Clinical trials
Transplant; Failure, Heart clinical trials
Below are recruiting transplant; failure, heart clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05450328RecruitingPhase 2
Breathing medicine to help heart-lung machine separation after surgery
This Phase 2 trial tests whether inhaled medicines (milrinone and epoprostenol) can make it easier to separate from the heart-lung machine during cardiac surgery. It may help reduce the risk of a difficult transition off the machine for the right patients.
Montreal, QuebecAges 18 years+ - NCT04844944Recruiting
Heart registry for adults with heart failure, CAD, or atrial fibrillation
This is a hospital-based study that collects standardized information about adults with specific heart conditions—heart failure, coronary artery disease, or atrial fibrillation. It may help doctors and researchers better understand these diseases and improve future care.
BerlinAges 18 years+ - NCT04666454RecruitingPhase 4
Medication trial for broken heart (Takotsubo) syndrome
This trial tests an optimized medication approach for people diagnosed with Takotsubo (“broken heart”) syndrome. It may help clinicians find a safer and more effective treatment plan after this heart condition.
AarhusAges 18 years+ - NCT07835828Recruiting
Optimised heart and kidney protection for chronic kidney disease and heart disease
This study tests a new approach to protect the heart and kidneys in people with both chronic kidney disease and heart or blood vessel problems. By optimising treatment, researchers hope to reduce the risk of further kidney or heart damage.
SvendborgAges 18 years+ - NCT03398369Recruiting
Imaging study to guide heart failure device treatment
This study uses advanced heart imaging to better understand heart function in people who may benefit from a cardiac resynchronization therapy (CRT) device. It aims to find ways to improve how doctors choose treatment and tailor care.
Charlottesville, VirginiaAges 20–90 - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT07858799Recruiting
Study of a new device for heart failure with reduced pumping ability
This trial tests a new device that creates a small shunt (passage) in the heart to help relieve pressure and improve symptoms in people with heart failure and a weak heart pump. The goal is to see if the device is safe and helpful for patients like you.
Cologne, GermanyAges 18 years+ - NCT03523416Recruiting
Shunt device for heart failure with reduced pumping function
This trial studies a small device placed in the heart to create a passage that may help relieve pressure and improve symptoms in people with heart failure and a weak pumping function. It aims to see if the device is safe and helpful for daily life.
La Jolla, CaliforniaAges 18 years+ - NCT06055504Recruiting
Personalized defibrillator plan for non-ischemic heart failure (SPANISH-1)
This trial is testing a personalized approach to deciding who gets an implantable defibrillator (ICD) for people with heart failure due to dilated cardiomyopathy (not from blocked arteries). It aims to see if MRI scans and other factors can better match the device to those who need it most.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06208007Recruiting
Predicting heart failure with stiff arteries
This study looks at whether stiffer arteries can help predict a type of heart failure where the heart doesn't relax properly (HFpEF). It's for people who have risk factors like high blood pressure, diabetes, or being older, and who may have early signs of heart trouble.
Göttingen, Lower SaxonyAges 18 years+ - NCT05327062Recruiting
Noninvasive mapping to guide a heart resynchronization device
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
Chicago, IllinoisAges 18 years+ - NCT07666698RecruitingPhase 1/Phase 2
Metformin to improve heart function after LVAD implant
This trial tests if metformin, a medicine commonly used for diabetes, can help improve heart function in people who have a mechanical heart pump (LVAD). You may be able to join if you are between 18 and 75, have a continuous-flow LVAD, and have a condition called insulin resistance (where your body doesn't use insulin well) but your blood sugar levels are well-controlled.
Nanjing, JiangsuAges 18–75 - NCT07632586Recruiting
First-in-Human Heart Pump Implant Study
This trial tests a new tiny heart pump called the Icoms Flowmaker for patients with severe heart failure who cannot have a standard heart pump. The device may help your heart pump blood better and improve your ability to do daily activities.
PragueAges 18–80 - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT07489105Recruiting
Yoga for better thinking with heart failure
This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.
Auburn, AlabamaAges 55 years+ - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT07413198Recruiting
Combined home and clinic exercise coaching for heart failure
This trial tests a program that combines home-based and clinic-based exercise coaching to help people with heart failure get more active. It aims to improve health and quality of life.
Winston-Salem, North CarolinaAges 55 years+ - NCT07400042Recruiting
Peripheral vein pressure test for heart failure patients
This study tests if measuring pressure from a vein in the arm can help guide treatment for people hospitalized with worsening heart failure. It aims to understand if this simple procedure could replace or reduce the need for more invasive monitoring.
Milwaukee, WisconsinAges 18 years+ - NCT07393009Recruiting
Study of a new left bundle branch area pacing system
This study tests a new type of pacemaker system that delivers pacing to the left side of the heart through a lead placed deep in the wall between the lower chambers. The goal is to see if this approach works well for people who need a pacemaker or CRT.
AdelaideAges 18 years+ - NCT07372196Recruiting
Left bundle branch pacing after myectomy for hypertrophic cardiomyopathy
This trial is testing a new way to pace the heart (left bundle branch pacing) for people with hypertrophic cardiomyopathy who still have a dangerous heart rhythm problem after myectomy surgery. It aims to see if this pacing can reduce the risk of sudden cardiac death.
Novosibirsk, Novosibirsk OblastAges 18–75 - NCT05828719Recruiting
Compare heart stent treatment vs medicines for weak heart function
This study looks at whether opening blocked heart arteries with a stent (a PCI procedure) works better than staying on heart medicines for people with weakened pumping function and certain types of heart failure. It may help patients by testing which approach best improves outcomes over time.
SeoulAges 19 years+ - NCT07273838RecruitingPhase 2
SGLT2 inhibitor for acute heart and kidney failure
This study tests whether a medicine called an SGLT2 inhibitor (which lowers blood sugar and helps the kidneys) can improve outcomes for people with acute heart failure and kidney problems. Participation involves taking the study drug or a placebo for a short time.
New Haven, ConnecticutAges 18–85 - NCT06378632Recruiting
Heart failure monitoring app study
This study tests a smartphone app that listens to your voice to detect early signs of heart failure worsening. It aims to help you avoid hospital stays by catching problems sooner.
Fairhope, AlabamaAges 22 years+
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Common questions
- Are there clinical trials for transplant; failure, heart?
- Yes. Clin2 currently lists 266 recruiting transplant; failure, heart studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a transplant; failure, heart trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a transplant; failure, heart trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.