Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06689826Enrolling by invitation
Core Strength in Rotator Cuff Injury
This study looks at whether core muscle strength (the muscles in your belly and lower back) is affected in people with a partially torn rotator cuff in one shoulder. If you join, you will help researchers understand this connection, which might lead to better recovery programs.
Kırşehir, CentreAges 18–65 - NCT06686082Enrolling by invitation
Biologic therapy for early psoriatic arthritis
This study looks at whether starting biologic treatments early, even before joint pain appears, can help people with psoriasis who have signs of joint inflammation on ultrasound. You may be eligible if you have moderate to severe psoriasis but no joint symptoms yet.
Fuzhou, FujianAges 18 years+ - NCT06686017Enrolling by invitation
New bone graft for lower back fusion surgery
This trial studies a new bone graft material called Virtuos for use in lower back spinal fusion surgery. It may help patients needing a one or two-level lumbar fusion by providing a safe and effective option for bone healing.
South Bend, IndianaAges 18 years+ - NCT06677216Enrolling by invitation
Botox for jaw muscle pain study
This study tests if Botox injections can reduce pain in the jaw muscles caused by a jaw joint disorder (TMD). If you have this type of pain and are interested in Botox treatment, you may be able to join.
Utrecht, UtrechtAges 18 years+ - NCT06670651Enrolling by invitation
Study of a new total knee replacement system
This trial is testing a new knee replacement system called LinkSymphoKnee. It is for people needing a first-time total knee replacement to help reduce pain and improve function.
Birmingham, AlabamaAges 18–79 - NCT06662266Enrolling by invitation
Induce XT bone graft in foot and ankle fusion
This trial is testing a new bone graft material called Induce XT to help bones heal together during foot or ankle fusion surgery. It might be a good option if you have a missing piece of bone in your hindfoot or ankle and need a fusion to reduce pain and improve function.
Halifax, Nova ScotiaAges 18 years+ - NCT06658223Enrolling by invitation
Virtual reality for fibromyalgia pain
This trial tests if using immersive virtual reality can help reduce pain and improve well-being in people with fibromyalgia. If you have fibromyalgia and are over 18, you may be able to join.
Concepción, BiobioAges 18 years+ - NCT06623149Enrolling by invitation
Surgery vs. non-surgery for knee arthritis
This study compares non-surgical treatments with knee replacement surgery for people with knee osteoarthritis. It aims to find out which approach works better.
Copenhagen, CopenhagenAges Any age - NCT06606340Enrolling by invitation
Long-term study of eteplirsen, golodirsen, or casimersen for DMD
This study follows people with Duchenne muscular dystrophy (DMD) who are taking eteplirsen, golodirsen, or casimersen. It aims to understand how these medicines work in everyday life over a long period.
Little Rock, ArkansasAges Any age - NCT06605612Enrolling by invitation
Falls risk test for people with muscle and nerve conditions
This study is creating a test to predict falls in people with neuromuscular disorders. You will fill out a questionnaire about your fall risk.
München, BavariaAges 18–65 - NCT06591442Enrolling by invitation
Spinal Fusion Recovery in Older Adults
This study is looking at how older adults recover after spinal fusion surgery, a type of back surgery that connects bones in the spine. The goal is to find factors that help people heal faster and feel better afterward.
Wuhan, HubeiAges 60 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06576570Enrolling by invitation
Improving surgeon ergonomics with AI analytics
This trial uses AI to analyze surgeon posture and movements during acute care surgeries, with the goal of improving ergonomics and reducing physical strain. It may help identify better surgical practices for both surgeons and patients.
Gainesville, FloridaAges 18–99 - NCT06571565Enrolling by invitationEarly Phase 1
Manual lymph drainage for fibromyalgia patients
This trial tests whether manual lymph drainage (a gentle massage technique that helps move fluid in the body) can help reduce pain and other symptoms in women with fibromyalgia. It may offer a new, drug-free option to feel better.
Adana, çukurovaAges 25 years+ - NCT06549400Enrolling by invitationPhase 3
Study on long-term safety of mexiletine for myotonic dystrophy
This study tests if a daily capsule of mexiletine is safe and helpful over 26 weeks for people with myotonic dystrophy type 1 or 2. It's for people who finished a previous related study and want to continue treatment.
LeuvenAges 16 years+ - NCT06547762Enrolling by invitation
Hybrid rehab for kids with physical disabilities
This trial tests a hybrid approach to rehabilitation for children with physical disabilities, combining in-person and technology-based care. If your child gets outpatient therapy more than once a week and can follow instructions with your help using a computer, this might be a good fit.
JerusalemAges 3–21 - NCT06534593Enrolling by invitation
Physical therapy for low back pain from disc herniation
This trial tests whether physical therapy can help people with a specific type of disc herniation (postero-lateral) by improving pain, stability, walking, and daily function. It may be a good fit if you have low back pain that spreads to your leg or stays in your back.
Islamabad, FederalAges 18–50 - NCT06522321Enrolling by invitationPhase 2
Bone graft with platelet gel for immediate dental implants
This trial tests whether adding a special platelet-rich fibrin (I-PRF) to a standard bone graft (FDBA) helps preserve bone around dental implants placed right after a tooth is pulled. If you have a damaged single-rooted tooth and are in good health, you may be able to join.
Bengaluru, KarnatakaAges 18–55 - NCT06509776Enrolling by invitation
Bone growth and hormone health in young adults
This study looks at how bones mature and how hormones change as you become a young adult. If you were born in Denmark in 2006 or 2007 and are 18, you may be invited to help researchers understand these changes.
AalborgAges 18–19 - NCT06505135Enrolling by invitationPhase 1
Stem cells for rotator cuff tear repair
This study tests whether injecting your own stem cells (taken from belly fat) during rotator cuff repair helps the tendon heal better and reduces pain. It's for people with a recent, repairable tear who are otherwise healthy.
Sønderborg, DanmarkAges 40–69 - NCT06498232Enrolling by invitation
Video game exercises after scoliosis surgery
This trial compares active video game-based exercises with standard stability training in teens who had surgery for severe scoliosis. It aims to see if fun, interactive games can improve recovery just as well as traditional stability training.
IstanbulAges 10–18 - NCT06494670Enrolling by invitation
Trends in muscle and bone pain in U.S. adults
This study looks at how common different types of muscle and bone pain have been in U.S. adults over time. It uses data from a national health survey to understand trends, which may help improve pain care.
Ages Any age - NCT06491927Enrolling by invitation
Long-term follow-up for RGX-202 in Duchenne muscular dystrophy
This long-term follow-up study watches people who previously received the experimental gene therapy RGX-202 for Duchenne muscular dystrophy. It checks how patients are doing over time and does not involve any new treatment.
Little Rock, ArkansasAges Any age - NCT06478628Enrolling by invitation
Insomnia in pain rehabilitation patients
This trial looks at sleep problems in people going through pain rehabilitation. It aims to understand and possibly improve sleep in those with long-lasting pain.
RissaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.