Clinical trials
Stroke Prevention clinical trials
Below are recruiting stroke prevention clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT06324188Recruiting
Early ablation for afib to prevent stroke in high-risk patients
This trial tests whether an early procedure (catheter ablation) for atrial fibrillation (AF) can prevent strokes in people with a high risk of stroke. The goal is to see if this treatment is safer and more effective than standard care for patients with other health conditions.
Multiple LocationsAges 18 years+ - NCT06949319Recruiting
Stroke Risk and Blood Clots in New Atrial Fibrillation
This study looks at stroke risk and blood clotting in people who have just been diagnosed with atrial fibrillation (AFib) that is not caused by a heart valve problem, and who have not yet taken blood thinners. It aims to better understand how blood clots form in this condition.
Esbjerg, Region SyddanmarkAges 18 years+ - NCT05807269Recruiting
Stroke prevention and rehabilitation program in Uganda
This program focuses on helping people who have had a stroke, or who have stroke risk factors, through prevention and rehabilitation support. It may help you improve recovery and lower the chance of another stroke.
HoimaAges 13 years+ - NCT07045233Enrolling by invitation
Using a brain protection device during TAVR to prevent stroke
This study tests if a special device placed during transcatheter aortic valve replacement (TAVR) can help prevent stroke. It is for adults with severe aortic stenosis who are already scheduled for TAVR.
BeijingAges 18 years+ - NCT04948749Recruiting
Stenting plus medication to prevent stroke from narrowed brain arteries
This trial tests whether placing a stent in a severely narrowed brain artery, along with aggressive medication, can prevent another stroke better than medication alone. It is for people who had a mild stroke within the last 30 days due to a 70-99% blockage in a major brain artery.
Beijing, Beijing MunicipalityAges 18–85 - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Rockford, IllinoisAges 18 years+ - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT05476913Recruiting
Preventing blood clots after stroke with a leg device
This study checks whether using a special device on the legs can help prevent dangerous blood clots after an acute stroke. You may be eligible if you recently had a stroke and you’re not able to get up and walk to the toilet without help.
Bury St Edmunds, SuffolkAges 18 years+ - NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT05545605Recruiting
Sodium oligomannate to prevent thinking problems after stroke
This trial tests whether sodium oligomannate can help prevent or lessen memory and thinking problems that can happen after a first stroke. It may help people who are recently hospitalized for ischemic stroke and have mild cognitive decline risk.
Guangzhou, BaiyunAges 18–80 - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT04205279Recruiting
Balance training to help prevent falls
This study tests a reactive balance training program to reduce fall risk. It may help you improve how your balance reacts when you are pushed or lose stability.
Chicago, IllinoisAges 18–90 - NCT07687706RecruitingPhase 3
Tegoprazan to prevent stomach problems after stroke
This study tests a stomach-protecting medicine called tegoprazan for people who have had a stroke and are starting antiplatelet therapy. It aims to prevent stomach complications like ulcers or bleeding.
Busan, BusanAges 19 years+ - NCT05995600RecruitingPhase 4
Clopidogrel vs warfarin to prevent a second APS stroke
This study compares two types of blood thinners — clopidogrel (an antiplatelet) and warfarin — to prevent another stroke in people with antiphospholipid syndrome (APS). It aims to find which medicine works better for people who have already had a stroke related to APS.
AnyangAges 19 years+ - NCT06649240Recruiting
Best LDL cholesterol goal after small vessel stroke
This trial is testing the best target for 'bad' cholesterol (LDL) after a type of stroke caused by a small blocked vessel. You would be in one of two groups to see which LDL level helps prevent another stroke the most.
AnsanAges 19 years+ - NCT06857487RecruitingPhase 1/Phase 2
Testing an herb formula to prevent early stroke worsening
This study tests a traditional Chinese herb formula called Qingre Huatan to see if it can stop stroke symptoms from getting worse in the first few days. It is for people who have had an ischemic stroke within the last 48 hours and are at high risk for early decline.
Beijing, Beijing MunicipalityAges 18–80 - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06714097Recruiting
Digital twin technology for stroke and related conditions
This trial tests a digital twin system to help prevent a second stroke or brain bleed in people with stroke, Moyamoya disease, or cerebral amyloid angiopathy. The system uses your medical data to create a virtual copy of you, which doctors can use to plan your care.
Milan, MichiganAges 18 years+ - NCT04559243Recruiting
Left atrial appendage closure to prevent stroke in AF
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Jinan, ShandongAges 18 years+ - NCT06899711Recruiting
A helmet after skull surgery to prevent sunken flap
This study tests whether wearing a custom-made external helmet after a large skull removal surgery can prevent the skin from sinking in. If you've had this surgery in the last two weeks and are being treated at a Johns Hopkins hospital, you may be eligible.
Baltimore, MarylandAges 18 years+ - NCT06023212RecruitingPhase 1/Phase 2
Tranexamic acid to prevent bleeding in spine surgery for lung cancer
This trial tests if a medicine called tranexamic acid can help reduce bleeding during surgery for lung cancer that has spread to the spine. It may be an option if you have a single tumor in your spine and are having separation surgery.
Hangzhou, ZhejiangAges 10–80
Hear when a new Stroke Prevention trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for stroke prevention?
- Yes. Clin2 currently lists 50 recruiting stroke prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stroke prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stroke prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.