Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06298071RecruitingPhase 1
Peguricase with methotrexate for uncontrolled gout
This early-phase trial tests a new injectable medication (Peguricase) combined with methotrexate to lower uric acid in people with gout that standard pills haven't controlled. You would first take a low dose of methotrexate to check your tolerance, then receive Peguricase infusions while stopping your usual gout medications.
Bengbu, AnhuiAges 18–70 - NCT06310291RecruitingEarly Phase 1
VTP-1000 vaccine for adults with celiac disease
This trial tests an experimental vaccine called VTP-1000 in adults with celiac disease. It may help calm the immune system so that accidentally eating gluten causes fewer or less severe symptoms.
Los Angeles, CaliforniaAges 18–70 - NCT06309979Recruiting
Growth study for children with idiopathic short stature
This study tests whether an investigational drug can help children with idiopathic short stature (short height with no known cause) grow taller. It may be an option for children who are very short for their age and have not responded well to standard growth hormone therapy.
Phoenix, ArizonaAges 2–16 - NCT06303505RecruitingPhase 1/Phase 2
TUB-040 for advanced ovarian or lung cancer after standard treatments fail
This study tests a new drug called TUB-040 for people with ovarian cancer that has stopped responding to platinum chemotherapy, or with a type of lung cancer that has returned or spread. The drug is designed to target cancer cells and deliver a powerful anti-cancer agent directly to them, potentially slowing the disease.
Birmingham, AlabamaAges 18 years+ - NCT06305234Recruiting
Long-term immune response study for Palynziq PKU treatment
This long-term study checks how the immune system reacts to Palynziq (a treatment for PKU) over time. It involves extra blood tests for people already in another PKU study called 165-501.
Aurora, ColoradoAges Any age - NCT06314048Enrolling by invitation
Diabetes Support Program for Kids with Type 1
This study tests a program that helps kids and teens with type 1 diabetes use a continuous glucose monitor (CGM) and get remote check-ins from their care team. It aims to make diabetes management easier and more connected.
Palo Alto, CaliforniaAges 6 months–21 years - NCT06305273Recruiting
Face position study for obese patients during anesthesia
This study tests whether changing your head and body position helps with breathing mask ventilation before surgery in people with obesity.
Toronto, OntarioAges 18 years+ - NCT06298877Recruiting
Stoma reversal and quality of life in ovarian cancer
This study looks at how temporary stoma (a surgical opening in the belly) affects quality of life and recovery in women having surgery for ovarian cancer. It may help doctors decide when to reverse the stoma so you heal better.
Stockholm, SolnaAges 18 years+ - NCT06300450Recruiting
Alert test for cholesterol meds in PAD patients
This study tests whether a special alert in your electronic health record can help doctors start the right cholesterol-lowering medication for people with peripheral artery disease (PAD) who are not already on one. The goal is to see if the alert helps get treatment started more often.
Boston, MassachusettsAges 18 years+ - NCT06309576Recruiting
Study on body weight regulation using liquid meals
This study tests how the body regulates weight by having participants drink only a special liquid meal for two days. It may help researchers understand weight changes in people with low or high body weight.
Baton Rouge, LouisianaAges 18–40 - NCT06304428Enrolling by invitation
Preventing falls and fractures by optimizing medications in nursing homes
This study tests whether carefully reviewing and adjusting medications in a skilled nursing facility can help prevent future fractures and injuries in older adults who were recently hospitalized for a broken bone.
Boston, MassachusettsAges 65 years+ - NCT06296420Recruiting
Swallowing problems after thyroid surgery
This study looks at swallowing problems after thyroid surgery. It aims to understand how common these issues are and help patients recover better.
Milan, MIAges 18 years+ - NCT06309238Recruiting
Intensive diet vs. surgery for severe obesity
This study compares two programs for people with severe obesity: an intensive weight-loss diet and a weight-loss surgery (bariatric surgery). It aims to see which approach works better for long-term health.
AarhusAges 18–60 - NCT06297473Enrolling by invitation
Phone or video follow-up for pituitary tumor
This trial compares follow-up visits by phone or video to in-person checkups for people with non-functioning pituitary tumors. The goal is to see if remote checkups work just as well.
Køge, Region SjællandAges 18 years+ - NCT06295965Recruiting
Blood changes and cancer therapy study
This study looks at why some people develop blood disorders after cancer treatment. It monitors changes in blood cells to better predict and prevent these problems.
Seattle, WashingtonAges Any age - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06297980Recruiting
Periods, blood sugar, and exercise in type 1 diabetes
This study looks at how your menstrual cycle affects your blood sugar and how you respond to exercise if you have type 1 diabetes. It aims to help women manage their diabetes better throughout the month.
Aurora, ColoradoAges 18–45 - NCT06305299RecruitingPhase 1
CAR-T cell therapy for ovarian cancer
This trial tests a new treatment called CAR-T cells that target a protein called B7H3 found on cancer cells. It is for people with a specific type of ovarian, peritoneal, or fallopian tube cancer that has not responded well to platinum chemotherapy or has come back quickly.
Chapel Hill, North CarolinaAges 18 years+ - NCT06296992Recruiting
Type 1 diabetes, exercise, and mentoring study
This trial tests whether online mentoring can help adults with type 1 diabetes be more physically active. You'll get support to safely increase your daily activity and use your continuous glucose monitor (CGM).
Winnipeg, ManitobaAges 13–17 - NCT06298149Enrolling by invitation
Turtle Island Tales health program for families
This study tests a program called Turtle Island Tales for caregivers and young children living in certain high-poverty areas. It aims to see if the program helps families be healthier and happier.
Bozeman, MontanaAges 18 years+ - NCT06296550Recruiting
Digital diabetes education with real-time CGM
This study tests whether a digital diabetes education program plus a continuous glucose monitor (CGM) helps people with type 2 diabetes manage their blood sugar better. You'll get the CGM and educational messages on your phone, and researchers will see if it improves your health.
San Diego, CaliforniaAges 18 years+ - NCT06296485Recruiting
Safer Aging with Diabetes Monitoring
This study tests a way to help older adults with type 2 diabetes who use insulin avoid dangerously low blood sugar. You would use a continuous glucose monitor and get support via email or internet to stay safe.
Fremont, CaliforniaAges 75 years+ - NCT06310356Recruiting
Glucose sensor for gestational diabetes
This study tests whether a continuous glucose monitor (a small sensor that checks your blood sugar levels all day) can help women with gestational diabetes manage their blood sugar more easily. The goal is to see if it improves health for both mom and baby.
Sydney, CAMPBELLTOWN NSWAges 18 years+ - NCT06300047Enrolling by invitation
Diabetes transition support for young adults
This study tests a transition coordinator to help teens with type 1 diabetes move from pediatric to adult care. It aims to make the process smoother and improve health outcomes.
Calgary, AlbertaAges 17–18
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.