Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,903 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,187
- Phase 1582
- Phase 3466
- Phase 1/Phase 2395
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,903 total
- NCT07225114RecruitingPhase 2
Better ultrasound imaging with contrast before biopsy
This trial tests a new, detailed ultrasound technique that uses a contrast agent (called Definity) to get clearer images of a suspicious area before a biopsy. It may help doctors better see the blood flow in the lesion, which could improve diagnosis.
Chapel Hill, North CarolinaAges 18 years+ - NCT07225309Recruiting
Meaning-Centered Therapy for Mexican Adults with Advanced Cancer
This study tests a therapy program called Meaning-Centered Therapy designed to help adults in Mexico with advanced cancer find meaning and improve their well-being. It involves sessions delivered by trained providers at the National Cancer Institute in Mexico (INCan).
New York, New YorkAges 18 years+ - NCT07226856RecruitingPhase 2
New combo for advanced pancreatic cancer
This trial tests a new drug (BMS-986340) plus standard chemo for people whose pancreatic cancer has spread or come back. The goal is to see if this combination works better.
Scottsdale, ArizonaAges 18 years+ - NCT07226869Recruiting
Computer-guided microwave ablation for liver cancer
This study tests a computer-guided microwave ablation procedure to destroy liver tumors. If you have early-stage liver cancer with up to 5 tumors, and one is 2-5 cm in size, you may be a candidate.
Boston, MassachusettsAges 18–90 - NCT07227636RecruitingPhase 2
Immunotherapy for ctDNA-positive colorectal cancer after surgery
This trial tests two immunotherapy drugs, botensilimab and balstilimab, for people with colorectal cancer who have had surgery and chemotherapy but still have detectable cancer DNA in their blood. The goal is to see if these drugs can help clear the remaining cancer cells.
Basking Ridge, New JerseyAges 18 years+ - NCT07229313RecruitingPhase 1
Testing KIVU-107 in advanced solid tumors
This trial tests a new drug, KIVU-107, for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if this drug is safe and helps shrink or control the cancer.
Santa Monica, CaliforniaAges 18 years+ - NCT07229768RecruitingEarly Phase 1
Study of 177Lu-CTR-FAPI for advanced solid tumors
This trial tests a radioactive drug called 177Lu-CTR-FAPI for people with advanced solid tumors that have not responded to standard treatments. It targets tumors that show a specific protein (FAP) on PET scans. The study focuses on certain cancers like pancreatic, breast, and soft tissue sarcoma.
ShanghaiAges 18–85 - NCT07229911RecruitingPhase 1
Study of TAK-781 in healthy people and PSC patients
This study tests an investigational drug called TAK-781 in healthy volunteers and in people with primary sclerosing cholangitis (PSC) who do not have cirrhosis. The study aims to see how the drug is processed by the body and whether it is safe.
Salt Lake City, UtahAges 18–68 - NCT07230262Recruiting
Robotic vs. laparoscopic surgery for IBD patients
This study compares two types of minimally invasive surgery—robotic and laparoscopic—for people with inflammatory bowel disease (Crohn's or ulcerative colitis) who need elective colon or rectal surgery. It aims to find out which approach might be better for recovery and outcomes.
Leuven, Vlaams BrabantAges 18 years+ - NCT07230509RecruitingPhase 2
Glue injection to prevent pancreatic leaks after Whipple surgery
This study tests injecting a medical glue into the pancreas during a Whipple procedure to see if it can prevent leaks. It may help people with a soft pancreas and small pancreatic duct.
Minya, Minya GovernorateAges 18–75 - NCT07231601Recruiting
Laparoscopic surgery for Crohn's disease of the small intestine
This trial tests a specific laparoscopic (keyhole) surgery technique for Crohn's disease affecting the last part of the small intestine. It aims to see if removing more of the fatty tissue around the bowel leads to better outcomes. If you have Crohn's disease needing surgery in this area, you may be eligible.
Piraeus, AtticaAges 16 years+ - NCT07232342Recruiting
Blood test for predicting sepsis outcomes after abdominal surgery
This trial tests whether a simple blood test (the capillary leak index) can help doctors better predict how sepsis will progress in people recovering from abdominal surgery. If you are in the ICU after surgery for an abdominal infection, this study may help guide your care.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07232407RecruitingPhase 1
Study of a radioactive drug for advanced solid tumors
This trial tests a new radioactive drug (Lutetium-177 BL-ARC001) for people with advanced solid tumors, including stomach, bowel, and other cancers. It aims to see if the treatment is safe and how well it works.
Chengdu, SichuanAges 18 years+ - NCT07232810Recruiting
Surgery With Extra Tissue Removal for Pancreatic Head Cancer
This study tests whether removing extra tissue around the pancreas during a standard surgery improves outlook for people with pancreatic head cancer. You may qualify if you have this type of cancer and are planning surgery without prior chemotherapy or radiation.
Minya, Minya GovernorateAges 18–80 - NCT07233447Recruiting
H. pylori and stomach cancer in the West Indies
This study looks at how common H. pylori infection is in people with stomach cancer in Guadeloupe. It may help doctors understand the link between this infection and stomach cancer in the region.
Baie-MahaultAges 18 years+ - NCT07234825Recruiting
Trial of dairy-free diet with liquid nutrition for eosinophilic esophagitis
This study tests whether a dairy-free diet combined with a special liquid nutrition drink (called Kate Farms) can help children and young adults with eosinophilic esophagitis (a condition where certain white blood cells build up in the esophagus and cause trouble swallowing, pain, or vomiting). The goal is to see if this combination can reduce symptoms and improve quality of life.
Seattle, WashingtonAges 1–21 - NCT07235007Recruiting
New treatment for bile duct cancer with heat, immunotherapy, and chemo
This trial tests a combination of heat therapy inside the bile duct (endobiliary RFA) with immunotherapy (durvalumab) and chemotherapy (gemcitabine and cisplatin) for people with unresectable extrahepatic cholangiocarcinoma. The goal is to see if adding the heat treatment improves outcomes.
AichiAges 18 years+ - NCT07235215Recruiting
Testing Vivatlac for Irritable Bowel Syndrome
This study tests a product called Vivatlac to see if it can help people with Irritable Bowel Syndrome (IBS). If you have moderate-to-severe IBS and haven't taken probiotics or antibiotics recently, you may be able to join.
JarocinAges 18–65 - NCT07235228Recruiting
Synbiotic supplement for irritable bowel syndrome
This trial tests whether a synbiotic (a mix of probiotics and prebiotics) called Vivatlac can improve gut health in people with moderate to severe irritable bowel syndrome (IBS). If you have IBS and are not already taking probiotics or antibiotics, you may be able to join.
JarocinAges 18–65 - NCT07235410Recruiting
Body composition study for liver cancer patients having TACE
This trial uses deep learning to analyze body composition from scans in people with hepatocellular carcinoma (HCC) who are undergoing TACE (a treatment that blocks blood flow to the tumor). It aims to predict outcomes better and may help doctors tailor care.
Wuhan, HubeiAges 18 years+ - NCT07235904RecruitingPhase 4
Mirikizumab vs standard treatment for newly diagnosed ulcerative colitis
This trial tests if starting with the stronger drug mirikizumab (top-down therapy) works better than the usual treatment with azathioprine for people newly diagnosed with moderate-to-severe ulcerative colitis. It aims to see which approach controls inflammation and improves symptoms faster.
KielAges 18–75 - NCT07236177RecruitingEarly Phase 1
Enzyme test for early breast, lung, or pancreatic cancer
This study tests a new blood test that measures enzyme activity to detect localized cancer. It is for people with newly diagnosed, untreated breast, lung, or pancreatic cancer, as well as healthy volunteers.
PoitiersAges 18 years+ - NCT07237438Recruiting
Comparing two anesthetics for muscle loss in colon surgery
This trial tests whether one type of anesthesia (TIVA) is better than another (balanced anesthesia) at preventing muscle loss in patients undergoing open colorectal cancer surgery. If you are scheduled for this surgery, your participation could help doctors learn which approach is gentler on your muscles.
IașiAges 18 years+ - NCT07237750Recruiting
Weight loss trial: endoscopy procedure vs lifestyle changes
This study compares a new endoscopic procedure (a stomach tightening treatment done through a tube in your mouth) with a structured diet and exercise program to help with weight loss. It is for Asian adults who have tried and failed to lose weight before.
Beijing, Beijing MunicipalityAges 18–65
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,903 recruiting gastroenterology studies from the U.S. registry right now, out of 12,451 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.