Clinical trials
Thyroid Cancer clinical trials
Below are recruiting thyroid cancer clinical trials, each written for real people, not researchers. We’re tracking 175 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06984991Recruiting
Why some thyroid biopsy samples are hard to evaluate quickly
This trial looks at what makes it harder to quickly tell if a thyroid nodule sample is good enough for diagnosis during your biopsy. It may help doctors improve the procedure for people with suspicious nodules.
Asyut, Asyut GovernorateAges 18 years+ - NCT06959641RecruitingPhase 2
XL092 for advanced thyroid cancer that no longer responds to radioactive iodine
This trial is testing a new oral medication, XL092, for people with advanced thyroid cancer that has stopped responding to radioactive iodine therapy. The goal is to see if XL092 can slow or stop the cancer from growing.
Torrance, CaliforniaAges 18 years+ - NCT05830500RecruitingPhase 4
Anlotinib for advanced medullary thyroid cancer
This trial studies anlotinib in people with advanced or metastatic medullary thyroid cancer that has been getting worse. It aims to see how well the treatment controls the cancer and how safe it is for patients who can’t have curative surgery.
Hefei, AnhuiAges 18–75 - NCT06733740Recruiting
Ultrasound-guided heat treatment for small thyroid cancer
This trial tests a minimally invasive heat treatment (thermal ablation) guided by ultrasound for small papillary thyroid cancers. It may be an option for patients who want to avoid surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05108298Recruiting
Study to improve cancer survey reporting for young adults
This study focuses on collecting better self-reported information (from questionnaires) from young adults with cancer. It may help improve how future cancer trials understand symptoms and quality-of-life needs.
Fairbanks, AlaskaAges 18–39 - NCT06814496RecruitingPhase 1/Phase 2
Radiation and immunotherapy combo for DLL3-positive cancers
This trial combines radiation with an immunotherapy drug called tarlatamab to treat cancers that make a protein called DLL3. The goal is to see if this combination works better than either treatment alone for people with certain types of lung cancer and other tumors that have not responded to prior therapy.
Tucson, ArizonaAges 18–99 - NCT04216732Recruiting
Study of medullary thyroid cancer progression in a registry
This study follows people with medullary thyroid cancer to better understand how the disease changes over time, including in advanced stages. You may help improve future treatment planning and care for people with medullary thyroid cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06849284Recruiting
Predicting thyroid nodule results with a new test
This study tests a new tool (ThyroidPrint) to see if it can accurately predict whether a thyroid nodule with unclear biopsy results is benign or malignant. The goal is to help doctors and patients decide on surgery more confidently.
Truro, CornwallAges 18 years+ - NCT06639191RecruitingEarly Phase 1
Study of a new drug for cancers expressing CD44v6
This trial tests a new radioactive drug called [177Lu]Lu-AKIR001 for patients with certain advanced cancers (like thyroid, head and neck, lung, vulvar, or cervical cancer) that have a specific protein called CD44v6 on their surface. The goal is to see if this treatment can help when standard options have stopped working.
Stockholm, Stockholm CountyAges 18 years+ - NCT03676647Recruiting
Test DNA methylation from thyroid FNA samples to diagnose cancer
This study looks at a molecular test (DNA methylation pattern) using samples taken during fine-needle aspiration (FNA) of thyroid nodules. It aims to help identify which thyroid nodules that looked “unclear” after the first test may be cancer.
Duarte, CaliforniaAges 19 years+ - NCT05766098Recruiting
Genetic testing of papillary thyroid tumor samples
This trial studies the genetic “mutations” in papillary thyroid cancer tumors using tumor tissue. The goal is to better describe tumor genetic patterns, which may help researchers understand the disease.
Milan, MIAges Any age - NCT06286631Recruiting
Predicting lymph node spread in thyroid cancer with a new scale
This trial is testing a new scale to predict if thyroid cancer has spread to nearby lymph nodes. It may help doctors decide on the best treatment for you.
Xi'an, ShaanxiAges 16–80 - NCT03975231RecruitingPhase 1
Targeted drugs and radiation for BRAF-mutated thyroid cancer
This Phase 1 trial studies whether targeted medicines (dabrafenib and trametinib) plus radiation can control an aggressive thyroid cancer with a specific BRAF gene change. It may help by attacking cancer cells that have this mutation and using focused radiation to improve tumor control.
Duarte, CaliforniaAges 18 years+ - NCT07270237Recruiting
New ultrasound imaging for pancreas and thyroid
This study tests new ultrasound methods to better see the pancreas and thyroid. It includes people at high risk for pancreatic cancer, those with pancreatic cancer, those with a thyroid nodule, and healthy volunteers.
Basking Ridge, New JerseyAges 18 years+ - NCT07054229Recruiting
Microwave ablation for low-risk thyroid microcancer
This study looks at whether microwave ablation, a minimally invasive treatment, works as well as surgery for small, low-risk thyroid cancers. It uses special ultrasound and genetic tests to help decide the best treatment.
Guangzhou, GuangdongAges 18–70 - NCT07059507Recruiting
Thyroid cancer in Graves' disease patients having thyroid surgery
This study looks at how often thyroid cancer is found by accident in people with Graves' disease who have their thyroid removed. It helps doctors understand who might be at higher risk so they can plan better care.
Minya, Minya GovernorateAges 18–75 - NCT06468696Recruiting
Scarless thyroid surgery study
This trial is testing a specific type of scarless thyroid surgery (through the chest) and seeing how well it works for people with thyroid tumors that haven't spread. It might be a good fit if you want to avoid a neck scar.
Xi'an, ShaanxiAges 18–75 - NCT06277180Recruiting
PET scan guided surgery for medullary thyroid cancer
This trial uses a special PET scan to help guide surgery for medullary thyroid cancer (MTC). The goal is to see if this scan can make surgery more precise.
BeijingAges 18–75 - NCT06878534Recruiting
Thyroid cancer genetic study for patients with follicular origin
This study looks at the genes and mutations in thyroid cancers that start in follicular cells. It aims to understand how these changes relate to how aggressive the cancer is.
NaplesAges 18 years+ - NCT07410637Recruiting
Thyroid hormones and energy in graves' or thyroid cancer
This trial studies how thyroid hormone levels affect your body's use of sugar and energy. It may help people newly diagnosed with Graves' disease or thyroid cancer understand their metabolism better.
Ulm, Baden-WurttembergAges Any age - NCT04589624RecruitingPhase 1
MRI scan to monitor response in head and neck cancers
This Phase 1 study tests an investigational MRI scan (hpMRI) to help doctors see how thyroid cancer and other head-and-neck cancers respond to treatment like radiation or other medicines. If you’re eligible, the scan may help track treatment effects more closely, though it’s still being studied for this purpose.
Houston, TexasAges 18 years+ - NCT04290663RecruitingPhase 3
Radioiodine decision after thyroid surgery for intermediate-risk cancer
This study compares two approaches after thyroid surgery: giving radioactive iodine right away versus deciding based on follow-up test results. It aims to see which approach better helps people with intermediate-risk differentiated thyroid cancer.
Pointe à Pitre, GuadeloupeAges 18 years+ - NCT05599139Recruiting
Testing iodine uptake after a low-iodine diet
This study looks at how much iodine your body absorbs after you follow a low-iodine diet before radioactive iodine treatment (131I) for thyroid cancer. It may help improve how safely and effectively this treatment is planned.
Groningen, Provincie GroningenAges 18–75 - NCT06133374Recruiting
Genetic testing accuracy: needle biopsy vs. surgery
This study compares genetic testing results from a small needle biopsy to those from the surgically removed thyroid tissue. It aims to see if the biopsy alone can accurately predict the cancer's genetics, which could help guide treatment decisions.
Calgary, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for thyroid cancer?
- Yes. Clin2 currently lists 175 recruiting thyroid cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thyroid cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thyroid cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.