Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,916 recruiting studies in this area right now.
By phase
- Not applicable4,936
- Phase 21,188
- Phase 1583
- Phase 3465
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer148
- Crohn Disease144
- Ulcerative Colitis140
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)107
- Liver Cancer101
- Lung Cancer99
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona174
- Texas148
- Florida135
- Massachusetts127
- Alabama123
- New York123
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,916 total
- NCT01617382Recruiting
Registering people getting heated chemotherapy into the abdomen
This trial is a registry study that follows people with certain abdominal (peritoneal) cancers who are planned for surgery plus heated chemotherapy placed inside the abdomen. It mainly helps doctors learn about outcomes and care patterns for these treatments.
Leuven, Flemish BrabantAges Any age - NCT01174121RecruitingPhase 2
Immunotherapy made from your tumor-fighting immune cells
This trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes, or TILs) for certain metastatic cancers. It’s designed for people whose cancer has not responded to standard treatments and who can safely provide a small tumor sample for cell-making.
Bethesda, MarylandAges 18–72 - NCT01365169Recruiting
How activity level and daily function relate to cancer survival
This study looks at how physical activity (movement during the day) and a clinician-rated “day-to-day function” score relate to overall survival in people with certain cancers. It may help doctors understand who benefits most from activity-focused care and better monitoring.
Houston, TexasAges 18 years+ - NCT01420562Recruiting
Posaconazole medicine study in transplant patients with mouth sores
This study looks at how posaconazole (an antifungal medicine) moves through the body in people who recently had an allogeneic stem cell transplant and have mouth sores (mucositis). It may help clinicians choose the safest and most effective dosing for preventing serious fungal infections.
Leuven, Vlaams-BrabantAges 18–75 - NCT01668186Recruiting
Study of how peroxisome disorders change over time
This study follows people with peroxisome biogenesis disorders (PBD) or closely related enzyme/protein defects to learn how symptoms and health changes over time. It may help researchers better understand the condition and plan future treatments.
Montreal, QuebecAges Any age - NCT01684904Recruiting
Proton beam radiation for certain esophagus cancers
This trial studies whether proton therapy can better treat early-to-mid stage esophagus cancer while aiming to reduce side effects to nearby organs. Proton therapy uses a targeted type of radiation, and participants are also checked to be eligible for curative surgery.
Loma Linda, CaliforniaAges 18 years+ - NCT01882205Recruiting
Testing new camera methods to find precancer in ulcerative colitis
This study compares different special camera techniques during colonoscopy to see which best finds early abnormal (pre-cancer) changes in people with long-term ulcerative colitis. It may help doctors improve how they screen and monitor your colon over time.
LeuvenAges 18 years+ - NCT01917552RecruitingPhase 3
Capecitabine pill treatment after stomach cancer surgery
This study compares taking capecitabine pills after curative surgery versus no further treatment. It aims to lower the chance of stomach cancer coming back in people with stage IB disease that has extra risk factors.
Seoul, Songpa-guAges 18–74 - NCT01935778RecruitingPhase 3
Extra chemo after stomach cancer surgery: compare two drug plans
This Phase 3 trial tests which combination of chemotherapy works better after surgery for stage IIIB/IV stomach or stomach–esophagus junction adenocarcinoma. Participants get randomized to one of two chemotherapy plans to see which helps people live longer and/or prevents cancer from coming back.
SeoulAges 20–75 - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT02206841Recruiting
Study to confirm fatty liver and build fibrosis test markers
This study enrolls people with confirmed fatty liver to help researchers create and validate tests that may estimate liver scarring (fibrosis). It focuses on collecting medical information and verifying the liver condition using lab/scan results, which could help improve future care.
SeoulAges 18 years+ - NCT02647879Recruiting
Preventing hepatitis C spread with treatment in Iceland
This study looks at giving hepatitis C treatment to people who test positive, to help prevent the infection from spreading. If you are 18 or older, live in Iceland, and can consent, you may be able to join.
ReykjavikAges 18 years+ - NCT02897908Recruiting
Noninvasive scan to check liver fat and scarring
This study tests a noninvasive FibroScan machine to help measure liver fat and possible liver scarring using information collected in a database. It may help researchers improve how liver problems like fat buildup and scarring are identified and tracked.
Buffalo, New YorkAges 18 years+ - NCT02530983Recruiting
Survey study for people after esophagus surgery
This study is a survey. It asks people about their experiences after esophagus surgery (either removing part of the esophagus or rebuilding it). It may help doctors understand what happens to patients over time and improve future care.
Rochester, MinnesotaAges 18 years+ - NCT02478892Recruiting
Screening study for pancreatic cancer in inherited gene risk
This trial tests ways to screen people who have a family-passed (inherited) gene mutation linked to higher pancreatic cancer risk. The goal is to find pancreatic cancer earlier and improve how screening is done for people at increased risk.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02270476Recruiting
Study of how cystic fibrosis lung disease changes over time
This observational study follows children newly diagnosed with cystic fibrosis to understand how their lung disease develops. It may help doctors better predict disease course and choose the right timing for care.
Heidelberg, Baden-WurttembergAges Any age - NCT02103361Recruiting
Pregnancy registry for Stelara or Tremfya exposure
This study is a pregnancy exposure registry. It collects information to better understand pregnancy outcomes after exposure to Stelara or Tremfya (medicines used for autoimmune diseases).
La Jolla, CaliforniaAges Any age - NCT02306382Recruiting
Study for diagnosing and treating perianal abscesses with surgery
This study focuses on people 18 and older who have a perianal abscess that needs surgical treatment. It aims to improve how these abscesses are diagnosed and managed, including care around surgery.
Umeå, County of Vasterbotten §Ages 18 years+ - NCT02107105Recruiting
Study how surgery affects life quality in rectal cancer
This trial studies how surgical treatment for rectal cancer affects patients’ quality of life and other day-to-day impacts. It may help doctors understand what to expect after surgery and how to better support patients.
Houston, TexasAges 18 years+ - NCT02417740Recruiting
Study of the natural course of noncirrhotic portal hypertension
This study follows people with noncirrhotic portal hypertension (NCPH) or people at risk for it to better understand how the condition progresses over time. It does not sound like a medication trial—more like careful monitoring to learn what happens in different people.
Bethesda, MarylandAges 12–100 - NCT02669992Recruiting
Compare closure methods for a loop ileostomy after rectal cancer
This trial studies which technique works best to close a loop ileostomy after rectal cancer surgery. It compares different closure methods to see which is safer and more effective for patients.
GothenburgAges Any age - NCT02518542Recruiting
POEM and stretching treatment for achalasia
This trial looks at a procedure called POEM, followed by prolonged stretching, to treat swallowing problems caused by specific esophagus muscle disorders. If you have the right diagnosis and can safely have an endoscopy, this may help improve how well food moves through your esophagus.
ViennaAges 18 years+ - NCT02139605Recruiting
Surgery type trial for stomach cancer after chemo
This trial studies which surgical approach (removing lymph nodes in a more limited vs more extensive way) works best for gastric cancer after you’ve already started chemotherapy before surgery. It’s aimed at improving cancer control while keeping the operation as safe as possible.
Mumbai, MaharashtraAges 18–85 - NCT02754115Recruiting
Audit of surgery with heated chemo for belly tumors
This study is an audit (a review of care) of patients who undergo cytoreductive surgery plus heated chemotherapy placed in the abdomen. It helps doctors understand how this treatment is done and what outcomes and safety it has.
Mumbai, MaharashtraAges 18–70
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,916 recruiting gastroenterology studies from the U.S. registry right now, out of 12,516 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.