Clinical trials · California
Stroke clinical trials in California
We’re tracking 64 recruiting stroke studies with a site in California — including Early Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06722755Recruiting
CPAP for Sleep Apnea After Stroke
This study tests whether using a CPAP machine (a device that helps you breathe while sleeping) can improve recovery after a recent stroke or brain bleed. You may join if you had a stroke in the past month and are not already using CPAP.
Downey, CaliforniaAges 18 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Downey, CaliforniaAges 18–80 - NCT06672107Recruiting
Driving simulator training after stroke
This study tests if using a driving simulator can help improve driving skills in veterans who have had a stroke. If you are a veteran who had a stroke at least 3 months ago and are between 40 and 80 years old, this program might help you get back behind the wheel safely.
Sacramento, CaliforniaAges 40–80 - NCT06440707RecruitingPhase 2
Brain stimulation for recent stroke recovery
This trial tests a safe, non-invasive brain stimulation technique called tDCS to help people recover from a recent stroke. It's for people who cannot have the standard clot-removal procedure and who can start treatment within 24 hours of their stroke.
Los Angeles, CaliforniaAges 18 years+ - NCT06402968Recruiting
Clevidipine for treating high blood pressure after a brain bleed
This trial tests a blood pressure medicine called clevidipine given through an IV to people with a brain bleed (intracerebral hemorrhage). The goal is to see if quickly lowering blood pressure helps prevent more bleeding and improve recovery.
Irvine, CaliforniaAges 18–100 - NCT06226493Recruiting
Vagus Nerve Stimulation for Stroke Recovery
This early-stage study tests if putting a mild electrical pulse on the vagus nerve (a nerve in the neck) can help the brain heal after a first-time stroke. It looks for changes in brain activity and certain DNA markers to understand how the treatment works.
Pomona, CaliforniaAges 18–80 - NCT06226805RecruitingPhase 2
Study of BB-031 for acute ischemic stroke
This trial tests a new drug called BB-031 for people who have had a stroke caused by a blocked blood vessel in the brain. The drug may help restore blood flow and reduce damage if given within 24 hours of symptoms starting.
Burlingame, CaliforniaAges 18 years+ - NCT04829071RecruitingEarly Phase 1
Testing brain and movement training after a one-sided stroke
This early research study looks at a way to improve thinking and movement after a stroke that happened more than 6 months ago. It may help people who still have problems using one side of their body to walk and learn new movement skills.
Los Angeles, CaliforniaAges 45–85 - NCT06040255Enrolling by invitationPhase 4
Steroid treatment for focal brain artery inflammation in children
This trial tests whether short-term steroids improve recovery for children who recently had a stroke or mini-stroke caused by inflammation of a brain artery. If you qualify, you would receive steroids and follow-up imaging to see if it helps prevent further damage.
San Francisco, CaliforniaAges 1–18 - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
La Jolla, CaliforniaAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Glendale, CaliforniaAges 18–79 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Santa Barbara, CaliforniaAges 1–120 - NCT03737786Recruiting
Sedation with collateral support for stroke clot removal
This trial tests a specific sedation approach, along with support during the procedure, for people having emergency clot removal (mechanical thrombectomy) for a certain type of acute ischemic stroke. It may help make the procedure safer and more effective by improving how patients are managed during endovascular treatment.
Los Angeles, CaliforniaAges 18–110 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Los Angeles, CaliforniaAges 18 years+ - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
La Jolla, CaliforniaAges 18–70 - NCT02910180Recruiting
Biobank study of genetic and metabolic data in brain blood vessel disease
This study collects genetic and other health information from people with brain blood vessel (cerebrovascular) problems. It aims to help researchers understand causes and patterns that could lead to better care in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT05537753Recruiting
PFO closure device test after recent unexplained stroke
This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
La Jolla, CaliforniaAges 18–60 - NCT07626411RecruitingPhase 3
Blood Thinner Study for Irregular Heartbeat
This study tests a new blood thinner to prevent strokes and blood clots in people with atrial fibrillation (a common heart rhythm problem). You may qualify if you have atrial fibrillation and at least one risk factor for stroke, or if you've never taken a blood thinner before.
Ventura, CaliforniaAges 18 years+ - NCT07528261Recruiting
Support Group for Family Caregivers of Stroke Survivors
This study tests whether a support group using acceptance and commitment therapy (a type of counseling that helps people cope with stress) can reduce caregiver burden and distress. You would meet online with other people caring for stroke survivors.
Alameda, CaliforniaAges 40 years+ - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Fremont, CaliforniaAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Downey, CaliforniaAges 18–80 - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Los Angeles, CaliforniaAges 18 years+
Stroke trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting stroke studies listed above.
- Cedars-Sinai Medical Center · 3 studies
- California Heart Specialists · 2 studies
- Cardiology Associates Medical Group · 2 studies
- Casa Colina Hospital and Centers for Healthcare · 2 studies
- FOMAT - Comprehensive Cardiovascular Care · 2 studies
- Interventional Cardiology Medical Group · 2 studies
- Kaiser Permanente Los Angeles Medical Center · 2 studies
- Mission Cardiovascular Research Institute · 2 studies
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in California?
- Yes. We're currently tracking 64 recruiting stroke studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.