Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,832 recruiting studies in this area right now.
By phase
- Not applicable3,967
- Phase 2222
- Phase 4195
- Phase 1191
- Phase 3151
- Phase 1/Phase 273
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis141
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee73
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain34
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California208
- New York94
- Florida80
- Arizona76
- Massachusetts76
- Maryland73
- Texas64
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,832 total
- NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT06656182Recruiting
Mobilization techniques for scapulocostal syndrome
This trial tests two types of gentle joint movements (SNAGs and scapular mobilizations) to see if they reduce pain and improve shoulder and neck movement in people with scapulocostal syndrome. If you have chronic neck pain and trouble lifting your arm overhead, this study may help.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT06648070Recruiting
Exercises for Upper Cross Syndrome in IT Workers
This study compares two types of physical therapy exercises to see which helps IT professionals with Upper Cross Syndrome (rounded shoulders and forward head posture) feel better. If you qualify, you'll get free treatment and help improve your posture and pain.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT06671860Recruiting
Exercises and hands-on therapy for neck pain
This study tests whether combining eye exercises with hands-on therapy helps people with non-specific neck pain (pain not caused by a known injury or disease). It may help improve how your neck moves and reduce discomfort.
IstanbulAges 18–65 - NCT06683222Recruiting
How muscle and bone talk to each other in healthy women
This study looks at how signals from muscles affect bone health in women of different ages. It aims to understand why bone density changes over time.
MontpellierAges 20–89 - NCT06677749Recruiting
Muscle response to eccentric exercise trial
This trial studies how your muscles respond to a specific type of exercise that focuses on lengthening movements, like lowering a weight. It may help us understand how exercise keeps muscles healthy.
Winnipeg, ManitobaAges 18–35 - NCT06626503RecruitingPhase 3
Pain medicine study for children having spine surgery
This study tests a pain medicine (methadone) for children and teens having spine fusion surgery for scoliosis. It aims to see if it helps control pain safely.
Cincinnati, OhioAges 10–18 - NCT06538792Recruiting
Proprioception and strength after ACL reconstruction
This study looks at how well people regain body awareness, muscle strength, and fear of movement after ACL knee surgery. It may help understand recovery patterns in the first year after surgery.
IstanbulAges 18–35 - NCT06580899Enrolling by invitationPhase 4
Knee pain pump study for single knee replacement surgery
This study tests whether a small pain pump placed in your knee joint during surgery can help control pain after a single knee replacement. It is for people who are having outpatient knee replacement surgery and have not been taking strong pain medicines recently.
Charlotte, North CarolinaAges 18 years+ - NCT07255248RecruitingPhase 4
Knee fat pad pain study for young female athletes
This study tests a treatment for knee fat pad pain in teenage girls who play organized sports. It aims to see if a specific injection helps after physical therapy hasn't worked.
Norwood, MassachusettsAges 12–18 - NCT06542705Recruiting
Internal brace for ACL reconstruction with BTB graft
This trial tests whether adding an internal brace (a strong suture tape) during ACL reconstruction with a BTB graft helps improve knee stability and recovery. It is for people ages 18 to 35 with a first-time ACL tear who are otherwise healthy.
New York, New YorkAges 18–35 - NCT06525532Recruiting
Tracking reabsorbable implant for flatfoot in kids
This study tracks how well a special reabsorbable implant works over time in children and teens who had subtalar surgery for flatfoot. You'll have an MRI to see how the implant has changed and if it helped your foot.
BolognaAges 8–15 - NCT06536777Recruiting
Shoulder exercises with and without blood flow restriction for cricket players
This study tests special arm and shoulder exercises (called Ballistic Six) with or without a blood flow restriction band to see which helps cricket players improve performance and prevent injury. You may be able to join if you're a male cricket player between 18-25, with no current shoulder problems.
Bahawalpur, Punjab ProvinceAges 18–25 - NCT06536790Recruiting
Strength training study for male basketball players
This study compares two types of strength training (hang clean and half squat) to see which is better for male basketball players. It might help improve your game if you are a healthy, experienced player.
Lahore, Punjab ProvinceAges 18–35 - NCT06534203Recruiting
Physical demands on caregivers in long-term care
This study measures the physical tasks and demands faced by full-time caregivers who work with residents in a long-term care facility. The goal is to help improve workplace safety and care quality.
Moncton, New BrunswickAges 19 years+ - NCT06544239Enrolling by invitation
Virtual reality training for basketball players with challenges
This trial tests if virtual reality exercises can help professional basketball players with physical or mental challenges improve their skills. It focuses on people who have uneven strength or movement between sides of the body.
Jinan, ShandongAges 17–29 - NCT06524843Recruiting
Evaluating fracture risk from cancer spread to bone
This study looks at people with cancer that has spread to the bones. It uses your medical imaging and records to understand your risk of bone fracture, without testing any new treatment.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06587048Recruiting
New bone window surgery for root canal infections
This trial tests a new way to perform root-end surgery using a special ultrasound device. It aims to treat infections at the tip of a tooth root by making a small opening in the bone, which may help you heal faster.
Rohtak, HaryanaAges 18–60 - NCT06432543Recruiting
Wear particle study in revision hip replacement
This study looks at tiny plastic particles that wear off from artificial hip joints over time. Researchers will study these particles from tissue taken during revision hip replacement surgery to understand how they affect the body.
Rochester, MinnesotaAges 20 years+ - NCT06449755Recruiting
Comparing nails and screws for a broken pinky knuckle
This study compares two types of surgery—using an elastic nail versus a screw—to fix a displaced pinky knuckle fracture. It aims to find which method helps heal better with fewer problems.
Istanbul, FatihAges 18–60 - NCT06474897Recruiting
Comparing mobilization and ozone therapy for shoulder pain
This study compares two treatments—gentle movement exercises and ozone injections—for shoulder pain. It aims to see which option helps people with shoulder impingement feel better faster.
ElâzığAges 18–65 - NCT06469346Enrolling by invitation
Eccentric Exercise vs. Stretching for Hamstring Flexibility
This study compares two ways to improve hamstring flexibility in men who are not very active: eccentric (lengthening) exercises vs. static stretching. If you have tight hamstrings and are a healthy university student, this trial may help you find which method works better.
Temuco, CautínAges 18–35 - NCT06415955Recruiting
Walking limits study for people with leg amputation
This study looks at what makes walking harder for people with a lower limb amputation. Participants will walk on a treadmill to help researchers understand these limits and improve rehabilitation.
Nîmes, GardAges 18–80 - NCT06421558Recruiting
Electrical stimulation for lower back nerve pain
This study tests whether a mild electrical stimulation applied to the lower back can help relieve pain from a pinched nerve. It involves weekly sessions for 6 weeks.
Escondido, CaliforniaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,832 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,923 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.