Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06823089Recruiting
Study of a new hip implant for cartilage repair
This trial tests a new implant called ReNew Hip Implant to repair damaged cartilage in the hip joint. It may be an option if you have hip pain that hasn't improved with other treatments like physical therapy or injections.
St Louis, MissouriAges 14–64 - NCT06823726Recruiting
Taekwondo for axial spondyloarthritis
This study tests whether Taekwondo (a martial art) can help people with axial spondyloarthritis, a type of arthritis that affects the spine and pelvis. It looks at pain, stiffness, and quality of life, and may offer a new way to stay active and feel better.
Wŏnju, Gangwon-doAges 19–59 - NCT06825650Recruiting
Turkish adaptation of a pain questionnaire
This study aims to adapt a questionnaire about pain into Turkish and check if it works well. Researchers want to see if the questions are understandable and reliable for people with certain types of pain.
Ankara, AltındağAges 18 years+ - NCT06827496Recruiting
Starting with oral antibiotics for kids' bone and joint infections
This study tests if starting treatment for uncomplicated bone or joint infections in children with oral (by mouth) antibiotics is effective. It focuses on kids who are not severely ill and do not have certain risk factors, and who can begin oral antibiotics right away or after a short course of IV (intravenous) antibiotics.
Copenhagen ØAges 3 months–17 years - NCT06828042RecruitingPhase 1/Phase 2
CAR-γδT cells for refractory autoimmune diseases
This trial tests a new type of immune cell therapy (CAR-γδT cells) that targets a protein called CD19 on your own B cells. It is for people with certain autoimmune diseases that have not gotten better with standard treatments. The goal is to see if this therapy can safely control the disease.
BeijingAges 18–80 - NCT06828159Recruiting
Can wild blueberries improve joint health?
This study tests whether eating wild blueberries can improve joint health in people with arthritis. You would eat blueberries or a placebo daily for several weeks to see if they help with pain and stiffness.
Oklahoma City, OklahomaAges 40–75 - NCT06829433Recruiting
Knee arthritis and walking study
This study looks at how people with knee arthritis or a knee replacement walk and move. It aims to find better ways to measure knee function and improve treatments.
Portsmouth, HampshireAges 40–85 - NCT06829875Recruiting
Access to muscle and joint therapy services
This study looks at how quickly people get appointments for muscle and joint problems. It includes patients waiting for foot therapy, occupational therapy, or physical therapy.
Cardiff, WalesAges 18 years+ - NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies
This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.
StrasbourgAges 1–17 - NCT06832852Recruiting
Comparing cost-effective care for muscle and joint pain
This study compares different models of care to find the most cost-effective way to treat common muscle and joint problems (like back, neck, knee, or shoulder pain). It looks at which approach works best for patients with persistent pain to guide future treatment decisions.
Québec, QuebecAges 18–65 - NCT06833489Recruiting
Using genetic testing to find answers for rare muscle diseases
This study looks at leftover muscle tissue from people who have had genetic testing for rare muscle diseases but didn't get a clear diagnosis. The goal is to use newer genetic analysis to find the cause of their disease.
MarseilleAges Any age - NCT06833749RecruitingPhase 2
Testing KBP-336 for knee osteoarthritis with obesity
This study tests an experimental medicine called KBP-336 for people with both obesity and knee osteoarthritis who still have significant knee pain despite standard treatments. It aims to see if KBP-336 can reduce pain and improve function.
BrnoAges 45 years+ - NCT06834230RecruitingPhase 4
Testing dotinurad for high uric acid in people with high blood pressure
This study tests a medicine called dotinurad to see if it helps lower high uric acid levels in people who also have high blood pressure. It may be an option if you have not taken uric acid lowering drugs recently or have been off them for over 27 days.
Saga, Saga-kenAges 20 years+ - NCT06837025Recruiting
Fascial manipulation for kids with cerebral palsy
This trial tests a hands-on technique called fascial manipulation to see if it improves movement and walking in children with cerebral palsy. It is for families living near Helsinki.
HelsinkiAges 7–14 - NCT06838143Recruiting
Ilaris real-world study for periodic fevers and sJIA
This study watches how people with certain periodic fever syndromes or a severe type of childhood arthritis (sJIA) do on the medicine Ilaris during their regular doctor visits. It collects information to see how well the medicine works in everyday care.
SeoulAges 2–100 - NCT06838702Recruiting
Liver transplant bone health study
This study collects information from people getting a liver transplant. It looks at bone health and mineral levels in the body to better understand how they change after transplant.
Bologna, BolognaAges 18 years+ - NCT06838793Recruiting
Comparing two nerve block methods for lung surgery
This trial compares two techniques for numbing the chest during lung cancer surgery to see which provides better pain relief. It may help patients recover with less discomfort.
New TerritoriesAges 18–80 - NCT06838884Recruiting
A 6-minute step test for people with rheumatoid arthritis
This study is testing a simple, 6-minute step test as a way to assess physical function in people with rheumatoid arthritis. The goal is to see if stepping in place can be a helpful alternative to walking tests.
Merkez, ElâzığAges 18 years+ - NCT06839469Recruiting
Walking study for rare muscle and nerve conditions
This study looks at how children and teens with Duchenne muscular dystrophy (DMD) or spinal muscular atrophy (SMA) walk, by having them do walking tests while wearing sensors. The goal is to find better ways to track how these diseases progress and how treatments work over time, without needing blood tests or scans.
Palo Alto, CaliforniaAges 5 years+ - NCT06841562Recruiting
Home Exercise and Anti-inflammatory Program for Early RA
This study tests if a home-based exercise program, combined with anti-inflammatory strategies, can help people newly diagnosed with rheumatoid arthritis manage their symptoms and improve health. It's a remote program, so you can participate from home.
Durham, North CarolinaAges 18 years+ - NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+ - NCT06844214RecruitingPhase 1/Phase 2
Gene therapy trial for myotonic dystrophy type 1
This trial tests a one-time gene therapy (SAR446268) for people with non-congenital myotonic dystrophy type 1. It aims to see if the treatment is safe and can improve muscle symptoms like stiffness and weakness.
Gainesville, FloridaAges 10–55 - NCT06844643Recruiting
Axial spondyloarthritis progression study in China
This study tracks how axial spondyloarthritis progresses over time in Chinese patients. It helps doctors understand the natural course of the disease and improve care.
BeijingAges 18 years+ - NCT06845553RecruitingPhase 2
Vutiglabridin for knee osteoarthritis: a phase 2 study
This trial tests an experimental pill called Vutiglabridin for people with knee osteoarthritis. It aims to see if the drug is safe and effective at reducing knee pain and improving function.
Seongnam-si, Gyeonggi-doAges 40–75
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.