Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,908 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,188
- Phase 1584
- Phase 3466
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer492
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California463
- Arizona177
- Texas148
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,908 total
- NCT01102556Recruiting
Pancreas disease registry for people at risk or with pancreatic cancer
This study collects health information and stored samples (biospecimens) to learn more about pancreatic diseases, including cancer and early warning changes. It may help researchers understand who is at higher risk and improve future testing and care.
New York, New YorkAges 18–85 - NCT00991094Recruiting
Study follow-up after proton radiation treatment
This study collects information about both short-term and long-term side effects in people who receive proton radiation. It may help doctors better understand what happens to normal tissues over time and improve follow-up care.
Houston, TexasAges 18 years+ - NCT00899626Recruiting
Collecting stool and tissue markers from people with bowel conditions
This study collects samples (like tissue and other body fluids) from people who are getting a colonoscopy or similar camera test. It aims to find “biomarkers,” which are measurable signals that may help doctors better understand or detect bowel problems such as colorectal cancer, polyps, or inflammatory bowel disease.
Nashville, TennesseeAges 18 years+ - NCT02024542Recruiting
How the body changes after bariatric surgery
This study looks at how metabolism (how your body handles food and energy) responds after weight-loss surgery. It may help researchers understand what changes to expect in people with diabetes or prediabetes and cholesterol problems.
Sacramento, CaliforniaAges 18–55 - NCT01514045Recruiting
Gastric cancer registry for patients and certain family members
This study builds a registry (a secure database) to learn about people with gastric cancer, people at higher risk because of family history, and people with a specific inherited gene change. Being in the registry may help researchers understand causes and improve future care.
Stanford, CaliforniaAges 18 years+ - NCT00582621Recruiting
Family history study to support genetic testing research
This study collects family and medical history to better understand inherited causes of blood cancers (like lymphoma) and related conditions. It may help researchers build genetic findings that could improve how families understand their risk and future care.
Basking Ridge, New JerseyAges Any age - NCT02061306Recruiting
Study of gut microbes and genetics in infant celiac risk
This study looks at how gut bacteria, diet, and family background may relate to celiac disease risk in very young infants. It may help researchers understand why celiac disease happens and how it could be prevented or detected earlier.
Boston, MassachusettsAges Up to 6 months - NCT01731665Recruiting
Study of Crohn’s and ulcerative colitis in Seoul
This study looks at how inflammatory bowel disease (Crohn’s disease and ulcerative colitis) affects people in a specific area of Seoul. It mainly focuses on describing patterns and health needs rather than testing a new drug.
SeoulAges Any age - NCT02037867Recruiting
Study your liver blood markers if you’re at risk
This study looks at how certain blood tests (liver biomarkers) change in people with higher risk for liver disease. It may help doctors understand who is developing liver problems earlier and what patterns in blood tests matter most.
Nottingham, NottsAges 18 years+ - NCT00288119Recruiting
Study genes in Barrett’s esophagus and esophageal cancer
This study looks at genetic (inherited) factors that may be linked to Barrett’s esophagus and esophageal cancer. It may help researchers understand why these conditions happen in some families and others do not.
Baltimore, MarylandAges 18 years+ - NCT01561157Recruiting
Long-term study of inherited porphyria conditions
This study follows people with diagnosed porphyria over time to learn more about the condition using past and new lab (biochemical) and genetic (DNA) test results. It may help researchers better understand how porphyrias work and support future care.
Birmingham, AlabamaAges 1 minute+ - NCT00001276Recruiting
Understanding and Treating Severe Low Blood Sugar
This study helps doctors diagnose and treat dangerously low blood sugar, especially in people with pancreatic tumors that produce too much insulin. You'll receive comprehensive evaluation and personalized care to manage your condition.
Bethesda, MarylandAges 18–120 - NCT00904878Recruiting
Study of pregnancy outcomes for people with inflammatory bowel disease
This study looks at how pregnancy and newborn outcomes turn out for people with inflammatory bowel disease (IBD) who are pregnant and taking immune-suppressing medicines or biologic therapies. It may help doctors better understand risks and care for mothers and babies in similar situations.
San Francisco, CaliforniaAges 18–45 - NCT00360646Recruiting
Share records for a drug-related liver injury research registry
This study puts people with a past drug- or herbal-related liver injury into a research registry. The goal is to better understand why the injury happens so doctors can prevent and recognize it sooner.
Los Angeles, CaliforniaAges 2 years+ - NCT00843375Recruiting
Testing stool samples to find early colon cancer and polyps
This study checks stool samples to see how well stool tests can detect early colon cancer and precancerous growths called adenomas. If you qualify, you’ll collect stool samples for a lab test (FIT) and sometimes this helps sort who should get follow-up testing.
Los Angeles, CaliforniaAges 18 years+ - NCT01762813Recruiting
Study of blood/tissue markers in colorectal cancer surgery patients
This study looks at colorectal cancer patients who are planning curative surgery and collects related outcomes and lab “biomarker” information to better understand the disease. Your participation may help researchers connect test results to treatment results over time.
StavangerAges 18 years+ - NCT01280825Recruiting
Testing how to use genetic medicine results in routine care
This study looks at how to put genetic testing results (pharmacogenomics) into regular doctor care. It aims to see whether using the results helps doctors choose safer, better-matched medications.
Chicago, IllinoisAges 18 years+ - NCT01793831Recruiting
Fecal transplant study for people with Crohn’s disease
This study tests whether a standardized stool-based treatment (fecal microbiota transplantation) can help people with Crohn’s disease. You may qualify if your Crohn’s diagnosis has been stable and you’re willing to receive the fecal transplant.
Huai'an, JiangsuAges Any age - NCT01140789Recruiting
Study comparing people with and without bowel inflammation
This study looks at people with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) and compares them with people without it. Researchers want to understand differences that may help explain or better detect the disease.
Hong KongAges 18 years+ - NCT00001456Recruiting
Understanding Hermansky-Pudlak Syndrome: Research Study
This research study investigates Hermansky-Pudlak Syndrome (HPS), a rare genetic condition affecting blood clotting and skin color. Researchers are looking for people with HPS or their family caregivers to participate in clinical evaluations and questionnaires to better understand the condition.
Bethesda, MarylandAges 1 month–115 years - NCT00001532Recruiting
How Genes Affect Lung Disease Development
This research study examines how genetic factors contribute to various lung diseases, including alpha-1 antitrypsin deficiency, cystic fibrosis, and chronic obstructive pulmonary disease. Researchers want to understand why some people develop lung disease and how genetics plays a role, which may help improve treatment in the future.
Bethesda, MarylandAges 2–90 - NCT00260559Recruiting
Checks quality of life after esophagus surgery
This study looks at outcomes and quality of life after esophagus removal surgery, comparing minimally invasive surgery and open surgery. It may help doctors understand how different surgical approaches affect how you feel during recovery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT00900419Recruiting
Check biomarkers during bronchoscopy in breathing and throat pre-cancer
This study looks at “biomarkers” (measurable signals in samples) taken during bronchoscopy or related procedures in people with severe airway pre-cancer or certain lung/throat cancers, and in healthy volunteers. The goal is to better understand what these biomarkers mean and how they might help with diagnosis, staging, or monitoring.
Aurora, ColoradoAges 21–90 - NCT01789229Recruiting
Tumor and inflammation sample bank for one specific condition
This study builds a secure “tumor sample bank” using tissue collected from people who currently have one diagnosed condition, either cancer (malignant disease) or an ongoing inflammatory condition. Your samples could help researchers study your disease and develop better treatments in the future.
ViennaAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,908 recruiting gastroenterology studies from the U.S. registry right now, out of 12,480 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.