Clinical trials
Vascular Dysfunction clinical trials
Below are recruiting vascular dysfunction clinical trials, each written for real people, not researchers. We’re tracking 38 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05215171Recruiting
Study breathing and blood changes after 9/11 exposure
This study looks at how breathing problems and blood vessel/heart issues may happen after World Trade Center (WTC) dust exposure. It uses blood samples and breathing tests to understand who may be affected and to compare people with and without WTC-related airway reactivity.
New York, New YorkAges 21–90 - NCT05388032Recruiting
Test whether lowering salt improves blood vessel health
This trial studies whether a lower-salt plan can improve how your blood vessels work. It’s meant for adults with higher blood pressure who may be at risk for heart and blood vessel problems.
New Orleans, LouisianaAges 40 years+ - NCT05659589Recruiting
Using a kidney toxin level to predict heart effects in AKI
This study looks at whether measuring indoxyl sulfate, a substance that can build up when kidneys are injured, can help predict how blood vessels and the heart are affected during acute kidney injury (AKI). It may help doctors understand who is at higher risk of heart-related problems while AKI is happening.
AmiensAges 18 years+ - NCT03527420Recruiting
Study of body fat, blood vessels, and DNA changes
This study looks at how having a high body mass index affects blood vessel function and changes in DNA. It may help researchers understand why weight-related health risks happen and how bariatric surgery could help.
Chicago, IllinoisAges 18–50 - NCT06419959Recruiting
NightWare watch for better sleep and heart health in veterans with PTSD
This study tests if a special watch (NightWare) can help veterans with PTSD who have nightmares sleep better and improve heart health. The watch vibrates gently during nightmares to reduce them without waking you up.
Aurora, ColoradoAges 22–88 - NCT03538639Recruiting
Study blood and tissue samples for vascular disease discovery
This study collects blood (and sometimes tissue samples) from people who may have vascular (blood vessel) problems and from certain pregnant participants. Researchers use the samples to better understand vascular disease and to help guide future research.
Bethesda, MarylandAges 2–100 - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT07311512Recruiting
Gum treatment and mouthwash study for gum disease
This trial tests if a professional gum cleaning combined with a special mouthwash can improve gum health and blood vessel function. It may help people with early gum disease who haven't had recent gum treatment.
Portsmouth, HampshireAges 30–75 - NCT04769206RecruitingPhase 1/Phase 2
Boost nerve signaling to improve blood vessel function
This study tests a treatment aimed at increasing “rest-and-digest” nerve activity to improve how blood vessels work, especially in people with vascular oxidative stress. It is designed for African American adults and looks at whether the intervention can improve blood vessel-related health markers.
Nashville, TennesseeAges 18–60 - NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+ - NCT04916340Recruiting
Exercise program study for heart blood vessel function and anxiety
This study tests whether an exercise training program can improve how well blood vessels work in people with PTSD or generalized anxiety. You may be placed into a PTSD, GAD, or healthy control group based on questionnaire scores.
Richmond, VirginiaAges 18–35 - NCT04922762Recruiting
Exercise program study for blood vessel function in mental health
This study looks at how an exercise program affects blood vessel function (“vascular function”) in people with certain mental health conditions, and compares them to people without those symptoms. It may help researchers understand whether exercise could improve heart and blood vessel health alongside mental health symptoms.
Richmond, VirginiaAges 18–35 - NCT04916327Recruiting
Exercise program study for mental health and blood vessel health
This study tests whether an exercise training program can improve how well your blood vessels work in people with certain mental health conditions. You may join as someone with PTSD, someone with generalized anxiety, or as a healthy control group.
Richmond, VirginiaAges 18–35 - NCT03883412RecruitingPhase 4
Exercise and liraglutide for type 2 diabetes
This study tests if combining exercise with a drug called liraglutide improves blood vessel health and insulin sensitivity in people with type 2 diabetes. It looks at whether these treatments work better together or alone.
Charlottesville, VirginiaAges 21–60 - NCT04715022RecruitingTeam says not enrollingPhase 1/Phase 2
Vitamin C study for insulin resistance in obesity
This early-stage study tests whether vitamin C (and possibly how your body uses it) affects blood vessel function in people with obesity and insulin resistance. You may be asked to stop certain supplements before starting so researchers can measure the effect more clearly.
Kansas City, KansasAges 35–65 - NCT04482374Recruiting
Puberty blockers and heart/metabolic health in teens
This study looks at how puberty suppression (puberty blockers) may affect heart health and metabolism in children who are early in puberty. It may help researchers understand who benefits most and what changes happen during treatment.
Aurora, ColoradoAges 9–14 - NCT04832009RecruitingEarly Phase 1
Test a way to improve blood vessel function with lifestyle
This early-phase study looks at whether a treatment can help reverse problems in blood vessels caused by high glucose (sugar) and blood fat signals. It may be a fit if you are generally healthy, have normal insulin and sugar levels, and have a stable weight.
Kansas City, KansasAges 18–79 - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT05289063RecruitingPhase 1
Study new sleep apnea and blood vessel function
This Phase 1 study looks at how blood vessel function is affected by obstructive sleep apnea in adults who are newly diagnosed and have not used CPAP. It may help researchers understand the early effects of sleep apnea and guide future treatments.
New York, New YorkAges 18 years+ - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT05965518Recruiting
High-intensity exercise for brain and blood-vessel health in HIV
This trial tests whether high-intensity exercise can improve blood-vessel health and brain function in adults with HIV who are not very active and have thinking/memory problems. If you qualify, you’ll be asked to safely complete exercise and other study assessments.
Birmingham, AlabamaAges 50 years+ - NCT03253705Recruiting
Donate small blood samples to study heart and inflammation health
This study collects small blood samples (and sometimes samples during treatment) to help researchers understand diseases involving the heart, inflammation, and blood vessel function. It may help improve future tests and treatments by giving scientists usable human data.
Bethesda, MarylandAges 18–100 - NCT04558450Recruiting
Study how COVID-19 affects blood vessel stiffness and aging
This study looks at how having COVID-19 may affect your blood vessels over the following months. It may help doctors understand long-term “vascular aging” and who is most at risk, based on how sick you were during your COVID illness.
NancyAges 18 years+ - NCT06687590Recruiting
Serranator POINT FORCE registry for leg and dialysis access
This registry study is following patients whose blocked leg or dialysis access arteries are treated with a special balloon (Serranator) that helps open the vessel. The goal is to see how well the device works in real-world use.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for vascular dysfunction?
- Yes. Clin2 currently lists 38 recruiting vascular dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vascular dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vascular dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.