Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07836751Recruiting
Eye-controlled device for neck weakness
This study tests a device that lets you control head and neck movements using your eyes. It's designed to help people with neck weakness (head drop) move their heads more easily by looking in the direction they want to go.
Salt Lake City, UtahAges 18 years+ - NCT07839195Enrolling by invitationPhase 2
Steroid injection after radiofrequency ablation for back and neck pain
This trial tests whether giving a corticosteroid injection right after a radiofrequency nerve ablation (a procedure that zaps nerve endings to reduce pain) can help prevent the temporary nerve irritation that sometimes happens after. It may help make your recovery more comfortable.
BangkokAges 18 years+ - NCT07839403Recruiting
Comparing two types of hip replacement for arthritis
This study compares two types of hip replacement surgery: a newer option that preserves more bone (ceramic hip resurfacing) and a standard total hip replacement. Participants will wear a small activity monitor to see how their activity levels change after surgery, which may help doctors understand which procedure leads to a more active recovery.
DanderydAges 18 years+ - NCT07841067Recruiting
3D-printed vs. milled plates for jaw surgery
This study compares two types of titanium plates (3D-printed vs. traditionally milled) used to hold the upper jaw in place after corrective jaw surgery. It aims to see which type is more accurate and reduces surgery time, which could mean a faster recovery for you.
Cairo, New Cairo, Fifth SettlementAges 18 years+ - NCT07834190Recruiting
Immediate effects of two types of back movement therapy for mid-back stiffness
This study compares two hands-on therapy techniques for people with stiffness and pain in the upper-to-mid back. It tests whether slow, consistent pressure or a gentle rhythmic movement works better right away to improve your back mobility and reduce pain.
Islamabad, Punjab ProvinceAges 25–44 - NCT07839065Recruiting
Back tissue thickness in women with fibromyalgia
This study uses ultrasound to measure the thickness of a layer of tissue in the lower back of women with fibromyalgia compared to healthy women. It aims to see if this tissue is different in fibromyalgia, which could help understand the condition.
Ankara, AnkaraAges 18–65 - NCT07834177Recruiting
Comparing two neck and spine movement exercises for chronic neck pain
This study compares two types of gentle neck and spine movements (called 'glides') to see which one works better for people with chronic neck pain related to 'upper cross syndrome' (a pattern of tight and weak muscles in the neck and shoulders). The goal is to find a more effective way to reduce pain and improve posture.
Islamabad, Punjab ProvinceAges 20–40 - NCT07841158Recruiting
Rebuilding jawbone for dental implants
This trial tests a new material to rebuild the jawbone where it has thinned out, so it can hold a dental implant. It may help people who need a stronger jawbone for tooth replacement.
Giza, Giza GovernorateAges 21 years+ - NCT07834840Enrolling by invitation
Diet education for gout patients on urate-lowering therapy
This trial tests whether extra diet advice helps people with gout who are already taking urate-lowering medicine. It might help them manage their condition better.
Suwon, Gyeonggi-doAges 19 years+ - NCT07835256Recruiting
Virtual reality training for rheumatology staff
This trial tests a training program that combines online learning with virtual reality to help healthcare providers in rheumatology improve their skills. It may benefit patients by ensuring their care team is well-trained in managing rheumatic conditions.
Leiden, South HollandAges 18 years+ - NCT07838558Recruiting
Comparing two muscle-relaxing exercises for lower back pain
This study compares two muscle-relaxing techniques to help people with lower cross syndrome, a common cause of low back pain and poor posture. If you join, you'll receive one of these physiotherapy approaches to see which works better for relieving your pain.
Islamabad, Punjab ProvinceAges 19–35 - NCT07839572Recruiting
Exercise effects on abdominal separation in seniors
This study looks at what causes the belly muscles to separate in older adults and whether specific exercises can help. If you join, you may help researchers find better ways to manage this condition.
Gdansk, PomeranianAges 60 years+ - NCT07837427Recruiting
Different water pressures during minimally invasive back surgery
This study compares two different water pressures used during a minimally invasive back surgery to see if one causes fewer complications and gives the surgeon a clearer view. It aims to help improve recovery and surgical outcomes for people with lower back problems.
Kunming, YunnanAges 18–75 - NCT06462768Recruiting
Study of immune cell activity in systemic sclerosis
This study looks at a specific type of immune cell activity (called neutrophil extracellular traps) in the blood of people with systemic sclerosis, other connective tissue diseases, and healthy volunteers. It aims to understand how these cells may be involved in the disease and could lead to better treatments.
ReimsAges 18 years+ - NCT05516381Recruiting
Navigation-assisted knee replacement with two alignment methods
This study tests a computer-guided technique for total knee replacement and compares two ways of aligning the new joint. It may help improve how accurately the surgery is done, which could affect comfort and function afterward.
BarcelonaAges 18 years+ - NCT05653102Recruiting
Collecting data on a knee replacement system after surgery
This study collects real-world health and surgery records to better understand how the Truliant total knee replacement performs. It may help doctors and patients by improving future guidance on this knee system’s safety and effectiveness.
Aurora, ColoradoAges 18 years+ - NCT06451510Recruiting
Knee osteoarthritis study in Northern Sweden
This trial studies knee osteoarthritis in people from Norrbotten, Sweden, who broke their tibial plateau between 2001 and 2015. It aims to understand how the injury affects the knee over time.
Luleå, Norrbotten CountyAges 18 years+ - NCT06257979Recruiting
Infection check during repeat rotator cuff surgery
This study looks for unexpected bacteria in the shoulder during repeat rotator cuff surgery. It aims to learn how often these hidden infections happen so doctors can better treat patients.
BeaumontAges 18 years+ - NCT05849961Recruiting
Follow-up study for an Exactech hip replacement
This study checks how people do after receiving a specific brand of hip replacement (Exactech Hip System). It looks at safety and outcomes using either new follow-up, past medical records, or both, to better understand how the device performs over time.
Tulsa, OklahomaAges 18 years+ - NCT06464757Recruiting
Laryngomalacia and breathing in children: before and after treatment study
This trial is for children with laryngomalacia (a floppy voice box) who have noisy breathing and trouble breathing. It will check how they are doing before and after treatment, and follow up for one year to see how their quality of life improves.
OsloAges 1 week–12 months - NCT06457776Recruiting
Jaw bone health in people taking bone-strengthening drugs
This study looks at how a specific jaw problem (osteonecrosis) may happen in people taking bone-strengthening medications. It aims to better understand and manage this side effect.
RomaAges 18 years+ - NCT07826546Recruiting
Back pain sensitivity as a predictor of recovery
This study looks at whether increased sensitivity to pain in people with chronic low back pain might predict how well they recover. It aims to help doctors understand which treatments might work best for each person.
MardinAges 18–65 - NCT07832929Recruiting
Alcohol injection for cervical disc herniation pain
This study tests a procedure where a special alcohol gel is injected into a damaged disc in the neck to relieve pain. It is for people with neck pain caused by a disc problem that has not improved with other treatments.
Vimercate, Monza E BrianzaAges 18–75 - NCT07831200Recruiting
Taping and leg strengthening for knee pain
This study compares two types of tape (McConnell and Kinesio) combined with exercises to strengthen the hip and knee, to see which works better for people with pain in the front of the knee, especially when squatting or climbing stairs.
Islamabad, Punjab ProvinceAges 26–44
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.