Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT05920330Recruiting
Study of blocked noses and loss of smell
This study looks at people who have trouble smelling and also feel their nose is blocked. The researchers want to understand what causes these symptoms and how they might be related, which could guide better treatment.
Columbus, OhioAges 18–70 - NCT05922176Recruiting
Microneedle patch testing to predict allergy treatment response
This study uses a small microneedle patch to collect skin-related samples to help predict how well allergy immunotherapy may work. It includes people with house dust mite allergy and also a healthy control group, so researchers can compare biomarker results.
SeoulAges 19–60 - NCT05923203Recruiting
Testing combined hearing with cochlear implant and hearing aid
This trial studies a “combined” hearing approach that uses a cochlear implant plus low-frequency sound from a hearing aid. It may help people with different hearing profiles (including cochlear-implant users) hear more naturally by testing how well this combined setup works.
Edmond, OklahomaAges 5 years+ - NCT05929976Recruiting
Study of gut and blood chemistry in children with new leukemia
This study looks at the gut microbiome (tiny organisms in the gut) and metabolome (small chemicals in the body) in children and teens with newly diagnosed ALL. It may help researchers understand what is happening in the body early in treatment and could guide future, more personalized care.
New York, New YorkAges 3–18 - NCT05933889Recruiting
Study of robotic throat surgery for early oropharyngeal cancer
This study looks at how well different robotic surgery approaches work for people with early oropharyngeal squamous cell carcinoma (throat cancer). You may be asked for consent for extra tissue and imaging analysis to help researchers understand patterns related to outcomes.
LondonAges 18 years+ - NCT05935683Recruiting
Registry for severe, uncontrolled chronic sinusitis in Italy
This trial is a registry that enrolls people with severe, hard-to-control chronic sinusitis. It helps doctors better understand this specific type of inflammation and how it affects symptoms and quality of life.
Rozzano, MIlanAges 18 years+ - NCT05935618Recruiting
Occupational therapy rehab for frail older adults with swallowing trouble
This trial tests an occupational therapy–based rehabilitation program to help frail older adults with swallowing problems work more safely and comfortably. You may be considered if your swallowing screen results fall in a specific range and you can participate in the therapy and consent process.
HvidovreAges 65 years+ - NCT05936034Recruiting
Hearing aid vs no hearing aid during platinum chemotherapy
This study compares how patients’ quality of life changes when people who have hearing loss from platinum chemotherapy use a hearing aid versus not using one. It may help understand whether hearing aids improve daily life during treatment.
Vandœuvre-lès-NancyAges 18 years+ - NCT05938166Recruiting
Training foreign caregivers with an augmented reality system
This study tests whether an augmented reality (AR) training system can help foreign care workers learn how to provide care. It involves Indonesian caregivers training for caring for older adults in Kaohsiung, with tests based on the older adult’s ability to follow instructions.
Kaohsiung City, Sanmin DistAges 21–65 - NCT05941741RecruitingPhase 3
Tested low-dose radiation plus cadonilimab for nasopharyngeal cancer
This Phase 3 trial studies whether adding low-dose radiation to cadonilimab (an immune therapy) can improve outcomes for people newly diagnosed with a specific type and stage of nasopharyngeal cancer. If you’re eligible, it may offer a new treatment approach and helps researchers confirm whether it works best.
Guangzhou, GuangdongAges 18–70 - NCT05946057Recruiting
Registry study for people with otoferlin hearing loss
This study builds a patient registry and tracks the natural history of hearing loss in people whose genetic test shows changes in the otoferlin (OTOF) gene. It may help researchers understand how hearing symptoms progress over time and improve future treatments.
Goettigen, Lower SaxonyAges Any age - NCT05951478Recruiting
Study for people with primary ciliary dyskinesia follow-up
This study (RaDiCo-DCP) follows people who have a confirmed diagnosis of primary ciliary dyskinesia, a condition that can affect how your lungs clear mucus. The trial looks at long-term symptoms over time, which may help improve care planning and understanding of the condition.
BesançonAges Any age - NCT05955105RecruitingPhase 1/Phase 2
ILB-2109 plus toripalimab for advanced solid cancers
This Phase 1/2 study tests a combination medicine (ILB-2109) plus an immune therapy (toripalimab) in people with advanced solid tumors when standard treatments haven’t worked or aren’t available. It aims to find out if the treatment can shrink tumors and is safe enough to keep studying.
Jinan, ShandongAges 18–80 - NCT05955859Recruiting
Testing how to diagnose fungal sinus infections
This study looks at better ways to diagnose a fungal (mycotic) infection in the sinus/near-nose area. You may be considered if you have symptoms on only one side, such as blockage or drainage, and you can safely take part in the study tests.
Ostrava, Czech RepublicAges 18–80 - NCT05955469Recruiting
Test two cochlear implant sound-fitting methods
This trial compares two ways of setting up a cochlear implant for adults who need one and speak French. It may help find a fitting approach that gives clearer sound by using a “tonotopy-based” method versus a standard method.
Saint-EtienneAges 18 years+ - NCT05956587RecruitingPhase 2
Testing two study drugs for advanced lung cancer and other tumors
This Phase 2 study tests a combination of two experimental medicines in people with advanced or metastatic solid cancers, including non-small cell lung cancer and nasopharyngeal cancer. It aims to see whether the drugs can shrink tumors and improve outcomes, while carefully checking safety and eligibility.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05962359Recruiting
Personalized coaching for language in young children with hearing loss
This trial tests a language program designed for young children with hearing loss who are getting cochlear implants. It aims to improve how well children understand and use spoken language, by using a “prediction” approach to tailor support.
Chicago, IllinoisAges birth–5 years - NCT05970562RecruitingEarly Phase 1
Voice therapy plus biofeedback for vocal overuse problems
This early-phase study tests a mix of voice therapy and “biofeedback” (real-time feedback to help you change how you use your voice) for people with vocal overuse symptoms. It may help improve voice quality by targeting muscle tension and strain that happen when the voice is overworked.
Boston, MassachusettsAges 18–65 - NCT05983432RecruitingPhase 1
Study of BL-B01D1 for advanced lung and other solid tumors
This trial tests an experimental drug called BL-B01D1 for people with several types of advanced solid tumors, especially non-small cell lung cancer and breast cancer. It's designed for those whose cancer has continued to grow after standard treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT05985473Recruiting
AI speech enhancement for hearing aid improvement
This trial tests whether artificial intelligence can improve speech clarity in hearing aids for people with normal hearing or mild hearing loss. It may help if you have trouble understanding speech in noisy environments.
ParisAges 18 years+ - NCT05994170Recruiting
Lower radiation dose to tumor area for early nasopharyngeal cancer
This trial studies whether lowering the radiation dose to a smaller area around the tumor is safe and effective for people with newly diagnosed nasopharyngeal cancer that has not spread. It may reduce side effects while still curing the cancer.
Zhongshan, GuangdongAges 18–70 - NCT06001047Recruiting
Head acupuncture for BPPV residual symptoms
This study tests whether head acupuncture can help with lingering symptoms (like unsteadiness or discomfort) that sometimes remain after a successful repositioning procedure for BPPV, a common cause of vertigo. If you feel better but not fully steady, this treatment might help.
Xi'anAges 18–65 - NCT06001593RecruitingPhase 1/Phase 2
Electrical stimulation for Meniere's disease symptoms
This trial tests if a mild electrical current applied behind the ear can reduce dizziness and hearing problems in people with Meniere's disease. It may help those who still get vertigo attacks despite taking standard medications.
SeoulAges 19–80 - NCT06002984Recruiting
Nerve monitoring during thyroid surgery to protect your voice
This study tests a device that monitors a nerve near your voice box during thyroid surgery. The goal is to help protect your voice by giving the surgeon live feedback on the nerve's location and function.
SeoulAges 19–79
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.