Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06876259Recruiting
AI tool to reduce antibiotics for young children with colds
This trial tests whether an artificial intelligence (AI) tool can help doctors decide when antibiotics are not needed for young children with colds. It aims to reduce unnecessary antibiotic use.
Pittsburgh, PennsylvaniaAges 6 months–2 years - NCT04708717Recruiting
Testing brain training for people with cochlear implants
This study focuses on people who already use cochlear implants and tests a way to improve how the brain processes sound timing. If you’re an adult cochlear implant user, you may be able to join and help researchers understand what works best for hearing.
Los Angeles, CaliforniaAges 18 years+ - NCT06857890RecruitingPhase 1
Safety study of Grammidin throat spray in healthy volunteers
This trial tests a new throat spray called Grammidin With Anesthetic to see if it is safe and how the body processes it. Healthy volunteers take the spray and are monitored for side effects and drug levels in the blood.
MoscowAges 18–45 - NCT06866418Recruiting
Phagenyx swallowing device registry study
This registry study looks at the Phagenyx system, a device that helps people with severe swallowing problems. It collects information from patients who are using the device or who need a feeding tube to see how well it works in real life.
Phoenix, ArizonaAges Any age - NCT06859281RecruitingPhase 1
Safety of Grammidin throat spray in healthy adults
This trial tests the safety and how the body processes a new throat spray called Grammidin. Healthy volunteers will use the spray so researchers can see how it works and if there are any side effects.
Saint PetersburgAges 18–45 - NCT06868433RecruitingPhase 1
TMV vaccine alone or with pembrolizumab for advanced HNSCC
This trial tests a vaccine made from your own tumor to help your immune system fight head and neck cancer that has returned or spread. It is given alone or with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors or slow progression.
Atlanta, GeorgiaAges 18 years+ - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT06860022Recruiting
Sentence Shaping for deaf or hard of hearing children
This trial tests a new way to help children who are deaf or hard of hearing improve their sentence writing skills. It focuses on children who use both spoken English and American Sign Language and need extra help with word order and grammar.
Nashville, TennesseeAges 9–15 - NCT06860152Recruiting
Improving speech understanding in noise with cochlear implants
This study tests how well people with cochlear implants can understand speech in noisy situations, compared to those with normal hearing. It involves a special imaging scan to see how the brain processes sound, which may help improve future implant technology.
Iowa City, IowaAges 18–99 - NCT06864273Recruiting
Pharmacy training to help with hearing aids in rural areas
This study trains pharmacy technicians in rural Alabama and Mississippi to help adults with mild to moderate hearing loss use over-the-counter hearing aids. It aims to improve access to hearing care in communities where it is limited.
Tuscaloosa, AlabamaAges 18 years+ - NCT06641687Recruiting
Sweet comfort for babies during nose scope
This study tests if giving a sweet solution (sucrose) to babies can make a flexible nose scope exam more comfortable. It may help reduce pain and stress during the procedure.
Toronto, OntarioAges 1 month–1 year - NCT06228079RecruitingPhase 3
Chemo-immunotherapy after surgery for early reoccurring nasopharyngeal cancer
This study looks at whether adding chemo-immunotherapy after surgery is better than surgery alone for patients whose nasopharyngeal cancer has returned but is still in early stages. It may help prevent the cancer from coming back again.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06857279RecruitingPhase 2
Testing HLX43 for advanced head and neck cancer
This trial tests an investigational drug called HLX43 for people with advanced head and neck cancer that has returned or spread. It aims to see if the drug can shrink tumors or slow cancer growth.
Jinan, ShandongAges 18–75 - NCT06850805RecruitingPhase 3
Nasal spray for teens with chronic sinusitis without polyps
This study tests a new nasal spray (OPN-375) for teens aged 12–17 with chronic sinusitis but without nasal polyps. It aims to see if the spray improves symptoms like congestion and runny nose.
Huntsville, AlabamaAges 12–17 - NCT06847217Enrolling by invitation
Does better mouth care help stroke patients with swallowing problems?
This study tests if improving oral hygiene can help stroke patients who have trouble swallowing. You'll practice swallowing exercises and see if mouth care makes them easier.
GhentAges 18 years+ - NCT06851663RecruitingPhase 2/Phase 3
New PET scan for many solid tumors
This trial tests a new type of PET scan that uses a special antibody to find a marker called Trop2 on many common solid tumors. It may help doctors see tumors more clearly without needing a biopsy.
ShanghaiAges 18–75 - NCT06852638RecruitingPhase 2
PET imaging for kidney cancer, lymphoma, and NPC
This study tests a new way to detect tumors by using a special injection that makes cancer cells visible on a PET scan. It may help people with renal cancer (especially clear cell type), lymphoma, or nasopharyngeal cancer.
ShanghaiAges 18–80 - NCT06856863Recruiting
Personality and learning esophageal voice after laryngectomy
This study looks at how your personality affects your ability to learn a special kind of voice (VOO) after larynx removal surgery. It aims to help doctors better support people learning this new way of speaking.
MarseilleAges 18 years+ - NCT06843018RecruitingPhase 2
Spray vs lozenge for sore throat from infection
This trial tests a new spray with anesthetic for sore throat caused by infections like pharyngitis. It compares the spray to a lozenge (Septolete Total) to see which works better and is safer.
Engel'sAges 18–75 - NCT06844071Recruiting
Safety of Sentio bone conduction implant in teens
This study tests the safety and performance of the Sentio bone conduction implant (a device that helps you hear by sending sound through the skull) in teenagers aged 12 to 17. It may be an option if you have certain types of hearing loss that cannot be helped by regular hearing aids.
Atlanta, GeorgiaAges 12–18 - NCT06839066RecruitingPhase 2
HLX43 for advanced nasopharyngeal cancer after prior treatments
This trial tests an investigational drug called HLX43 for people with nasopharyngeal cancer that has come back or spread, and who have already tried two or more prior treatments without success. The goal is to see if HLX43 can shrink tumors or slow the cancer's growth.
Fuzhou, FujianAges 18 years+ - NCT06840015Recruiting
Testing Airpod Pros as a hearing aid for mild to moderate loss
This study tests whether Apple Airpod Pros can work as an assistive hearing device for people with mild to moderate hearing loss. If you haven't used hearing aids before, you may be able to join and help find a new, affordable option.
Richardson, TexasAges 18–60 - NCT06830174Recruiting
tDCS Brain Stimulation for Laryngeal Dystonia
This study tests whether a gentle brain stimulation technique called tDCS can help improve voice control in people with laryngeal dystonia. It aims to find a new way to reduce muscle spasms in the voice box.
New Haven, ConnecticutAges 18–65 - NCT06830109RecruitingPhase 2
Testing a nasal spray for stuffy nose relief
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
St Louis, MissouriAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.