brain cells respond to ketamine in people with depression who have not improved with usual antidepressants. It may help researchers find why ketamine works for some people and not others, and who might benefit.
New Haven, ConnecticutAges 18–60 - NCT05213000Recruiting
Exercise program study to boost vaccine immune response
This study looks at whether regular light-to-moderate exercise around the time of getting an mRNA COVID-19 vaccine can improve your immune response. It may help researchers understand how stress and exercise affect how well vaccines work.
Ames, IowaAges 18–64 - NCT05327699RecruitingEarly Phase 1
Ketamine study for depression with reduced pleasure
This early-phase study tests whether ketamine can help people with major depression who have trouble feeling pleasure. It also studies how the brain may change in response to stress, to better understand who might respond to treatment.
Atlanta, GeorgiaAges 18–65 - NCT06582225Recruiting
Online CBT for OCD in children with autism
This study tests if internet-based cognitive behavioral therapy (CBT) can help children and teens with autism who also have OCD. Treatment is delivered online with parent support, making it easier to access care at home.
Lund, Skåne CountyAges 7–17 - NCT06718907Recruiting
Stress relief for pregnant women
This study tests a program to help pregnant women manage stress. It is for women who are at least 24 weeks pregnant and between the ages of 21 and 37.
Davie, FloridaAges 21–37 - NCT06088303Recruiting
Improving PTSD treatment through better communication
This study tests if improving how you talk with your doctor can make PTSD treatment work better. You can join if you have PTSD and have been on stable medications for at least 4 weeks.
Boston, MassachusettsAges 18 years+ - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT06505980Recruiting
Parent training for child behavior concerns
This trial tests a brief telehealth program to help parents manage their child's challenging behaviors. It may help if your child has elevated behavior issues and you can participate online.
Aurora, ColoradoAges 3–5
Hear when a new Stress Response trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for stress response?
- Yes. Clin2 currently lists 53 recruiting stress response studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress response trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress response trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.