Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,832 recruiting studies in this area right now.
By phase
- Not applicable3,967
- Phase 2222
- Phase 4195
- Phase 1191
- Phase 3151
- Phase 1/Phase 273
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis141
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee73
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain34
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California208
- New York94
- Florida80
- Arizona76
- Massachusetts76
- Maryland73
- Texas64
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,832 total
- NCT06932380Recruiting
A study on a custom ankle implant for people aged 20-60
This trial is testing a custom-made implant called Episealer for people with a damaged spot of cartilage in their ankle that hasn't gotten better with other treatments. The goal is to see if the implant helps improve symptoms and holds up well for at least 2 years after surgery.
DrammenAges 20–60 - NCT06992375Recruiting
Shoulder manipulation study for volleyball players
This trial tests a shoulder manipulation technique in healthy volleyball players to see if it improves shoulder function and performance. It may help if you play regularly and haven't had recent injuries or surgeries.
GdanskAges 18–30 - NCT06964282Recruiting
Comparing Two Nerve Blocks for Hip Replacement Pain Relief
This study compares two types of nerve blocks (iliopsoas block and PENG block) to see which one provides better pain relief and recovery after hip replacement surgery. If you are having a hip replacement with spinal anesthesia, you may be a good candidate.
LiègeAges 18 years+ - NCT06935331Enrolling by invitationPhase 4
Opioid-free spinal fusion for teens with scoliosis
This trial tests a way to manage pain after scoliosis surgery without using opioid medications. It aims to see if patients can recover comfortably using only non-opioid pain relievers, which may help avoid opioid side effects and addiction risks.
Charlotte, North CarolinaAges 10–20 - NCT06910982Enrolling by invitation
Yoga and Mindfulness for Chronic Low Back Pain
This study tests whether a combination of yoga and mindfulness exercises can help reduce chronic lower back pain. It compares this program to usual care, and may be a good fit if your pain is bothersome but you are not too afraid that moving will make it worse.
Karachi, SindhAges 25–45 - NCT06987188Recruiting
Modified Pilates for balance and trunk control in children
This study tests whether modified Pilates exercises can help children with mild intellectual disability improve trunk control and balance. It aims to find a fun and effective way to support their physical development.
Lahore, PinjabAges 6–12 - NCT06971601Recruiting
Testing physical exams for kneecap fat pad syndrome
This study aims to find out if simple physical exam tests can accurately diagnose impingement of the fat pad behind the kneecap. You would get a clinical exam and an MRl to compare the results, so researchers can see which tests best identify the problem.
Saint-MauriceAges 18–70 - NCT06820528Recruiting
Thumb arthritis surgery: is in-clinic therapy needed?
This trial compares recovery after thumb joint surgery with or without in-clinic physical therapy. It aims to see if patients can recover just as well with home exercises alone, which could reduce travel and costs.
Columbia, MissouriAges 18 years+ - NCT06885411Recruiting
Hearing loss from metal-on-metal hip implants
This study looks at whether metal-on-metal hip replacements can affect hearing. It aims to understand if there is a link between these implants and hearing loss.
DelftAges Any age - NCT06887647Recruiting
Physical therapy with horses for kids with neuromuscular disease
This trial tests whether physical therapy sessions involving horseback riding can improve arm and hand function in children with neuromuscular disease. It may help kids who can follow simple directions and are comfortable around horses.
Missoula, MontanaAges 6–17 - NCT06839690Recruiting
Comparing two exercises for De Quervain tenosynovitis
This study compares two types of exercises (sub-maximal isometric training vs eccentric training) to see which one helps more with thumb pain and tenderness caused by De Quervain tenosynovitis. You may qualify if you have had thumb pain for at least 3 weeks and meet certain diagnostic tests.
Rawalpindi, Punjab ProvinceAges 21–50 - NCT06860750RecruitingPhase 3
SHR-1314 injection for active non-radiographic axial spondyloarthritis
This trial tests a new injection called SHR-1314 for people with active non-radiographic axial spondyloarthritis (a type of inflammatory arthritis that doesn't show on X-rays but causes back pain and stiffness). It may help reduce inflammation and improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06802289Recruiting
Preventing frailty by keeping seniors active in the hospital
This trial tests whether a mobility program helps older adults stay strong and avoid frailty during a hospital stay. If you are 50 or older and expect to be in the hospital for at least 3 days, this study may offer extra support to keep you moving.
Moncton, New BrunswickAges 50 years+ - NCT06886802Recruiting
Study of a new neck surgery for spinal stenosis
This study is looking at a new, less invasive neck surgery for people with cervical spinal stenosis (narrowing of the spinal canal in the neck). It tests whether this surgery helps relieve symptoms like pain, numbness, or weakness in the arms or legs.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT06888934Recruiting
Testing a new toe implant for arthritis and crooked toes
This study tests a new implant called Lync® to fix arthritis or crooked toes (like hammer, claw, or mallet toes). The implant helps straighten the toe bone and may reduce pain.
LyonAges 18 years+ - NCT06845696Recruiting
Comparing exercises vs. taping for forward head posture
This study compares two treatments—Brugger's relief exercises and kinesio taping—to see which one improves forward head posture better. Forward head posture means your head sits too far forward from your shoulders, which can cause neck strain.
Islamabad, FederalAges 20–40 - NCT06858293Recruiting
Imagining exercises to boost knee strength after ACL surgery
This study tests whether imagining yourself doing exercises can help you regain strength in your thigh muscle after ACL surgery, and if it's something people can stick with during physical therapy.
Milwaukee, WisconsinAges 18 years+ - NCT06833372Recruiting
Shock wave therapy for knee arthritis
This trial tests if shock wave treatment can reduce knee pain from osteoarthritis. It may help people with moderate knee arthritis who haven't had recent physical therapy or joint injections.
BariAges 45–80 - NCT06820736Recruiting
Comparing drain methods after low back surgery
This study compares two different methods of using a tube (drain) to remove fluid after low back surgery. It aims to see which drain technique leads to fewer problems or better recovery for people having one or two levels of back surgery.
Minneapolis, MinnesotaAges 18–70 - NCT06853756Recruiting
Comparing two airway devices in children having orthopedic surgery
This trial compares two types of breathing tubes (I-gel and Ambu AuraGain) used during anesthesia to see which one causes less air to enter the stomach. It is for children ages 2-12 having planned orthopedic surgery.
Tanta, El-GharbiaAges 2–12 - NCT06878794Enrolling by invitation
Bio glue for fixing knee meniscus tears
This trial tests a medical bio glue to repair a torn meniscus in the knee. It may be a good option if you have a single tear and are otherwise healthy.
Ningbo, ZhejiangAges 18–60 - NCT06888908Recruiting
Blood volume changes during hip replacement surgery
This trial measures how blood volume and fluids shift in the body during and after hip replacement surgery. It helps doctors better understand fluid management for patients having this procedure.
CopenhagenAges 18 years+ - NCT06830655Enrolling by invitation
Climbing performance and body factors study
This study looks at how mobility, balance, and fatigue affect climbing performance. If you are a healthy climber, you may help researchers understand what makes a better climber.
Gdansk, GdańskAges 15–45 - NCT06809231Recruiting
Long-term follow-up of CartiONE for knee cartilage repair
This study follows people who had CartiONE treatment for a knee cartilage lesion more than 6 months ago. Researchers want to see how well the treatment works and how safe it is over 1 to 13 years.
Ghent, Oost-VlaanderenAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,832 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,923 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.