Clinical trials
Valvular Heart Disease Patients clinical trials
Below are recruiting valvular heart disease patients clinical trials, each written for real people, not researchers. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT05329285Recruiting
Compare bypass or stent for heart weakness from blocked arteries
This study compares two ways to improve blood flow in people with weakened heart pumping (ischemic cardiomyopathy): bypass surgery (CABG) versus stent treatment (PCI). It aims to see which approach works better when the heart still has enough at-risk muscle and when best medical therapy is already started.
GothenburgAges 18 years+ - NCT04695106RecruitingPhase 4
Blood Thinner and Heart Attack Prevention Study
This study tests whether taking dabigatran (a blood thinner) combined with ticagrelor (a blood clot preventer) is safe and effective for patients with irregular heart rhythm (atrial fibrillation) who recently had a heart attack and received a stent. The goal is to prevent future blood clots while minimizing bleeding risks.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT07483372RecruitingPhase 1
SC101 injection for resistant hypertension with kidney disease
This early-phase trial tests an injection called SC101 into the fat around your kidney. It aims to help lower blood pressure in people whose hypertension is poorly controlled despite multiple medications and who have moderate to severe chronic kidney disease.
Suzhou, JiangsuAges 18–65 - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07010029Recruiting
Heart vein device for angina with no blocked arteries
This trial tests a special device placed in a vein of the heart to help patients who have chest pain (angina) but no major blockages in their heart arteries. It is designed for people who have tried maximum medications but still have symptoms.
WarsawAges 18 years+ - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT07486791Recruiting
Baduanjin exercise for heart health after heart attack
This study tests whether a gentle exercise called 'Lying-Sitting-Standing' Baduanjin can improve heart and lung function and quality of life in people who have had a heart attack and also have heart failure.
Taiyuan, ShanxiAges Up to 85 years - NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT07122544Recruiting
Salt chamber pulmonary rehab for COPD
This study tests whether doing pulmonary rehab (breathing and exercise training) in a salt chamber can help people with COPD breathe and feel better. It is for people whose COPD is stable and who can move independently.
Krakow, MałopolskaAges 18 years+ - NCT06875128RecruitingPhase 2
Liver-directed chemo with standard chemo for breast cancer
This trial tests if giving a high dose of chemotherapy directly into the liver, followed by standard chemotherapy, is safe and works better than standard chemo alone for people with breast cancer that has spread mostly to the liver.
Tampa, FloridaAges 18 years+ - NCT06607458RecruitingPhase 2
Liver-focused chemo for metastatic colorectal cancer
This trial tests giving high-dose melphalan directly into the liver's blood supply, followed by standard cancer therapy, for people whose colorectal cancer has spread mainly to the liver. The goal is to see if this approach is safer and works better than standard treatment alone.
Duarte, CaliforniaAges 18 years+ - NCT05152888RecruitingPhase 4
Testing a cholesterol drug to improve heart blood flow on scans
This trial studies whether lowering LDL (“bad cholesterol”) with a PCSK-9 inhibitor (evolocumab) improves blood flow to the heart, measured by special PET scans. It’s for people over a certain age who have stable coronary artery disease and a higher risk of heart problems.
Boston, MassachusettsAges 50–90 - NCT05793996RecruitingPhase 4
Testing an iron infusion for iron deficiency in HFpEF
This study checks how common iron deficiency is in people with HFpEF (heart failure with preserved pumping strength) and tests whether an iron infusion (Ferinject®) improves health. It targets people with stable heart symptoms and lab results showing low iron stores or related iron deficiency.
TomskAges 18 years+ - NCT06518681Enrolling by invitation
Testing a new polymer heart valve for aortic disease
This trial tests a new type of artificial heart valve made of polymer (a special plastic-like material) for people with severe aortic valve disease. It aims to see if the valve is safe and works well, giving you an option for a replacement valve that might last longer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07262983RecruitingPhase 1
Baricitinib for Job syndrome with lupus or eczema
This study tests if baricitinib, a pill that changes how your immune system works, is safe and tolerable for people with Job syndrome who also have lupus-like disease or severe eczema. It might offer a new treatment option for these skin and immune problems.
Bethesda, MarylandAges 12–120 - NCT06304857RecruitingPhase 3
Protecting the heart with dapagliflozin during breast cancer treatment
This trial tests if the diabetes drug dapagliflozin can protect the heart in people with breast cancer receiving a type of chemotherapy called anthracyclines. You may be able to join if you are between 18 and 80, have stage I-III breast cancer, and are about to start anthracycline treatment within the next 60 days.
Wroclaw, Lower Silesian VoivodeshipAges 18–80 - NCT05834803Recruiting
Stenting narrowed kidney artery to help high-risk patients
This trial studies whether placing a small stent in a severely narrowed kidney artery can improve outcomes for people with high-risk, artery-hardening kidney blood-flow problems. It focuses on people whose high blood pressure or kidney function has been getting worse despite multiple medications.
Aarhus NAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT07748858Recruiting
Heart care support for older African American patients
This study aims to improve care for older African American patients with heart conditions and other health problems. It tests ways to provide more patient-centered support.
Birmingham, AlabamaAges 50–99 - NCT07560436RecruitingPhase 2
Stents for Heart Failure With Normal Pumping
This trial tests whether placing stents in coronary arteries helps patients with heart failure who still have a strong-pumping heart. The study aims to see if improving blood flow to the heart reduces symptoms and improves quality of life.
LondonAges 18 years+ - NCT06938412Recruiting
Exercise and Fitbit for Afib patients
This study tests whether using a Fitbit activity tracker and a supportive exercise program helps people with AFib become more active. It may help you feel better and manage your heart rhythm.
New York, New YorkAges 18 years+ - NCT06845410Recruiting
INR-CAD: inflammation-related coronary artery disease study
This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for valvular heart disease patients?
- Yes. Clin2 currently lists 191 recruiting valvular heart disease patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a valvular heart disease patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a valvular heart disease patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.