Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,908 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,188
- Phase 1584
- Phase 3466
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer492
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California463
- Arizona177
- Texas148
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,908 total
- NCT07385235RecruitingPhase 1
Safety and drug level study of AD-115 in healthy volunteers
This trial tests a new drug (AD-115A or AD-1151) in healthy volunteers to see how safe it is and how the body processes it. If you qualify, you'll receive a single dose and be monitored closely.
SeoulAges 19 years+ - NCT07385807Recruiting
Gut health and pregnancy in inflammatory bowel disease
This study looks at gut health in pregnant women with and without inflammatory bowel disease (IBD). It tracks a protein called calprotectin in stool samples, along with diet and baby health, to learn how IBD affects pregnancy and infant development.
Vancouver, British ColumbiaAges 19 years+ - NCT07387263Recruiting
Digital tool for genetic testing in cancer care
This study tests a digital tool that helps cancer doctors offer genetic testing to more patients. If you've already had genetic testing started by your oncologist, you may be able to join.
Toronto, OntarioAges 18 years+ - NCT07387185Recruiting
AI system for detecting chronic gut diseases
This trial tests an AI system to help detect and describe chronic diseases of the small intestine. If you are an adult having a small bowel endoscopy or capsule endoscopy, you may be able to join.
Pavia, PVAges 18 years+ - NCT07388459Recruiting
Study of autoimmune atrophic gastritis over time
This study follows people with autoimmune atrophic gastritis to understand how the condition changes over time and what symptoms or complications may arise. It aims to collect information that could improve future care.
Pavia, PaviaAges 18 years+ - NCT07388615RecruitingPhase 2
Echinacea for cryptosporidiosis in children with weak immune systems
This trial tests whether the herb echinacea (Immulant) can help treat cryptosporidiosis, a diarrheal infection, in children aged 5 to 12 whose immune systems are weakened. It aims to find a safe and effective treatment for these children.
CairoAges 5–12 - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07389161Recruiting
Nutrition and lifestyle triggers in IBD
This study looks at how diet and lifestyle may affect flare-ups in people with moderate inflammatory bowel disease (IBD). It aims to identify factors that can trigger symptoms.
MalmöAges 18–35 - NCT07389265RecruitingPhase 3
Continuing cetuximab after first treatment stops working for metastatic colorectal cancer
This trial tests if continuing the targeted therapy cetuximab after initial treatment stops working can help people with advanced colorectal cancer. Participants have a specific gene profile (RAS and BRAF normal) and their cancer responds well at first.
AnconaAges 18 years+ - NCT07389876Recruiting
Second-line treatment for advanced stomach cancer with nab-paclitaxel
This trial tests a new chemotherapy combination for patients with advanced stomach cancer that has worsened after initial treatment. It aims to find a better second-line option using a drug called nab-paclitaxel.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07390318Recruiting
Bowel continence study for people with spina bifida
This study looks at how bowel management enema programs work for people with spina bifida (a type of spinal cord condition). It aims to improve continence and quality of life.
Birmingham, AlabamaAges 5 years+ - NCT07390838RecruitingPhase 1
Study of SH009 for advanced solid tumors
This trial tests an investigational drug called SH009 for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and effective.
ShanghaiAges 18 years+ - NCT07391670RecruitingPhase 1
Testing subcutaneous durvalumab for lung and liver cancer
This trial tests a new way to give the immunotherapy drug durvalumab as a shot under the skin (subcutaneous) instead of through an IV. It is for people with certain types of lung cancer or liver cancer that has not spread widely and who have not had immunotherapy before. The goal is to see if the subcutaneous injection is safe and works similarly to the IV form.
FitzroyAges 18 years+ - NCT07391839RecruitingPhase 1
MDN-001 injection for liver cancer that can't be surgically removed
This trial tests an injection called MDN-001 for people with liver cancer (hepatocellular carcinoma) that cannot be removed by surgery or other local treatments. The goal is to see if it is safe and effective for patients whose cancer has not spread outside the liver.
Hefei, AnhuiAges 18–80 - NCT07393048Recruiting
Personalized ctDNA test to predict rectal cancer treatment response
This trial uses a personalized blood test (ctDNA-MRD) to see how well neoadjuvant therapy works for rectal cancer. If you have stage II or III rectal cancer that can be surgically removed, this study might help guide your treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT07395635Recruiting
Nutrition supplement study for liver surgery patients
This trial tests whether a special nutrition mix (immunonutrition) helps patients recover better after major liver surgery. You may be eligible if you are having a large liver tumor removed.
Mumbai, MaharashtraAges 18–90 - NCT07395778Recruiting
Feeding method after drainage of pancreatic necrosis
This trial compares two ways of feeding after a procedure to drain pancreatic necrosis: a tube placed into the small intestine or eating by mouth. It aims to see which method helps recovery better.
ChandigarhAges 18–75 - NCT07396662Recruiting
Pancreas Function and Recovery After Surgery
This study looks at how well the pancreas works (both hormone and digestive functions) and what happens to patients after pancreas removal surgery. It may help doctors better predict recovery and long-term health.
Taipei, TaiwanAges 20–75 - NCT01644903Recruiting
Checking biomarkers after a liver transplant
This study follows people who are getting a liver transplant (including repeat transplants) to monitor changes in their body using test results. It may help doctors understand how patients are doing after transplant and improve care over time.
Chicago, IllinoisAges 18 years+ - NCT01950572Recruiting
Biopsy study to learn about mesothelioma and related cancers
This study collects tissue samples (biopsies) and health information to better understand malignant mesothelioma and certain related solid tumors that may produce a protein called mesothelin. It may help future research and treatments, and you can only join if your diagnosis is confirmed and it’s safe for you to have the tissue taken.
Bethesda, MarylandAges 2–100 - NCT01757730Recruiting
MRI test to measure soft tissue stiffness
This trial uses a special type of MRI to estimate how stiff certain soft tissues are in the body. You may benefit by helping doctors better measure tissue stiffness, which can relate to different health problems.
Columbus, OhioAges 18 years+ - NCT01416714Recruiting
Tissue sample collection during cancer surgery or biopsy
This study is collecting tissue samples from people with certain cancers while they have surgery or a biopsy. It may help researchers learn more about these cancers and improve future diagnosis and treatment.
Chicago, IllinoisAges Any age - NCT01277419Recruiting
Study of new cases of several spine, joint, and eye diseases
This study enrolls people who have recently been diagnosed with certain inflammatory conditions affecting the spine, joints, or the eye. Researchers are looking to better understand how these illnesses start and how they may be linked, which could help guide future care.
BerlinAges Any age - NCT00061828Recruiting
Tracking Liver Disease in Newborns and Young Infants
This study follows babies under 6 months old who have early signs of liver disease (cholestasis) to better understand what causes it and how it progresses. Researchers will collect medical information over time to improve diagnosis and treatment.
Los Angeles, CaliforniaAges Up to 6 months
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,908 recruiting gastroenterology studies from the U.S. registry right now, out of 12,480 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.