Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT04270734Recruiting
Brain-wave study of hearing timing from babyhood to adulthood
This study looks at brain activity (brain waves) when babies hear sounds with timing, and how that changes with age. It may help researchers understand early brain development in hearing and processing sounds.
AmiensAges birth–1 day - NCT04340024Recruiting
Testing blood markers linked to how well radiation works
This study looks for “biomarkers,” or measurable signs (often from blood or samples), that may show which cancers respond better to radiation therapy. It may help doctors choose radiation treatment more precisely, especially for people who had significant side effects before.
SingaporeAges 21–99 - NCT06959251Recruiting
Glycine and magnesium with thiamine for primary ciliary dyskinesia
This trial tests whether a combination of glycine, magnesium, and thiamine can help people with primary ciliary dyskinesia (a condition that affects the tiny hairs in your lungs). It aims to see if these supplements improve breathing and reduce lung problems.
Mexico CityAges 5 years+ - NCT06959082RecruitingPhase 2
Testing an experimental drug with chemoradiation for head and neck cancer
This trial tests an experimental drug called VS-101 combined with standard radiation and chemotherapy for people with advanced head and neck cancer that hasn't been surgically removed. The goal is to see if adding this drug helps the treatment work better while keeping side effects manageable.
New Haven, ConnecticutAges 18 years+ - NCT06958523Recruiting
Apple Health Study for US iPhone users
This study uses your iPhone and optional devices like Apple Watch to collect health data over time. It aims to discover how technology can help monitor and improve health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06953700Enrolling by invitation
Hearing and age study for adults with normal or mild hearing loss
This study looks at how differences in hearing between your ears affect your ability to hear in noisy places. Researchers want to learn more across different ages.
College Park, MarylandAges 18–80 - NCT06959108RecruitingPhase 2
Comparing two treatments for head and neck cancer before chemoradiation
This trial tests two different drug combos—one using an EGFR-targeted therapy alone, the other adding an immunotherapy—before standard chemoradiation for locally advanced head and neck cancer. The goal is to see which approach works better without prior treatment.
VillejuifAges 18–75 - NCT06955494Recruiting
Smartphone brain training for memory and hearing
This study tests whether a brain-training program done on a smartphone can improve hearing, thinking, and quality of life in people with mild memory problems and hearing loss. You and a family caregiver will use the program together.
Hong KongAges 60 years+ - NCT06960382RecruitingPhase 1/Phase 2
Cat allergy immunotherapy with lymph node injections
This trial tests a new way to treat cat allergies by giving tiny injections directly into a lymph node (a part of your immune system), instead of under the skin. It aims to see if this method is safe and can reduce cat allergy symptoms, even in people with asthma.
ZurichAges 18–65 - NCT06960616Recruiting
Fewer follow-ups after cochlear implant using a new mapping strategy
This study tests a new way to schedule follow-up visits after you get a cochlear implant. Instead of many routine check-ups, your device may be set using a special mapping strategy, which could save time and still keep your hearing working well.
Boston, MassachusettsAges 18–85 - NCT06002984Recruiting
Nerve monitoring during thyroid surgery to protect your voice
This study tests a device that monitors a nerve near your voice box during thyroid surgery. The goal is to help protect your voice by giving the surgeon live feedback on the nerve's location and function.
SeoulAges 19–79 - NCT06882980Recruiting
Comparing two sedatives for children's tonsil surgery
This study compares two sedative medications, ciprofol and propofol, for children (ages 3–11) during tonsil or adenoid removal surgery. It uses special brain-wave monitors (IoC1 and IoC2) to see which drug provides safer, more stable sedation.
Wuhan, HubeiAges 3–11 - NCT06950957Recruiting
Comparing two airway devices for septoplasty
This trial compares a video laryngeal mask with a breathing tube during septoplasty (nose surgery) to see which works better. If you are having this surgery, you may be able to join.
Samsun, IlkadimAges 18–65 - NCT06945848Recruiting
Stenting for Intracranial Hypertension on Acetazolamide
This trial tests whether placing a stent (a small tube) in a narrowed brain vein can help reduce pressure in the head in people with Intracranial Hypertension who have been on acetazolamide for over a year. It may be an option if you still have high pressure despite medication.
MontpellierAges 18 years+ - NCT06944795Recruiting
SWIR otoscopy for children getting ear tubes
This study uses a special type of otoscope (ear camera) to look inside the ears of children getting ear tubes. It will help doctors see if this new tool gives better images of the middle ear.
Palo Alto, CaliforniaAges 1–17 - NCT06321341RecruitingPhase 4
Testing Vespireit for chronic dizziness from autonomic dysfunction
This trial tests a new medication called Vespireit (prolonged-release buspirone) for people with chronic dizziness caused by a problem with the autonomic nervous system. The study aims to see if the drug helps reduce dizziness and improve quality of life.
BryanskAges 18–65 - NCT06936449Recruiting
Long-term follow-up of a cochlear implant that releases medicine
This study is checking how well a cochlear implant that slowly releases a medicine (dexamethasone) to reduce swelling works over a long time. It is for people who already took part in the main study for this implant.
Englewood, ColoradoAges 18 years+ - NCT06938542Enrolling by invitation
Palliative care needs for kids with rare diseases
This study asks children with rare diseases and their families about what kind of palliative care (comfort and support) they need. It aims to understand how to better help families through their child's illness.
Washington D.C., District of ColumbiaAges 1–99 - NCT06940505Recruiting
Follow-up from home for early larynx cancer
This trial tests if follow-up appointments from home, using video calls, work just as well as in-person visits for people treated for early-stage larynx cancer. It may save you time and travel.
Groningen, Provincie GroningenAges 18 years+ - NCT06940635Recruiting
Hand therapy for stroke: may help speech and swallowing
This study tests whether a special hand therapy using brain-computer interface and electrical stimulation can also help improve speech and swallowing problems after a stroke. You may be eligible if you're at least 3 months past your stroke, have some arm weakness, and have aphasia or dysphagia.
Innsbruck, TyrolAges 18 years+ - NCT06936501Recruiting
Cooling sensation drink test for safe swallowing after stroke
This trial tests a cooling sensation drink to help stroke patients with swallowing problems safely take a high-calorie, high-protein supplement. It looks at whether the cooling sensation makes swallowing easier and safer.
Málaga, MálagaAges 18–99 - NCT06940180RecruitingPhase 2
Immunotherapy and chemotherapy before surgery for sinus cancer
This trial tests a combination of an immunotherapy drug (toripalimab) plus chemotherapy before surgery for sinus cancer that has not spread. The goal is to see if this treatment shrinks the tumor so surgery can be more effective.
Boston, MassachusettsAges 18 years+ - NCT05578560Recruiting
Virtual reality rehab after vestibular schwannoma surgery
This trial studies whether virtual reality (VR) exercises can help people recover movement and balance after surgery for a vestibular schwannoma. If you’re eligible, you may be asked to use VR as part of your rehabilitation program.
PragueAges 18 years+ - NCT06930170Recruiting
Cochlear implant for children with hearing loss in one ear
This trial tests whether a cochlear implant helps children aged 4 to 6 years who have hearing loss in only one ear (or one ear with severe loss and the other with mild loss) improve their hearing and communication. The device is surgically placed in the ear with worse hearing.
ParisAges 4–6
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.