Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07829484Recruiting
Exercise and olive oil for fall prevention in older adults
This study tests whether a home exercise program combined with daily extra virgin olive oil can reduce the risk of falls in older adults who are frail or at high risk of falling. It may help improve strength, balance, and overall health.
Pamplona, NavarreAges 75 years+ - NCT07827664Recruiting
How insomnia affects muscle pain from exercise
This study looks at how insomnia affects pain sensitivity and how much muscle pain people feel after exercise. It may help researchers understand the link between sleep and pain, which could lead to better treatments for people with insomnia.
Hong KongAges 18–60 - NCT07831200Recruiting
Taping and leg strengthening for knee pain
This study compares two types of tape (McConnell and Kinesio) combined with exercises to strengthen the hip and knee, to see which works better for people with pain in the front of the knee, especially when squatting or climbing stairs.
Islamabad, Punjab ProvinceAges 26–44 - NCT07828080Recruiting
Hip replacement using a newer stem design
This study looks at how well a newer type of hip replacement stem (called the Actis stem) works for people having their first hip replacement. It aims to see if this stem provides good outcomes for various hip conditions.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07826260Recruiting
Lumbar mobilization for back muscle stiffness
This study tests whether a single session of manual therapy on the lower back can reduce muscle stiffness. It may help healthy adults understand how this treatment works.
IzolaAges 18–45 - NCT07826546Recruiting
Back pain sensitivity as a predictor of recovery
This study looks at whether increased sensitivity to pain in people with chronic low back pain might predict how well they recover. It aims to help doctors understand which treatments might work best for each person.
MardinAges 18–65 - NCT07827898Recruiting
Understanding pain sensitivity in tennis elbow
This study looks at how the nervous system might become more sensitive in people with long-lasting tennis elbow (lateral epicondylitis). It uses ultrasound to examine the elbow and may help doctors better understand and treat this condition.
IstanbulAges 18–65 - NCT07833020Recruiting
Gyrotonic exercise for teens with lupus after intensive care
This study tests whether a special exercise program called Gyrotonic can help teenagers with childhood lupus recover after a stay in the intensive care unit (ICU). The exercises aim to improve strength and movement, which may be affected after such a serious illness.
Dokki, Giza GovernorateAges 13–17 - NCT07832929Recruiting
Alcohol injection for cervical disc herniation pain
This study tests a procedure where a special alcohol gel is injected into a damaged disc in the neck to relieve pain. It is for people with neck pain caused by a disc problem that has not improved with other treatments.
Vimercate, Monza E BrianzaAges 18–75 - NCT07827677Recruiting
Brain stimulation for muscle pain relief in people with insomnia
This study looks at whether different types of brain stimulation (called TMS) can help reduce the muscle pain triggered during a test. It is designed for people who also have insomnia, and who are otherwise healthy.
Hong KongAges 18–60 - NCT07826520Recruiting
Daily symptom tracking for fibromyalgia
This study tracks your fibromyalgia symptoms every day for a week to understand how they change and affect your daily life. It may help improve future care by showing how symptoms fluctuate.
MardinAges 18–65 - NCT07826650Recruiting
How acute pain affects sleep in people with insomnia
This study looks at how a short-term (acute) pain affects sleep quality in people who suffer from insomnia compared to healthy sleepers. Participation may help researchers understand the link between pain and sleep problems.
Hong KongAges 18–60 - NCT06320899Recruiting
Comparing different rods for lower back spine surgery
This study tests two types of rods (mid/high-flex vs low-flex) used during back surgery for people with degenerative spine problems in the lower back. The goal is to see which type helps reduce pain and improve movement better.
AarbergAges 18–99 - NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT06463847RecruitingPhase 1
Stem cell therapy for knee osteoarthritis
This trial tests a new stem cell treatment (UC-MSCs) for knee osteoarthritis. It aims to see if this treatment is safe and can help reduce pain and improve knee function.
Wuhan, HubeiAges 50–70 - NCT02355301Recruiting
Improve care for people with orthopedic (muscle or bone) problems
This trial aims to improve the quality of care for people with orthopedic problems, such as issues affecting muscles, bones, or joints. It may help by testing a way of delivering care more effectively.
BrusselsAges 1–90 - NCT07823387Recruiting
Bladder pressure changes during dialysis in intensive care patients
This trial aims to see how special dialysis treatment (called CRRT) changes the pressure inside your belly, which might help doctors make better treatment decisions. If you are in the intensive care unit and need this treatment, your participation could improve care for future patients with similar needs.
Bursa, BursaAges 18 years+ - NCT07817745Recruiting
Surgical treatments for muscle stiffness in children
This study looks at how well two surgeries help reduce muscle stiffness in children. It may help improve movement and comfort.
Boston, MassachusettsAges 6–25 - NCT07818343Recruiting
Comparing two knee replacement designs for revision surgery
This study compares two types of knee implants used when a previous knee replacement needs to be revised (re-done). It aims to see which design offers better outcomes for patients needing both parts of the implant replaced.
Washington D.C., District of ColumbiaAges 18–80 - NCT07820293Recruiting
Comparing two massage techniques for upper back muscle pain
This study compares two hands-on treatments for trapezius myalgia, a condition causing neck and upper back pain. The goal is to see which technique provides better relief for people with this type of muscle pain.
IslamabadAges 18–45 - NCT07824102Recruiting
Study of LH and hCG hormones in adults with hormone disorders
This trial looks at the role of two natural hormones, LH and hCG, in adults who are being checked for hormone-related conditions. It may help doctors understand your hormone health better.
HerlevAges 18–90 - NCT07821034Recruiting
Reiki therapy for women with fibromyalgia
This study tests whether Reiki, a gentle hands-on healing technique, can help reduce pain and improve well-being in women with fibromyalgia. Participants will receive Reiki sessions and their symptoms will be tracked over time.
Diamantina, Minas GeraisAges 18 years+ - NCT07817537RecruitingEarly Phase 1
Comparing two ways to give tranexamic acid during hip replacement
This study compares two ways of giving a medicine called tranexamic acid (which helps reduce bleeding) during total hip replacement surgery. The goal is to see which method is better at reducing blood loss during and after the operation.
AlexandriaAges 18 years+ - NCT07825506Enrolling by invitation
Nerve glide exercises for fibromyalgia pain and daily function
This study tests whether adding gentle nerve glide exercises to standard care can reduce pain and improve everyday function in women with fibromyalgia. It may offer a non-drug way to feel better.
Santiago, Santiago MetropolitanAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.