Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,640 recruiting studies in this area right now.
By phase
- Not applicable5,354
- Phase 2609
- Phase 1563
- Phase 3420
- Phase 4318
- Phase 1/Phase 2290
- Phase 2/Phase 386
Top conditions
- Obesity617
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes191
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome128
- Obesity & Overweight125
- Breast Cancer112
- Overweight105
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California524
- Maryland178
- Alabama175
- Arizona171
- Florida164
- Texas159
- Massachusetts151
- New York143
- Colorado115
- Pennsylvania114
Recruiting studies7,640 total
- NCT03538457Recruiting
Gastric bypass or sleeve surgery and paracetamol absorption
This study looks at how your body absorbs paracetamol (acetaminophen) after planned weight-loss surgery. It may help doctors better guide pain- and fever-medication dosing after gastric bypass or sleeve gastrectomy.
TrondheimAges 18–70 - NCT03519906Recruiting
Bariatric surgery study measuring how metoprolol is absorbed
This study looks at how metoprolol (a blood-pressure medicine) gets absorbed in the body before and after bariatric weight-loss surgery. If you’re preparing for gastric bypass or sleeve surgery, this may help researchers understand dosing and medicine absorption changes after surgery.
TrondheimAges 18–70 - NCT03535376Recruiting
Studies how valsartan works after bariatric surgery
This study looks at how the blood-pressure medicine valsartan is absorbed and processed in your body after gastric bypass or sleeve surgery. It may help doctors choose safer, more effective dosing after weight-loss surgery.
TrondheimAges 18–70 - NCT03538665Recruiting
Testing for endometrial and ovarian cancer using tampons
This study checks whether collecting samples using tampons can help detect endometrial and ovarian cancers in people who are already scheduled for certain gynecologic surgeries. It may help researchers improve future early detection tests.
Birmingham, AlabamaAges 18–99 - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT03532477Recruiting
Venlafaxine medicine study around weight-loss stomach surgery
This study looks at how the antidepressant venlafaxine is absorbed in the body when people undergo gastric bypass or sleeve gastrectomy. It may help doctors understand whether dosing should change after surgery.
TrondheimAges 18–70 - NCT03702309Recruiting
Banking and testing blood samples to study cancer
This study collects blood samples to “test and store” (bank) information that may help doctors understand cancer in the future. You might be able to join if you’re an adult with confirmed cancer or a higher-than-usual risk for cancer.
Toronto, OntarioAges 18 years+ - NCT03406611RecruitingPhase 1/Phase 2
Enzyme replacement for classical homocystinuria in children
This study tests a new enzyme replacement therapy called pegtibatinase for children with classical homocystinuria (HCU). The enzyme helps break down homocysteine, which may lower its levels in the blood and reduce symptoms.
Aurora, ColoradoAges 5–65 - NCT03412877RecruitingPhase 2
Personalized immune-cell therapy for advanced metastatic cancers
This trial tests a personalized cell therapy made from your own immune cells, changed to recognize “neoantigens” on cancer cells. It’s designed for people with metastatic (advanced spread) solid cancers or certain other cancers who have tried standard treatments but cancer is still growing.
Bethesda, MarylandAges 18–72 - NCT03407079RecruitingPhase 2
Study of sucralose’s effects on digestion of drugs
This study tests whether the sugar substitute sucralose changes how your body absorbs and breaks down certain medicines. You’d take sucralose or a placebo for 4 weeks, visit the clinic, and complete required samples and medicine doses during visits.
Bethesda, MarylandAges 18–60 - NCT03366168Recruiting
Using tongue tissue to grow stem cells in adults
This study takes a small sample from the front of your tongue to grow stem cells from your taste-bud tissue. It aims to understand whether this approach can be safely done in healthy adults and explore how the cells might be used in the future.
Baltimore, MarylandAges 18–120 - NCT03307304Recruiting
Studying different forms of childhood brain-wasting disease
This study looks at people with CLN3 and other related forms of NCL (a childhood brain-wasting illness) to better describe symptoms and disease changes over time. You may be followed with regular check-ins, medical records, and sometimes NIH visits or sample collection.
Bethesda, MarylandAges 1 week–100 years - NCT03374215Recruiting
Study hormone causes of high blood pressure in Black adults
This study looks at the body’s hormone signals to understand what causes primary aldosteronism (a condition that can lead to high blood pressure). By comparing clinical results and lab data, researchers hope to improve how the condition is diagnosed and managed, especially in Black participants.
Bethesda, MarylandAges 7–70 - NCT03472157Recruiting
Bariatric surgery for severe NASH with advanced liver scarring
This study tests whether bariatric surgery (either sleeve gastrectomy or Roux-en-Y gastric bypass) improves severe nonalcoholic steatohepatitis (NASH) with advanced liver scarring in people who are obese. You may also need liver biopsies to confirm your liver disease before and after treatment.
LilleAges 18–65 - NCT03451968Recruiting
Amino acid levels in long ICU stays after surgery or trauma
This study measures amino acids (building blocks from food) in people who are critically ill after surgery or trauma while they stay in the ICU for more than a week. It also compares results with healthy adults to better understand how critical illness affects nutrition needs.
Petah TikvaAges 18 years+ - NCT03448783Recruiting
Apixaban levels around bariatric surgery
This study checks how the blood-thinner apixaban behaves in your body before and after gastric bypass or sleeve surgery. Results may help doctors choose safer dosing around bariatric surgery.
TrondheimAges 18–70 - NCT03476525Recruiting
Study of fluoxetine after bariatric surgery
This study looks at how the antidepressant fluoxetine is absorbed and behaves in the body before and after gastric bypass or sleeve surgery. It may help doctors better predict how well fluoxetine works after weight-loss surgery.
TrondheimAges 18–70 - NCT03476538Recruiting
Study gabapentin levels after stomach bypass or sleeve surgery
This trial measures how the medicine gabapentin moves through your body after gastric bypass or sleeve gastrectomy. It may help doctors better choose doses for people taking gabapentin after weight-loss surgery.
TrondheimAges 18–70 - NCT03296826Recruiting
Study for women with BRCA gene changes
This study follows women who carry BRCA1 or BRCA2 gene variants (or a gene variant of unclear meaning) to learn about their risks over time. It may help improve how genetic information is used to guide future care.
OkayamaAges 20 years+ - NCT03449485Recruiting
Blood medicine study around weight-loss stomach surgery
This study looks at how a medicine (chlorprothixene) moves through the body before and after weight-loss surgery like gastric bypass or sleeve gastrectomy. It may help doctors understand the best timing and dosing of this medicine for people having these operations.
TrondheimAges 18–70 - NCT03446456RecruitingPhase 1/Phase 2
Vasopressin and pain perception study
This trial tests whether vasopressin, a nasal spray, changes how your brain processes pain. You will receive either the spray or a placebo and have an MRI scan to see brain activity.
Baltimore, MarylandAges 18–65 - NCT03440177Recruiting
Study medicine absorption after weight-loss stomach surgery
This study looks at how your blood pressure medicine (ramipril) is absorbed and handled by the body after gastric bypass or sleeve gastrectomy. It may help improve how these medicines are used after weight-loss surgery.
TrondheimAges 18–70 - NCT03492151Recruiting
Scans pancreatic cysts during a biopsy procedure
This trial tests a special camera (confocal laser endomicroscopy) used during an ultrasound-guided needle biopsy to help tell what type of pancreatic cyst is present. It may help doctors decide faster whether surgery is needed.
Scottsdale, ArizonaAges 18 years+ - NCT03334708Recruiting
Blood test study for pancreatic cancer
This study looks at blood tests to find markers that may help detect and monitor pancreatic cancer. It compares people with pancreatic cancer to those with benign pancreatic conditions and healthy volunteers.
Middletown, New JerseyAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,640 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,087 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.