Clinical trials
Structural Heart Disease clinical trials
Below are recruiting structural heart disease clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07514611Recruiting
Weight Loss Guidance for Heart Disease and Obesity
This trial tests whether using a smartphone app to guide weight loss helps people with coronary heart disease (a condition where blood vessels to the heart are narrowed) and obesity lose weight safely. The goal is to see if this personalized digital guidance can improve your health outcomes.
Guangzhou, GuangdongAges 18–65 - NCT07773064Recruiting
Eye imaging for heart disease risk
This study looks at using pictures of the blood vessels in the back of the eye, together with blood test results, to help identify people at high risk for coronary heart disease. If you are already having heart tests, this may provide a non-invasive way to further assess your risk.
Beijing, Beijing MunicipalityAges 18–100 - NCT07559253Recruiting
Heart Care Transition Education Led by Nurses or Doctors
This study tests whether nurse-led or doctor-led education helps young people with congenital heart disease (a heart condition present from birth) transition from pediatric to adult care. The goal is to make this transition smoother and more accessible for all patients, including those with disabilities.
Madison, WisconsinAges 12–26 - NCT07764510Enrolling by invitation
Heart-to-heart support for teens with congenital heart disease
This study tests a support program designed to help teens with congenital heart disease feel better and manage their health. It may improve emotional well-being and heart health.
Columbus, OhioAges 12–18 - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT07375602Recruiting
AI tool to predict complications after VSD closure in children
This study uses artificial intelligence to predict complications in children who have had a specific type of hole in the heart (called a perimembranous ventricular septal defect) repaired with a catheter-based procedure. The goal is to help doctors better identify which children might have problems after the procedure.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07023367Recruiting
Parent navigator program for Latino families of babies with heart disease
This study offers a parent navigator program to help Latino families whose baby had early heart surgery. The program aims to support both the child's recovery and the parents' well-being.
Los Angeles, CaliforniaAges birth+ - NCT02817360RecruitingPhase 4
Preventing heart events in people with type 2 diabetes
This trial tests a heart-focused prevention approach to lower the risk of cardiac (heart) events in adults with type 2 diabetes. It may help by targeting early stress on the heart measured with a specific blood test.
Mödling, Lower AustriaAges 18 years+ - NCT07516145Recruiting
Robotic catheter repair for leaky tricuspid heart valve
This trial tests a new robotic catheter procedure to repair a leaky tricuspid valve (the valve on the right side of your heart). Instead of open-heart surgery, doctors thread a tiny device through a vein in your neck to fix the valve. It may be an option if you have severe leaking and your heart team thinks surgery is too risky for you.
ShatinAges 18–90 - NCT07615790Recruiting
Exercise Program for Postmenopausal Women's Heart Health
This study tests whether a structured exercise program can improve heart rate variability (how your heart adapts to activity) and reduce menopausal symptoms in women after menopause. Researchers want to see if exercise helps your cardiovascular health during this life stage.
Istanbul, AtasehirAges 45–65 - NCT06595147Recruiting
Exercise for heart health in breast cancer survivors
This study tests if a 12-week exercise program improves heart health in women over 60 who have finished treatment for early-stage breast cancer. You will be placed in either an aerobic exercise group or a stretching group to see which helps your heart more.
Edmonton, AlbertaAges 60 years+ - NCT06648733Recruiting
Better medication safety when leaving the hospital for palliative care
This trial studies how to improve medication management when patients with advanced illnesses move from hospital care to home care in Muenster. It aims to make the switch smoother and safer for people who need palliative (comfort-focused) treatment.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06979362RecruitingPhase 2
Study of CDR132L for heart failure with preserved pumping function
This trial tests if CDR132L can improve heart structure and function in people with a type of heart failure where the heart pumps normally but is stiff and thickened. It may help if you have heart failure with preserved ejection fraction and a thickened heart muscle.
Birmingham, AlabamaAges 40–84 - NCT06979375RecruitingPhase 2
Study of CDR132L for heart failure with reduced pumping ability and thickened heart muscle
This trial tests a new medicine called CDR132L to see if it improves heart structure and function in people with heart failure who have a thickened heart muscle and reduced pumping ability. Participants will be randomly assigned to receive either the study drug or a placebo.
Concord, New South WalesAges 40–84 - NCT07482943RecruitingPhase 4
Dapagliflozin for heart function after Fontan procedure
This trial tests whether dapagliflozin, a diabetes drug that also helps the heart, can improve exercise ability and heart function in people who have had the Fontan procedure for a single ventricle heart defect.
Hong KongAges 12 years+ - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT07413198Recruiting
Combined home and clinic exercise coaching for heart failure
This trial tests a program that combines home-based and clinic-based exercise coaching to help people with heart failure get more active. It aims to improve health and quality of life.
Winston-Salem, North CarolinaAges 55 years+ - NCT03895541Recruiting
Test MRI/ultrasound to measure heart stiffness in older heart failure
This study checks whether a noninvasive imaging test can measure how stiff (stiffness) your heart muscle is in older people with certain types of heart failure. It may help doctors better diagnose and sort out the type of heart failure using your scan results.
ParisAges 60–80 - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT07097740Recruiting
Study of a new polymer heart valve for mitral or aortic replacement
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT03821051Recruiting
Registry for heartbeat rhythm problems from structural heart disease
This is a registry that collects information about people with certain dangerous heartbeat rhythm problems caused by structural (anatomical) heart diseases. It may help researchers understand patterns and risks, and improve how these conditions are studied and managed.
Beijing, Beijing MunicipalityAges Any age - NCT06055452RecruitingPhase 4
SGLT2 Inhibitors for Pre-Heart Failure with Hypertension
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for structural heart disease?
- Yes. Clin2 currently lists 77 recruiting structural heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a structural heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a structural heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.