Clinical trials
Thyroid Cancer clinical trials
Below are recruiting thyroid cancer clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05830500RecruitingPhase 4
Anlotinib for advanced medullary thyroid cancer
This trial studies anlotinib in people with advanced or metastatic medullary thyroid cancer that has been getting worse. It aims to see how well the treatment controls the cancer and how safe it is for patients who can’t have curative surgery.
Hefei, AnhuiAges 18–75 - NCT06814496RecruitingPhase 1/Phase 2
Radiation and immunotherapy combo for DLL3-positive cancers
This trial combines radiation with an immunotherapy drug called tarlatamab to treat cancers that make a protein called DLL3. The goal is to see if this combination works better than either treatment alone for people with certain types of lung cancer and other tumors that have not responded to prior therapy.
Gilbert, ArizonaAges 18–99 - NCT04216732Recruiting
Study of medullary thyroid cancer progression in a registry
This study follows people with medullary thyroid cancer to better understand how the disease changes over time, including in advanced stages. You may help improve future treatment planning and care for people with medullary thyroid cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06849284Recruiting
Predicting thyroid nodule results with a new test
This study tests a new tool (ThyroidPrint) to see if it can accurately predict whether a thyroid nodule with unclear biopsy results is benign or malignant. The goal is to help doctors and patients decide on surgery more confidently.
Truro, CornwallAges 18 years+ - NCT06639191RecruitingEarly Phase 1
Study of a new drug for cancers expressing CD44v6
This trial tests a new radioactive drug called [177Lu]Lu-AKIR001 for patients with certain advanced cancers (like thyroid, head and neck, lung, vulvar, or cervical cancer) that have a specific protein called CD44v6 on their surface. The goal is to see if this treatment can help when standard options have stopped working.
Stockholm, Stockholm CountyAges 18 years+ - NCT03676647Recruiting
Test DNA methylation from thyroid FNA samples to diagnose cancer
This study looks at a molecular test (DNA methylation pattern) using samples taken during fine-needle aspiration (FNA) of thyroid nodules. It aims to help identify which thyroid nodules that looked “unclear” after the first test may be cancer.
Duarte, CaliforniaAges 19 years+ - NCT06286631Recruiting
Predicting lymph node spread in thyroid cancer with a new scale
This trial is testing a new scale to predict if thyroid cancer has spread to nearby lymph nodes. It may help doctors decide on the best treatment for you.
Xi'an, ShaanxiAges 16–80 - NCT05766098Recruiting
Genetic testing of papillary thyroid tumor samples
This trial studies the genetic “mutations” in papillary thyroid cancer tumors using tumor tissue. The goal is to better describe tumor genetic patterns, which may help researchers understand the disease.
Milan, MIAges Any age - NCT03975231RecruitingPhase 1
Targeted drugs and radiation for BRAF-mutated thyroid cancer
This Phase 1 trial studies whether targeted medicines (dabrafenib and trametinib) plus radiation can control an aggressive thyroid cancer with a specific BRAF gene change. It may help by attacking cancer cells that have this mutation and using focused radiation to improve tumor control.
Duarte, CaliforniaAges 18 years+ - NCT07270237Recruiting
New ultrasound imaging for pancreas and thyroid
This study tests new ultrasound methods to better see the pancreas and thyroid. It includes people at high risk for pancreatic cancer, those with pancreatic cancer, those with a thyroid nodule, and healthy volunteers.
Basking Ridge, New JerseyAges 18 years+ - NCT07054229Recruiting
Microwave ablation for low-risk thyroid microcancer
This study looks at whether microwave ablation, a minimally invasive treatment, works as well as surgery for small, low-risk thyroid cancers. It uses special ultrasound and genetic tests to help decide the best treatment.
Guangzhou, GuangdongAges 18–70 - NCT07059507Recruiting
Thyroid cancer in Graves' disease patients having thyroid surgery
This study looks at how often thyroid cancer is found by accident in people with Graves' disease who have their thyroid removed. It helps doctors understand who might be at higher risk so they can plan better care.
Minya, Minya GovernorateAges 18–75 - NCT07620574Enrolling by invitationPhase 3
Long-Term Study Continuing Cancer Treatment from Previous Trial
This study lets people who were in an earlier Exelixis cancer treatment trial continue receiving the same treatment if it's still helping them. It's designed to see how safe and effective the treatment is over a longer period.
Bay Shore, New YorkAges Any age - NCT07410637Recruiting
Thyroid hormones and energy in graves' or thyroid cancer
This trial studies how thyroid hormone levels affect your body's use of sugar and energy. It may help people newly diagnosed with Graves' disease or thyroid cancer understand their metabolism better.
Ulm, Baden-WurttembergAges Any age - NCT06878534Recruiting
Thyroid cancer genetic study for patients with follicular origin
This study looks at the genes and mutations in thyroid cancers that start in follicular cells. It aims to understand how these changes relate to how aggressive the cancer is.
NaplesAges 18 years+ - NCT06277180Recruiting
PET scan guided surgery for medullary thyroid cancer
This trial uses a special PET scan to help guide surgery for medullary thyroid cancer (MTC). The goal is to see if this scan can make surgery more precise.
BeijingAges 18–75 - NCT04589624RecruitingPhase 1
MRI scan to monitor response in head and neck cancers
This Phase 1 study tests an investigational MRI scan (hpMRI) to help doctors see how thyroid cancer and other head-and-neck cancers respond to treatment like radiation or other medicines. If you’re eligible, the scan may help track treatment effects more closely, though it’s still being studied for this purpose.
Houston, TexasAges 18 years+ - NCT06158360Recruiting
Post-surgery symptoms after thyroid cancer surgery
This study looks at how you feel after thyroid surgery for cancer. It tests whether adding Chinese medicine treatments can help with symptoms like pain or fatigue during recovery.
Gyeonggi-doAges 19 years+ - NCT06141369Recruiting
Personalized mRNA vaccine for advanced endocrine tumors
This trial tests a personalized mRNA vaccine made from your tumor's genetic information. It is for people with advanced endocrine tumors who have no standard treatment options left, and aims to help the immune system fight the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07235566RecruitingPhase 2
MRG003 plus pucotenlimab for advanced thyroid cancer (ATC/PDTC)
This trial tests two drugs together: MRG003 (a targeted therapy that delivers chemo directly to EGFR-positive cancer cells) and pucotenlimab (an immunotherapy that helps your immune system attack the cancer). It is for people with a rare and aggressive thyroid cancer (ATC or PDTC) whose tumors have the EGFR protein and have grown despite previous treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06671184Recruiting
Predicting difficult thyroid surgery for less scarring
This trial looks at a tool doctors can use to predict if a certain type of thyroid surgery (through the mouth or under the chin) will be challenging. It helps people who want less visible scarring after their thyroid cancer surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT06855680Recruiting
EMIRATES: Observing low-risk thyroid cancer without completion surgery
This study tests whether it is safe to monitor small, low-risk thyroid cancers (1–4 cm) instead of removing the remaining thyroid tissue after initial surgery. It may help you avoid a second operation and lifelong medication if your cancer is truly low-risk.
WiganAges 18 years+ - NCT06840106Recruiting
Steam therapy for breathing issues after thyroid removal
This study tests whether breathing in steam can help with sore throat, cough, or other breathing problems that sometimes happen after a thyroid surgery. If you had a thyroid tumor removed and are having these symptoms, this treatment might help you feel better.
Goyang-si, Gyeonggi-doAges 19–69 - NCT06725576Recruiting
Comparing microwave ablation vs. surgery for low-risk thyroid cancer
This study compares a less invasive procedure (microwave ablation) with traditional surgery for treating a small, low-risk papillary thyroid cancer. If you have a single, small tumor with certain low-risk gene changes, you might be able to avoid surgery and have a quicker recovery.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for thyroid cancer?
- Yes. Clin2 currently lists 172 recruiting thyroid cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thyroid cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thyroid cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.