Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06854913Enrolling by invitation
Shoulder Surgery and Sleep in Workers
This study looks at how shoulder surgery affects the sleep of people who do physical work. If you are having shoulder surgery, researchers want to see if your sleep changes after the operation.
Rome, ItalyAges 18 years+ - NCT06847776Enrolling by invitation
Study of a fracture liaison service after a fall-related break
This study follows patients who break a bone from a fall to see how well a fracture liaison service (a team that helps coordinate your care) can prevent future fractures and improve recovery.
Vandœuvre-lès-NancyAges 50 years+ - NCT06842017Enrolling by invitation
Shoulder exoskeleton trial for physically demanding jobs
This trial tests a wearable shoulder support device to help people with shoulder conditions do physically demanding jobs with less pain and strain. It may be a good fit if you have a shoulder problem and work in a job that requires frequent arm use.
Rome, ItalyAges 18 years+ - NCT06831331Enrolling by invitation
Diet and nutrition for newly diagnosed rheumatoid arthritis
This study tests whether a special diet can help manage symptoms of newly diagnosed rheumatoid arthritis. It aims to see if eating certain foods can reduce inflammation and improve your overall health.
GothenburgAges 18–85 - NCT06822933Enrolling by invitation
Remote monitoring study for gout patients
This study tests whether using a smartphone or tablet to monitor your gout from home can help manage the condition. You may qualify if you have had at least one gout flare in the last year and have high uric acid levels.
Oslo, Please SelectAges 18 years+ - NCT06819930Enrolling by invitation
Fibromyalgia fitness study for women aged 30-64
This study measures the functional capacity (daily movement and activity) of women with fibromyalgia compared to women without the condition. It helps understand how fibromyalgia affects physical fitness.
Barcelona, BarcelonaAges 30–64 - NCT06811363Enrolling by invitation
Bone's role in urine citrate levels
This study looks at how bones affect the amount of citrate (a natural substance) in urine. It may help doctors understand bone health in people with osteoporosis who haven't been treated yet.
Dallas, TexasAges 18 years+ - NCT06808386Enrolling by invitation
How often should you train for knee pain relief?
This study looks at how different training frequencies affect knee pain recovery. It may help active adults who have had front knee pain for at least three months.
São Paulo, São PauloAges 18–40 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT06786845Enrolling by invitation
Fibromyalgia and Sleep Disorder Treatment Study
This study tests a treatment for people with fibromyalgia who also have sleep problems. It aims to improve sleep and reduce pain.
UppsalaAges 20–70 - NCT06786754Enrolling by invitation
Skin cell study for Marfan syndrome and aortic aneurysms
This study looks at skin cells (fibroblasts) from people with Marfan syndrome or other genetic conditions that cause thoracic aortic aneurysms. The goal is to understand how these cells behave, which may help improve future treatments.
San Donato Milanese, MilanAges 18 years+ - NCT06779071Enrolling by invitationPhase 3
NPNP-001 injection for knee osteoarthritis pain
This study tests a new medicine called NPNP-001 for people with knee osteoarthritis who have not gotten enough relief from other treatments. The medicine is given as an injection into the knee to see if it can reduce pain and improve function.
SeoulAges 40 years+ - NCT06773923Enrolling by invitationPhase 3
3D-printed bone scaffold trial for dental implants
This trial tests a 3D-printed scaffold that dissolves over time to help regrow jawbone for dental implants. It is for people in Valdivia, Chile, who need bone buildup in the lower jaw.
ValdiviaAges 30–70 - NCT06763783Enrolling by invitationPhase 4
Shingles vaccine study for people with rheumatic diseases
This study offers the Shingrix shingles vaccine for free to adults with inflammatory rheumatic diseases. It compares how well the vaccine works in people taking immune-suppressing drugs versus those not taking them.
LundAges 18 years+ - NCT06762990Enrolling by invitation
Back and hip movement during Muslim prayer
This study looks at how the spine and pelvis move during common Muslim prayer positions. It might help if you are healthy, can pray comfortably, and want to help researchers learn more.
Asyut, Asyut GovernorateAges 18–55 - NCT06755957Enrolling by invitation
Wall angels for better posture in young adults
This study tests if adding 'wall angels' (a simple arm exercise) to standard exercises helps improve posture in young adults with a rounded upper back. It may help you stand straighter and feel better.
IspartaAges 18–30 - NCT06749509Enrolling by invitation
Musculoskeletal rehab courses and work ability study
This study looks at whether face-to-face or online rehabilitation courses help people with musculoskeletal disorders stay at work or return to work. It compares these courses to standard care.
HelsinkiAges 18 years+ - NCT06737601Enrolling by invitation
Shockwave or splint for trigger finger
This study compares two treatments for trigger finger: a special hand splint and shockwave therapy (a non-invasive treatment that uses sound waves to help the finger move smoothly). Researchers want to see which works better.
BariAges 18 years+ - NCT06726096Enrolling by invitationPhase 3
Trial of VDJ001 for moderate to severe rheumatoid arthritis
This trial tests a new medicine called VDJ001 for people with moderate to severe rheumatoid arthritis who are already taking methotrexate. The goal is to see if VDJ001 helps reduce joint pain and swelling better than a placebo.
Beijing, Beijing MunicipalityAges 18–75 - NCT06725199Enrolling by invitation
NMR metabolomic study in fibromyalgia
This study uses a special MRI-like test (NMR) to look at chemical changes in the body of people with fibromyalgia. It aims to better understand the condition and could help find new ways to diagnose or treat it.
Istanbul, IstanbulAges 18–65 - NCT06724497Enrolling by invitationPhase 1/Phase 2
Comparing 3D face scan methods for jaw surgery patients
This trial tests whether using a handheld 3D scanner is as accurate as a standard optical scanner for predicting soft tissue changes after corrective jaw surgery. It aims to find a more convenient and accessible way to plan surgery for patients with an underbite.
Cairo, Giza GovernorateAges 18–50 - NCT06709040Enrolling by invitation
Long-term safety of somapacitan in children with growth hormone deficiency
This study is watching children who are already taking somapacitan (a growth hormone injection) to see if it is safe over a long time. It collects information about growth and any side effects.
Glasgow, ScotlandAges Up to 18 years - NCT06696040Enrolling by invitation
Kinesiotherapy machine for leg stiffness and walking in neurological patients
This trial tests if a passive kinesiotherapy machine can improve leg stiffness (spasticity) and walking ability in people with neurological conditions like stroke or cerebral palsy. It may help those who have trouble moving their legs due to tight muscles.
Caxias do Sul, Rio Grande do SulAges 9 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.