Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06796309Recruiting
Testing a rural health app for seniors and shoulder pain
This study tests a digital tool (called TRAK) to improve healthcare quality and access in rural areas. It is for healthcare workers or patients who are seniors or have long-term shoulder pain.
MadridAges 18 years+ - NCT06797492Recruiting
Virtual Reality for Shoulder Problems
This trial tests whether virtual reality (a computer-made, 3D environment) can help people with shoulder problems recover better. You would use a VR headset for exercises, and the study will see if it improves your shoulder movement or pain.
Roma, ItalyAges 18–75 - NCT06799091Recruiting
Nerve stimulation for fibromyalgia relief
This trial tests whether a nerve stimulation technique can help reduce fibromyalgia symptoms. It is open to women with a confirmed diagnosis of fibromyalgia who have had symptoms for at least three months.
GizaAges 20–45 - NCT06801119RecruitingPhase 1
HN2301 for autoimmune diseases study
This trial tests a new mRNA treatment called HN2301 for people with autoimmune diseases like lupus, scleroderma, or rheumatoid arthritis. It aims to see if the treatment is safe and helps control the disease.
Hefei, AnhuiAges 18–69 - NCT06804564Recruiting
Cold vs warm water for muscle pain recovery
This trial compares cold water and warm water immersion to see which helps recover from muscle soreness after exercise. If you are a healthy young man with moderate muscle pain from working out, this study may help you recover faster.
Biała Podlaska, Lublin VoivodeshipAges 18–25 - NCT06805188Recruiting
Acupuncture for knee osteoarthritis
This study tests whether acupuncture can reduce pain and improve function for people with knee osteoarthritis. If you have had persistent knee pain and meet the age and health requirements, this treatment may offer relief without surgery or strong medications.
Nanchang, JiangxiAges 18–70 - NCT06805448RecruitingPhase 1/Phase 2
Stem cell treatment for dry mouth in Sjögren's disease
This trial tests if injecting fat-derived stem cells into the salivary glands can help relieve dry mouth in people with Sjögren's disease. It aims to improve saliva flow and reduce discomfort.
CopenhagenAges 18 years+ - NCT06806605Recruiting
3D computer planning for jaw surgery
This trial tests whether a full 3D computer-assisted approach helps better diagnose and correct jaw and facial deformities during orthognathic surgery. It may benefit patients who need surgery to realign their jaws.
Bologna, Emilia-RomagnaAges 18–60 - NCT06806774Recruiting
Daily living test for children with juvenile arthritis
This study tests whether a simple daily activities test works well for children and teens with juvenile idiopathic arthritis. It may help doctors better understand how the condition affects everyday tasks.
AnkaraAges 8–18 - NCT06807541Recruiting
Exercise for balance in knee osteoarthritis
This pilot study tests whether a group exercise program can improve balance for people with knee osteoarthritis. You would join supervised exercise classes to see if they help with stability and daily movement.
Chilliwack, British ColumbiaAges Any age - NCT06807853Recruiting
Tracking movement with a smartwatch for spine arthritis
This study uses a smartwatch to track your movement and give you exercise advice. It aims to help people with axial spondyloarthritis stay active and manage their condition.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06809543Recruiting
Testing Tropho Tend for painful rotator cuff tendinopathy
This study tests a product called Tropho Tend to see if it safely reduces pain and improves function in people with rotator cuff tendinopathy, a condition where the shoulder tendons are sore and irritated. If you have had shoulder pain for at least 6 weeks and it is at least a 4 on a 10-point scale, this trial might be a good fit.
Sassuolo, ItalyAges 18 years+ - NCT06812481Recruiting
Anticholinergic drugs and bone health in rheumatoid arthritis
This study looks at whether a type of medication (anticholinergic drugs) used for other conditions affects bone health in people with rheumatoid arthritis. It will help doctors understand if these drugs increase the risk of osteoporosis (weak bones) and if they should be avoided.
BalıkesirAges 18 years+ - NCT06813040Recruiting
TMS therapy for jaw and face pain
This trial tests if repetitive transcranial magnetic stimulation (a non-invasive brain stimulation technique) can reduce long-lasting jaw and face pain caused by temporomandibular disorders. It might help people who have had pain for over six months and rate their pain as high.
CoimbraAges 18 years+ - NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06813443Recruiting
Studying cardiomyopathy to find who needs a heart transplant
This study is looking at people with cardiomyopathy to understand which patients are most in need of a heart transplant. By joining, you will help doctors learn more about critical cases and improve care for heart muscle disease.
Bologna, Emilia-Romagna/BolognaAges 12 years+ - NCT06813495Recruiting
ACT for injury prevention in nurses and aides
This study tests a program called Acceptance and Commitment Therapy (ACT) to help nurses and nursing aides prevent injuries at work. If you work in a long-term care facility in specific areas of the US or Thailand, you may be able to join.
Bowling Green, OhioAges 18 years+ - NCT06816056Recruiting
Foot therapy for hemophilia ankle arthritis
This study tests if manual therapy can help patients with hemophilia who have arthritis in their ankle. It seeks to improve joint health and reduce pain.
MurciaAges 18–65 - NCT06817382RecruitingPhase 1
Gene therapy for young boys with Duchenne muscular dystrophy
This study tests a one-time gene therapy given by injection into the spinal fluid (intrathecal) for boys with Duchenne muscular dystrophy. It aims to see if the treatment is safe and how it spreads in the body, and may offer a new way to slow the disease.
Little Rock, ArkansasAges 2–4 - NCT06818552Recruiting
Vascular surgeon's role in orthopedic tumor surgery
This trial is looking at how a vascular surgeon can help during surgery for tumors that involve blood vessels. It may help people with bone or soft tissue tumors that are close to or wrapped around major blood vessels.
Bologna, ItaliaAges 18 years+ - NCT06819475Recruiting
Muscle health study for childhood leukemia survivors
This study uses imaging to look at how well the mitochondria (the tiny power plants inside your muscle cells) are working. It compares survivors of childhood leukemia who have low muscle mass to healthy volunteers, to understand muscle health and find ways to help.
Memphis, TennesseeAges 18 years+ - NCT06819683RecruitingPhase 1
Testing a new oxygen sensor in people with and without mitochondrial myopathy
This study tests a tiny sensor that measures oxygen levels in muscle. It will help researchers understand how oxygen is used during exercise. If you have mitochondrial myopathy or are a healthy volunteer, you might be able to join.
Philadelphia, PennsylvaniaAges 18–65 - NCT06820489Recruiting
Comparing gum and bone healing after implant placement
This study tests three different ways to rebuild gum and bone around a new dental implant placed right after a tooth is pulled. It may help if you need a front tooth, canine, or premolar removed and have enough bone for the implant.
Ghent, East FlandersAges 20 years+ - NCT06820515Recruiting
Blood disorder patient registry for all ages
This study is a registry (a large database) that collects information from people who have or may have a blood disorder. It helps researchers learn more about these conditions and improve care.
Hickory, North CarolinaAges Any age
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.