Clinical trials · Chicago, IL
Stroke clinical trials in Chicago
We’re tracking 53 recruiting stroke studies with a site in or near Chicago — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT06870812Recruiting
Quick removal of brain bleed clot study
This trial tests a rapid procedure to remove a blood clot in the brain after a specific type of stroke. It might help people with a moderate-sized bleed in the front part of the brain if treatment can start within 24 hours.
Chicago, IllinoisAges 18–70 - NCT03401762Recruiting
Wearable device training for stroke arm coordination
This trial tests a wearable device and training task to help improve how stroke-affected arm muscles work together. It may help reduce unwanted “extra muscle effort” and improve control in people with recent or long-term stroke.
Chicago, IllinoisAges 21 years+ - NCT06400186Recruiting
Walking training to improve balance after stroke
This trial tests a new walking training method designed to help you improve your balance after a stroke. It's for people who have had a stroke more than 6 months ago and can walk a short distance, with or without a cane or simple ankle brace.
Chicago, IllinoisAges 18–80 - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Chicago, IllinoisAges 18–80 - NCT07806097Recruiting
Self-directed arm gaming during stroke rehab
This trial tests whether playing arm-focused video games on your own helps improve arm movement while you're in the hospital for stroke rehabilitation. You would play games that involve moving your arm and hand, and the goal is to see if this makes your recovery better.
Chicago, IllinoisAges 18 years+ - NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Chicago, IllinoisAges 18–85 - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Chicago, IllinoisAges 18 years+ - NCT04205279Recruiting
Balance training to help prevent falls
This study tests a reactive balance training program to reduce fall risk. It may help you improve how your balance reacts when you are pushed or lose stability.
Chicago, IllinoisAges 18–90 - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Chicago, IllinoisAges 18–70 - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Chicago, IllinoisAges 18 years+ - NCT06127602Recruiting
Electrical stimulation plus walking for stroke recovery
This study tests whether adding a type of electrical stimulation to leg muscles during walking can improve walking ability for people who are at least 6 months past a stroke. If you have weakness on one side and can walk on a treadmill with some help, you may be able to join.
Chicago, IllinoisAges 18–90 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Chicago, IllinoisAges 18 years+ - NCT04219670Recruiting
Using sensors to study stroke recovery in hospital and community
This study uses sensor recordings to learn how stroke recovery happens over time, including for people in the hospital and those living in the community. Your results may help improve future monitoring and rehabilitation after stroke.
Chicago, IllinoisAges 18 years+ - NCT06234124Recruiting
A shoe to improve walking after stroke
This study tests a special shoe that changes friction to help improve walking for people who have had a stroke. It lasts 6 months and involves daily exercises at home.
Chicago, IllinoisAges 18 years+ - NCT04312269Recruiting
Brain stimulation plus memory practice to improve stroke arm recovery
This trial tests whether a combined therapy—MyoCI plus memory “reactivation”—can improve arm movement recovery after stroke. It’s meant for people with ongoing arm weakness at least 6 months after their first stroke.
Chicago, IllinoisAges 21–100 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Chicago, IllinoisAges 1–120 - NCT06386874Recruiting
Magnetic field therapy for arm recovery after stroke
This study tests a new magnetic device applied to the head to help improve arm function after a stroke. You will use the device while doing exercises, and a caregiver will support you with a mobile app and video calls.
Chicago, IllinoisAges 22–80 - NCT06990867RecruitingPhase 2/Phase 3
Improving blood flow recovery after stroke
This trial tests a new approach to restore blood flow in the brain after a stroke. It aims to improve recovery and brain function in people with a blocked large artery.
Chicago, IllinoisAges 18–90 - NCT05167786Recruiting
Electrical spinal cord stimulation for walking after stroke
This trial studies whether a non-surgical electrical treatment to the spinal area can improve walking and leg control after a stroke. It’s for people who have had a single stroke and still need hands-on support to walk.
Chicago, IllinoisAges 18 years+ - NCT05194566Recruiting
Brain stimulation for long-term speech trouble after stroke
This study tests whether a form of brain stimulation can improve naming words in people who still have language problems (aphasia) more than 6 months after a stroke. It may help people find and say words more accurately during a naming task.
Chicago, IllinoisAges 18–80 - NCT07652970Recruiting
Home video therapy for severe stroke recovery
This study tests whether a new therapy done at home via video calls can help people with severe, long-lasting stroke regain leg movement and walking ability. If you have trouble walking or moving your leg on one side, this may be an option.
Chicago, IllinoisAges 18–80 - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Evanston, IllinoisAges 18 years+ - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Park Ridge, IllinoisAges 18 years+
Hear when a new Stroke trial opens near Chicago, IL
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Stroke trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting stroke studies listed above.
- Northwestern University · 6 studies
- Shirley Ryan AbilityLab · 5 studies
- University of Chicago Medical Center · 3 studies
- NorthShore University HealthSystem-Evanston Hospital · 2 studies
- Rush University Medical Center · 2 studies
- University of Chicago · 2 studies
- University of Illinois at Chicago · 2 studies
- Advocate Aurora Research Institute
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in Illinois.
Common questions
- Are there stroke clinical trials near Chicago?
- Yes. We're currently tracking 53 recruiting stroke studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.