Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,832 recruiting studies in this area right now.
By phase
- Not applicable3,967
- Phase 2222
- Phase 4195
- Phase 1191
- Phase 3151
- Phase 1/Phase 273
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis141
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee73
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain34
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California208
- New York94
- Florida80
- Arizona76
- Massachusetts76
- Maryland73
- Texas64
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,832 total
- NCT06880497Recruiting
Comparing knee sounds after two types of knee replacement
This study compares how much noise the knee makes (and how it feels to the patient) after two different kinds of total knee replacement surgery. It aims to help patients know what to expect after surgery.
AuxerreAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06792305Recruiting
Surgery order for severe pelvic fractures
This study tests the best order of steps during surgery to fix a severe pelvic fracture (Tile C1.2 or C1.3). It may help determine if stabilizing the back or the front of the pelvis first leads to better outcomes.
CairoAges 18–60 - NCT06794294RecruitingPhase 1/Phase 2
Stem cell therapy for chronic shoulder pain from partial rotator cuff tear
This trial tests whether a single injection of stem cells from donated umbilical cord tissue can help people with a partial rotator cuff tear that hasn't healed with standard treatments like physical therapy or injections. If you have had shoulder pain for at least 3 months and a partial tear confirmed by MRI or ultrasound, you may be eligible.
Seoul, KoreaAges 19 years+ - NCT06776562Recruiting
Corrective exercises for knee collapse in young women
This study tests whether specific corrective exercises can improve how your knees move when you squat or walk, focusing on women who have knee collapse (dynamic knee valgus) but no pain. If you qualify, you would attend supervised exercise sessions designed to strengthen and align your knees properly.
IstanbulAges 18–25 - NCT06769191RecruitingEarly Phase 1
CD7 car-t, stem cell transplant, and kidney transplant for SIOD
This trial tests a sequence of treatments for SIOD (a genetic condition causing immune and kidney problems). First, you receive CD7 car-t cells, then a stem cell transplant from a family donor, followed by a kidney transplant from the same donor. The goal is to see if this approach is safe and can help your body accept the new kidney.
Hangzhou, ZhejiangAges Any age - NCT06734949Enrolling by invitation
Computational models for neuromuscular disease
This study uses advanced computer models to better understand inherited neuromuscular diseases. It may help doctors find new ways to group patients and personalize care.
MunichAges Any age - NCT06772103Recruiting
Shoulder tendon surgery study
This study compares two ways to fix a specific tendon in the shoulder. It is for people who have a problem with that long tendon but do not have a full tear of the other important shoulder tendons.
AnnecyAges 40 years+ - NCT06777160Recruiting
Predicting bone cement risks with AI
This study uses artificial intelligence to predict a rare but serious reaction called bone cement implantation syndrome during hip and knee replacement surgeries. It may help doctors better prepare and protect you.
ErzurumAges 18 years+ - NCT06768762Recruiting
Home activity program for knee replacement recovery
This study tests a home-based physical activity program for adults who have had a knee replacement at least a year ago. It aims to help you become more active with remote support and coaching.
Columbia, South CarolinaAges 18 years+ - NCT06761040Recruiting
Hip and foot strength training for overweight women
This study tests whether adding hip-strengthening exercises to foot-strengthening exercises helps overweight women with flat feet. If you have foot pronation and are in your early 30s, you may be able to join.
Lahore, Punjab ProvinceAges 30–35 - NCT06771050RecruitingPhase 4
Antibiotics and surgery for hip and knee joint infections
This trial tests different antibiotic types and durations, plus surgical approaches, for people with a current joint infection in a hip or knee. It aims to find the best way to treat the infection and prevent it from coming back.
Garran, Australian Capital TerritoryAges 18 years+ - NCT06726005Recruiting
3D jaw study for sleep breathing problems
This study looks at how a small lower jaw and large overbite relate to sleep-related breathing issues, using 3D scans and functional appliances.
Rijeka, Primorje-Gorski Kotar CountyAges 10–14 - NCT06758297Recruiting
AI motivational talk after knee replacement
This study tests whether an artificial intelligence-guided motivational conversation can help reduce fear of moving after knee replacement surgery, and improve how much you can move.
Samsun, SamsunAges 18 years+ - NCT06774547Recruiting
Early jumping exercises for leg tendon pain
This study tests whether adding jumping exercises early helps people with long-lasting leg tendon pain recover faster.
AalborgAges 18–50 - NCT06785207Recruiting
Testing a new 3D-printed scoliosis brace for teens and children
This study tests a new 3D-printed scoliosis brace that can be adjusted to have different levels of support in different areas. It may be more comfortable than traditional braces while still correcting spine curves, and it aims to help people who already wear a brace and have a curve between 20 and 40 degrees.
Houston, TexasAges 8–18 - NCT06709365Recruiting
Comparing two surgeries for complex ankle breaks in older adults
This trial tests two ways to fix complicated ankle and lower leg fractures in people over 65. It compares using a nail through the heel versus plates and screws to see which helps you heal and move better.
SohagAges 1–2 - NCT06754150Recruiting
Shoulder Innovations shoulder replacement registry study
This study follows people who have or will have a shoulder replacement using a Shoulder Innovations device. Researchers will collect information on how well the device works and how your shoulder feels over time.
Birmingham, AlabamaAges 18 years+ - NCT06670885Enrolling by invitation
New DNA test for joint replacement infections
This trial uses advanced molecular methods to better diagnose infections in hip or knee replacement joints. The goal is to find infections more accurately so you can get the right treatment sooner.
Milan, MilanoAges 18 years+ - NCT06688227Recruiting
Core Stability Training for Cricket Fast Bowlers
This study is testing whether core stability exercises can help cricket fast bowlers prevent back pain. It compares doing core exercises on their own versus combining them with regular training.
Lahore, Punjab ProvinceAges 18–28 - NCT06650046Recruiting
Topping-off technique for lower back arthritis
This trial tests a 'topping-off' surgical technique for people with arthritis and disc problems in the lower back. If you have tried 3 months of non-surgical treatments without success, this surgery may be an option to relieve pain and improve function.
Jinan, ShandongAges 18–85 - NCT06666127Enrolling by invitation
Muscle force and growth study
This study looks at how the force of your muscle contractions at different lengths affects muscle growth and strength. You will do leg exercises on a special machine to see how your muscles respond.
Vancouver, British ColumbiaAges 19–30 - NCT06647082Recruiting
Robotic exoskeleton and game-based therapy for kids
This study tests a robotic exoskeleton (like a wearable robot) combined with fun video game activities to help kids and young adults improve their walking. It is designed for people who have certain knee problems when they walk.
Atlanta, GeorgiaAges 4–21 - NCT06646536Recruiting
Anti-gravity treadmill for meniscus tear recovery
This trial tests whether walking on an anti-gravity treadmill helps people recover from a meniscus tear better than standard care. It may reduce pain and improve knee function.
Istanbul, EyupAges 18–40
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,832 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,923 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.