Clinical trials
Thyroid clinical trials
Below are recruiting thyroid clinical trials, each written for real people, not researchers. We’re tracking 337 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05189808Recruiting
Radiofrequency treatment for certain thyroid nodules
This trial studies radiofrequency ablation, a procedure that shrinks a thyroid nodule, for thyroid nodules that are unclear on biopsy but have a reassuring “molecular” test. If you have a Bethesda III nodule that tests benign on specific genetic tests, you may be a good candidate to see if this approach helps safely.
New York, New YorkAges 18 years+ - NCT05189821Recruiting
Study treatment for tiny thyroid cancer without surgery
This trial studies a treatment option for papillary thyroid microcarcinoma in adults who either do not want surgery or cannot safely have surgery. It may help people find a non-surgical approach for a very small thyroid cancer.
New York, New YorkAges 18 years+ - NCT01109420Recruiting
Family study of non-medullary thyroid cancer and genetics
This study looks at families affected by non-medullary thyroid cancer to understand patterns and possible genetic risk. You may be able to join even if you personally do not have the cancer, as long as you have the right family history and can complete a questionnaire.
Bethesda, MarylandAges 7–90 - NCT06482086RecruitingPhase 2
Using tumor models to guide drug choice for advanced thyroid cancer
This trial tests whether growing your tumor cells in a lab (as organoids) can help doctors pick the best drugs for advanced thyroid cancer that is hard to remove surgically. It's for people with different thyroid cancer types who have tumors growing outside the thyroid or into nearby areas.
Chengdu, SichuanAges 18 years+ - NCT05852223RecruitingPhase 2
Pembrolizumab for high-risk thyroid cancer that cannot be fully removed
This study tests pembrolizumab (an immune therapy) in people with high-risk thyroid cancer that is hard to treat with surgery alone. It looks at whether this drug can reduce persistent or recurrent cancer after your planned treatment.
Pavia, LombardyAges 18 years+ - NCT06359847RecruitingPhase 2
ST-1898 for advanced thyroid cancer that no longer responds to iodine therapy
This trial tests an experimental drug called ST-1898 for people with advanced thyroid cancer that has stopped responding to radioactive iodine treatment and has progressed after at least one targeted therapy. It aims to see if ST-1898 can shrink tumors or slow the disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07552103Enrolling by invitation
How Thyroid Problems Affect Women's Health
This study explores how thyroid dysfunction (when the thyroid gland doesn't work properly) affects women's bodies and wellbeing. Researchers want to understand these effects better to help improve care for women with thyroid issues.
UşakAges 18–55 - NCT06739330Recruiting
Thyroid function and fatty liver disease study
This study looks at how your thyroid might be linked to fatty liver disease (MAFLD). It aims to help researchers understand if thyroid problems play a role in this condition, which could lead to better treatments.
Tanta, El-GharbiaAges 18 years+ - NCT05989425RecruitingPhase 2
Surufatinib before surgery for advanced thyroid cancer
This trial tests whether the drug Surufatinib, given before surgery, can shrink locally advanced or metastatic thyroid cancer. It's a targeted therapy that blocks blood vessels that feed tumors, and is given as a pill to see if it makes the cancer easier to remove.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06483893Recruiting
Numbing blocks for awake breathing tube placement in neck surgery
This trial compares two numbing techniques for placing a breathing tube while you're awake. It aims to find which method works better for people with limited neck movement who need neck surgery.
Banī Suwayf, Beni Suweif GovernorateAges 18–65 - NCT05789667Recruiting
Study lenvatinib effects by patient gender in thyroid cancer
This study looks at whether safety and treatment results with lenvatinib differ between genders for people with iodine-refractory differentiated thyroid cancer. If you have already been treated with lenvatinib and meet the basic requirements, you may be asked to join after consenting.
RomeAges 18 years+ - NCT07022236Recruiting
Thyroid Function in Hemodialysis Patients
This study checks thyroid function in people who are on long-term hemodialysis for kidney failure. It aims to see how common thyroid issues are in this group, which could help improve care.
SohagAges 13–80 - NCT07397234Recruiting
Awake breathing tube placement study
This study tests two ways to numb the neck for placing a breathing tube while you're awake. It might help if you have a difficult airway that makes regular intubation harder.
Nanjing, JiangsuAges 18–85 - NCT07237373Recruiting
Heat ablation for benign thyroid nodules
This trial tests a minimally invasive procedure called thermal ablation (using heat) to shrink benign thyroid nodules that cause symptoms like pressure or cosmetic issues, or overactive (hot) nodules. It offers an alternative to surgery or radioactive iodine.
BrugesAges 18 years+ - NCT07287748RecruitingPhase 1
Studying AF-001 for advanced thyroid cancer
This trial tests a new drug called AF-001 for people with thyroid cancer that has spread and can't be removed with surgery. It's for those who didn't benefit from or can't take standard treatments, or who haven't had radioactive iodine therapy yet.
KashiwaAges 18 years+ - NCT06333587Recruiting
Minimally invasive thyroid treatments for small thyroid cancer
This trial is testing less invasive treatments for a very small, slow-growing type of thyroid cancer (papillary thyroid microcarcinoma). If you have this specific cancer and are a candidate for a non-surgical procedure, the study will check how well these treatments work.
MilanAges 18 years+ - NCT07589660Recruiting
Online follow-up program after thyroid surgery
This study tests whether a structured online follow-up program helps patients recover better after thyroid surgery. You'll use your smartphone to check in with your care team instead of always coming to the hospital.
Chengdu, SichuanAges 18–75 - NCT07516990Recruiting
Parathyroid Tissue Injection During Thyroid Surgery
This study tests whether injecting parathyroid tissue into the forearm during thyroid surgery helps prevent low calcium levels after surgery. Parathyroid glands control calcium in your body, and they can be damaged during thyroid surgery.
Vienna, State of ViennaAges 18 years+ - NCT07747103RecruitingPhase 3
Porcine thyroid extract for hypothyroidism
This trial tests a new porcine (pig) thyroid hormone replacement tablet for people with primary hypothyroidism (underactive thyroid). It aims to see if this treatment is safe and effective compared to current levothyroxine therapy.
Modesto, CaliforniaAges 18–75 - NCT07173621Enrolling by invitation
Comparing a wound-healing gel to standard care after thyroid or parathyroid surgery
This study compares a special wound-healing gel (called AMNIOEFFECT) with standard care after thyroid or parathyroid surgery. The goal is to see if the gel helps your incision heal better.
Sarasota, FloridaAges 18 years+ - NCT06959511RecruitingPhase 2
Zanzalintinib for advanced thyroid cancer before surgery
This trial tests a drug called zanzalintinib for people with advanced thyroid cancer that has spread nearby. The goal is to see if taking this pill before surgery can shrink the tumor and make it easier to remove.
Ann Arbor, MichiganAges 18 years+ - NCT07328243Recruiting
New treatment for thyroid cancer that spread to neck lymph nodes
This study tests a minimally invasive treatment called irreversible electroporation for thyroid cancer that has come back or spread to lymph nodes in the neck. It may be an option for people who can't have another surgery or for whom radioactive iodine therapy hasn't worked.
Guangzhou, GuangdongAges 18 years+ - NCT07438405RecruitingPhase 2
Long-term safety study of AMG 732 for thyroid eye disease
This trial tests the long-term safety and effectiveness of AMG 732 for people with moderate-to-severe thyroid eye disease who have already completed an Amgen study of this drug. It allows continued treatment without needing immediate eye surgery.
Little Rock, ArkansasAges 18–99 - NCT07716397Recruiting
MRI study for thyroid eye disease diagnosis and care
This study uses MRI scans of the eye area to better understand and classify thyroid eye disease (TED). It aims to help doctors predict outcomes and personalize treatment. You may be eligible if you have stable TED or are a healthy volunteer.
Shanghai, Huangpu DistrictAges 18–75
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Common questions
- Are there clinical trials for thyroid?
- Yes. Clin2 currently lists 337 recruiting thyroid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thyroid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thyroid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.