Clinical trials
Valvular Heart Disease Patients clinical trials
Below are recruiting valvular heart disease patients clinical trials, each written for real people, not researchers. We’re tracking 196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT07748858Recruiting
Heart care support for older African American patients
This study aims to improve care for older African American patients with heart conditions and other health problems. It tests ways to provide more patient-centered support.
Birmingham, AlabamaAges 50–99 - NCT07560436RecruitingPhase 2
Stents for Heart Failure With Normal Pumping
This trial tests whether placing stents in coronary arteries helps patients with heart failure who still have a strong-pumping heart. The study aims to see if improving blood flow to the heart reduces symptoms and improves quality of life.
LondonAges 18 years+ - NCT06938412Recruiting
Exercise and Fitbit for Afib patients
This study tests whether using a Fitbit activity tracker and a supportive exercise program helps people with AFib become more active. It may help you feel better and manage your heart rhythm.
New York, New YorkAges 18 years+ - NCT06845410Recruiting
INR-CAD: inflammation-related coronary artery disease study
This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT06252870RecruitingPhase 2
Comparing two conditioning regimens for stem cell transplant
This trial tests two different chemotherapy and radiation plans (conditioning regimens) given before a stem cell transplant from a matched donor. Both are followed by the same drugs to prevent graft-versus-host disease. The goal is to find which regimen works better for people with blood cancers.
AngersAges 18–70 - NCT06506448Recruiting
Studying non-blocked arteries after a heart attack
This study looks at arteries in the heart that aren't the one that caused the heart attack. It uses a special CT scan to understand these arteries better in people who have already had a procedure to open the blocked artery.
Bournemouth, DorsetAges 18–85 - NCT01696734RecruitingPhase 3
Domperidone for difficult stomach and reflux problems
This trial studies whether domperidone can help people whose stomach or reflux symptoms did not improve with usual treatments. It focuses on symptoms like slow stomach emptying, hard-to-control acid reflux, or severe indigestion.
Houston, TexasAges 16 years+ - NCT02772367Recruiting
Make heart muscle cells from blood or skin in breast cancer
This study grows heart muscle cells from your blood or skin to better understand why some people develop heart problems from HER2 cancer treatments. You may be helping researchers learn how to predict and prevent treatment-related heart damage.
New York, New YorkAges 18 years+ - NCT07552142Recruiting
Heart Failure Check-In: Using Questionnaires to Spot Early Warning Signs
This study asks heart failure patients who recently were hospitalized to answer regular questionnaires about how they're feeling. Researchers want to see if these questions can detect when heart failure is getting worse before a patient needs emergency care.
Moscow, Non-US/Non-CanadianAges 18 years+ - NCT06055452RecruitingPhase 4
SGLT2 Inhibitors for Pre-Heart Failure with Hypertension
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07053254Recruiting
Studying vein grafts in older heart bypass patients
This trial looks at how vein grafts work in older adults who need coronary artery bypass surgery. It aims to understand why grafts sometimes fail, so doctors can improve treatment.
SeoulAges 19–100 - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT05628779Enrolling by invitation
Clip procedure to repair a leaking tricuspid valve
This trial studies a minimally invasive “edge-to-edge” clip procedure to reduce severe leakage of the tricuspid valve. It’s for people who still feel unwell despite standard treatments and may be too high-risk for open-heart surgery.
AmsterdamAges 18 years+ - NCT05860400Recruiting
Testing add-on treatment to calm artery inflammation after heart procedures
This study looks at whether a comprehensive add-on treatment—starting with immune medicine and then a heart procedure when needed—can improve outcomes for people whose coronary artery disease is getting worse quickly. It focuses on cases where inflammation is likely driving new artery blockages or worsening chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Phoenix, ArizonaAges 18–80 - NCT07462624Recruiting
Comparing treatments for a failing surgical aortic valve
This trial compares two ways to treat a failing aortic valve that was replaced with a tissue valve during surgery: another surgical replacement or a less invasive catheter-based valve-in-valve procedure. It is for people with low to intermediate surgical risk who are between 18 and 75 years old.
Leipzig, SaxonyAges 18–75 - NCT04416581RecruitingPhase 4
Compare two stomach-protecting medicines to prevent bleeding
This trial compares a potassium-competitive acid blocker to a proton pump inhibitor to help prevent stomach or intestinal bleeding in people at high risk who take blood-thinning medicines. It may help reduce dangerous GI bleeding while you stay on heart/stroke medicines.
AnyangAges 19 years+ - NCT06653387Recruiting
Testing a new carotid stent with blood-flow reversal for high-risk patients
This trial tests a new carotid stent system used with a special blood-flow reversal device to treat blocked carotid arteries. It is for people with high-risk conditions who might not be good candidates for traditional open surgery, and aims to see if the stent is safe and effective in preventing strokes.
Sacramento, CaliforniaAges 18–79 - NCT05672836RecruitingPhase 4
Enavogliflozin after TAVR for heart narrowing with mild heart weakness
This trial tests enavogliflozin (a diabetes medication that may help the heart) in people who have had a TAVR procedure for severe aortic stenosis. It looks at whether the medicine can improve outcomes for people with symptoms and mildly reduced or preserved pumping function.
Bucheon-siAges 19 years+ - NCT06219239Recruiting
Gene therapy for transfusion-dependent beta-thalassemia
This trial tests a new gene therapy for people with beta-thalassemia who need regular blood transfusions. It uses a virus to deliver a working gene into your own stem cells, then those cells are put back into your body to help your body make healthy red blood cells.
Tianjin, Tianjin MunicipalityAges 3–35 - NCT07072858Recruiting
Heart MRI to Predict Recovery After Heart Attack
This study is testing if a special heart MRI taken within a week of a STEMI heart attack can help doctors predict your recovery and future risks. It may help tailor your follow-up care.
BeijingAges 18–80 - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+
Hear when a new Valvular Heart Disease Patients trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for valvular heart disease patients?
- Yes. Clin2 currently lists 196 recruiting valvular heart disease patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valvular heart disease patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valvular heart disease patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.