Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06930560Recruiting
Hearing aids for dementia with mood or behavior issues
This study tests whether providing hearing aids to older adults with Alzheimer's or related dementias can reduce troubling symptoms like agitation or depression. If you have untreated hearing loss and a caregiver who can join you, this trial may help improve quality of life.
Baltimore, MarylandAges 60–100 - NCT06930781Recruiting
Study of Ponto implants outside of the operating room
This study looks at how well Ponto implants work when placed in a clinic or office setting instead of a hospital operating room. It is for adults who already had this procedure in 2019 or later.
Sacramento, CaliforniaAges 18 years+ - NCT06914908Enrolling by invitationPhase 2
Long-term safety study of lunsekimig for nasal polyps
This study tests the long-term safety and effectiveness of a medication called lunsekimig for people with chronic sinusitis and nasal polyps. It is for those who already completed a previous study on this drug.
La Jolla, CaliforniaAges 18 years+ - NCT06915454Recruiting
Better imaging during cancer surgery
This trial tests a high-resolution PET-CT scan done during surgery to help surgeons see exactly where the cancer ends. It may help make sure all cancer is removed while saving healthy tissue.
Nashville, TennesseeAges 18 years+ - NCT06914999RecruitingEarly Phase 1
Comparing a new scan to standard scan during head and neck cancer radiation
This trial is testing whether a newer type of PET/CT scan (F-18 NaF) can better detect blood vessel problems caused by radiation therapy than the standard scan (F-18 FDG) in people with head and neck cancer. If successful, it could lead to better ways to prevent and manage these complications.
Atlanta, GeorgiaAges 18 years+ - NCT06915038Recruiting
Measuring tumor DNA in blood for HPV-positive throat cancer
This study looks at a blood test that finds DNA from HPV-related throat tumors. It may help doctors decide on surgery and check if the cancer is completely removed.
Carmel, IndianaAges 18 years+ - NCT06919744Recruiting
Stenting for intracranial hypertension: early treatment study
This trial tests whether placing a small tube (stent) in a narrowed brain vein can help people with newly diagnosed intracranial hypertension (high pressure in the head) that causes vision problems. It is for those who have not yet taken standard medication and have specific vein narrowing seen on MRI.
MontpellierAges 18 years+ - NCT06912945Enrolling by invitation
Laser vs. standard tools for benign voice box growths
This study compares using two types of diode laser (980 nm and 450 nm) to traditional cold instruments for removing non-cancerous growths on the voice box. The goal is to see which approach works better based on the type of growth, patient factors, and laser settings.
Sohag, Sohag GovernorateAges Any age - NCT06901297RecruitingPhase 3
Raphamin for acute sinus infection in adults
This trial tests a new medicine called Raphamin for treating sudden sinus infection (acute rhinosinusitis) in adults. It compares the medicine to a placebo to see if it can reduce symptoms like facial pain and pressure when started within the first 2 days of illness.
AramilAges 18–75 - NCT06902623Recruiting
Less intense radiation for early HPV throat cancer
This study tries to see if less intense radiation can still work well for certain throat cancers linked to HPV. It is looking for people with early stage HPV-positive oropharynx cancer who may benefit from a lighter treatment plan.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06892340Recruiting
Testing a device to prevent motion sickness and disorientation
This study is testing a device that may help reduce motion sickness and feelings of disorientation. Healthy people who do not usually get motion sickness are needed to participate.
San Antonio, TexasAges 18–50 - NCT06894303Recruiting
Remote programming for cochlear implants in routine follow-up
This study tests if cochlear implants can be adjusted remotely (without visiting the clinic) during regular follow-ups. If you have a compatible implant and sound processor, you may be able to take part from home.
ParisAges 18 years+ - NCT06894927Enrolling by invitation
Hearing check for adults 50 and over
This trial offers a free hearing check for adults aged 50 and older. It aims to detect any hearing changes early and can help you understand your hearing health better.
Hradec Králové, Czech RepublicAges 50 years+ - NCT06893458Recruiting
Feeding and quality of life in children with a tracheostomy
This study looks at how feeding problems and quality of life affect children who have a tracheostomy (a tube in the windpipe). It aims to understand what difficulties children and families face, so care can be improved.
Solna, Stockholm CountyAges Up to 18 years - NCT06888219Enrolling by invitation
Acupuncture for Swallowing and Tube Removal After Brain Injury
This study tests if acupuncture on the ear and body can help people with severe brain injuries regain the ability to swallow safely and have their breathing tube removed. It's for patients who are at least 1 month but no more than 3 months after a stroke or brain bleed.
FlorenceAges 18 years+ - NCT06880367Recruiting
Sound training for tinnitus relief
This trial tests whether a sound-based training program (called Siopi) can reduce tinnitus. It uses brain wave recordings to see how the training changes brain activity.
OrléansAges 18–84 - NCT06882889Recruiting
Comparing domestic vs imported hearing aids for age-related hearing loss
This trial compares two types of hearing aids (one made in China, one imported) to see which works better for age-related hearing loss. You might benefit if you have moderate to severe hearing loss and are willing to test both devices.
Guangzhou, GuangdongAges 60–85 - NCT06883175Recruiting
New ways to measure how your esophagus works
This study uses special probes to measure the movement and pressure in your esophagus (the tube connecting your mouth to your stomach) to better understand swallowing problems like achalasia, GERD, and other conditions. The goal is to improve how doctors diagnose and treat these issues.
Chicago, IllinoisAges 18–85 - NCT06881368Recruiting
Understanding Susac syndrome in adults
This study looks at Susac syndrome, a rare condition that affects the brain, ears, and eyes. If you have hearing loss, vision problems, or confusion, researchers want to understand what causes it and how it affects people like you.
ParisAges 18 years+ - NCT06676722RecruitingPhase 2
SBRT and two targeted drugs for advanced nasopharyngeal cancer
This trial tests a combination of focused radiation (SBRT) and two targeted drugs (nimotuzumab and tislelizumab) for people with nasopharyngeal cancer that has come back or spread to a few spots (1-5) after prior immunotherapy. It aims to see if this triple therapy can help control the disease when standard treatment has stopped working.
Xiamen, FujianAges 18–75 - NCT06811844RecruitingPhase 2
Shorter chemo plus immunotherapy for advanced nasopharyngeal cancer
This trial tests a shorter course of chemotherapy combined with an immunotherapy drug (camrelizumab) for people with advanced nasopharyngeal cancer that hasn't spread to distant organs. The goal is to see if this approach works well while reducing treatment side effects.
Xiamen, FujianAges 18–65 - NCT06876506Recruiting
How B-cells relate to common allergies
This study looks at a type of immune cell (B regulatory cell) in the blood of people with and without allergies to pollens, house dust mites, or insect stings. It aims to help understand how these cells work in allergic disease.
Hull, East YorkshireAges 18 years+ - NCT06870292Recruiting
Nerve surgery for non-allergic rhinitis
This study tests a surgical procedure that cuts small nerves in the nose to relieve long-lasting, non-allergic nasal symptoms like stuffiness, runny nose, and sneezing. It may be an option for people with idiopathic rhinitis whose symptoms have not improved with other treatments.
Wuhan, HubeiAges 18–65 - NCT06876259Recruiting
AI tool to reduce antibiotics for young children with colds
This trial tests whether an artificial intelligence (AI) tool can help doctors decide when antibiotics are not needed for young children with colds. It aims to reduce unnecessary antibiotic use.
Pittsburgh, PennsylvaniaAges 6 months–2 years
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.