Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07236762RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases like lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. It's for those whose disease hasn't improved with standard treatments.
BengbuAges 18–65 - NCT07236099RecruitingPhase 2
Study of ICP-332 for prurigo nodularis
This trial tests an experimental drug called ICP-332 for people with prurigo nodularis (a condition causing very itchy, hard bumps on the skin). It aims to see if the drug can safely reduce itching and improve skin lesions.
Birmingham, AlabamaAges 18–75 - NCT07236801RecruitingPhase 1
Cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with several autoimmune diseases that have not improved with standard medications. It aims to see if this treatment can help control the disease when other treatments have failed.
Xuzhou, JiangsuAges 18–65 - NCT06563401Recruiting
Heart health in adults with type 1 diabetes
This study looks at the long-term risk of heart disease and death in people diagnosed with type 1 diabetes as adults. Researchers will compare their health to people without diabetes to understand how type 1 diabetes affects the heart over time.
StockholmAges 18–110 - NCT07235683RecruitingPhase 4
Stronger CMV treatment for lung transplant recipients
This trial tests adding a drug called letermovir to standard antiviral therapy for lung transplant patients with CMV infection. The goal is to see if the combination helps clear the virus faster and more effectively.
Toronto, OntarioAges 18 years+ - NCT07230639RecruitingPhase 2
Shorter radiation with chemo and immunotherapy for high-risk colon cancer
This trial tests a shorter course of radiation combined with chemotherapy and an immunotherapy drug (PD-1 inhibitor) for people with a specific type of high-risk colon cancer that has not spread. The goal is to see if this approach can shrink the tumor before surgery and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT07236502Recruiting
Lifestyle program for people living with multiple myeloma
This study tests a lifestyle program that includes physical activity and nutrition guidance for people who have had multiple myeloma for at least a year. The goal is to see if this program helps improve quality of life and overall well-being.
Maywood, IllinoisAges 18 years+ - NCT07236684Recruiting
MS Bladder Control: Study of Muscle Activity
This study looks at how well the pelvic floor muscles work in people with MS who have bladder control problems. It may help find better ways to manage urinary incontinence.
IstanbulAges 30–50 - NCT07234487RecruitingPhase 2
Comparing two drug combos for advanced Hodgkin lymphoma
This trial tests a newer, lower-dose immunotherapy combination (AVD plus nivolumab) against a standard intensive chemo regimen (BEACOPP) that is adjusted based on PET scan results. It is for people with advanced classical Hodgkin lymphoma that has not been treated before.
MoscowAges 18–60 - NCT07235501Recruiting
Understanding immune cells after stem cell transplant
This study looks at immune cells in your blood and in tissues affected by chronic graft-versus-host disease (a condition where donor cells attack your body) after a stem cell transplant. By analyzing samples, researchers hope to better understand this condition and improve future treatments.
Duarte, CaliforniaAges 7 years+ - NCT07234747Recruiting
Core stability: exergaming vs. standard exercises for kids with JIA
This study compares two types of core-strengthening exercises for children with juvenile idiopathic arthritis (JIA). One group does standard core-stability exercises, and the other plays active video games (exergaming) that work the same muscles. The goal is to see which approach works better and is more fun for kids.
Istanbul, BuyukcekmeceAges 8–12 - NCT07236021Recruiting
e-Motion: emotion support for chronic cancer patients
This trial tests an online program called e-Motion that helps people with chronic cancer manage their emotions. It may help you feel more in control and better cope with your diagnosis and treatment.
Brussels, AnderlechtAges 18 years+ - NCT07239700Enrolling by invitation
Buzzy and TickleFlex for easier insulin shots in kids
This study tests two devices, Buzzy and TickleFlex, to see if they can reduce pain and fear during insulin injections in children with type 1 diabetes. It may help make daily injections more comfortable.
Hakkari, CentreAges 6–12 - NCT07239830Recruiting
Normal Interferon Levels in Healthy Adults 80+
This study aims to find normal levels of interferon (a natural protein that helps fight viruses) in healthy people aged 80 and older. It will help doctors better understand what is 'normal' for older adults.
VilleurbanneAges 80 years+ - NCT07231952RecruitingPhase 2
Study of pirtobrutinib, venetoclax, and rituximab for Waldenström's macroglobulinemia
This trial tests a combination of three targeted drugs for people with untreated Waldenström's macroglobulinemia (WM), a rare blood cancer. The drugs aim to shrink tumors and lower the abnormal antibody (IgM) that causes symptoms, potentially offering a new first-line treatment option.
Boston, MassachusettsAges 18 years+ - NCT07233642RecruitingPhase 1
Fast CD19 CAR-T therapy for lupus not helped by standard treatment
This trial tests a quick-made CAR-T cell therapy for children and adults with active lupus who haven't gotten better with standard drugs. The goal is to see if targeting a protein called CD19 on certain immune cells can calm the disease.
Hangzhou, ZhejiangAges 5 years+ - NCT07234019RecruitingPhase 2
Rituximab plus anti-CD38 antibody for ITP
This trial tests whether adding an anti-CD38 antibody to the standard drug rituximab works better than rituximab alone for adults with long-term immune thrombocytopenia (ITP) who have already tried steroids without lasting success.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07239856Recruiting
Goat vs. Cow Milk: Which is easier to digest?
This study compares how well people digest goat milk versus cow milk. If you have trouble with cow milk but not goat milk (or can drink both), researchers want to see if goat milk is a better choice for you.
BobignyAges 18–65 - NCT07238712RecruitingPhase 2
New drug combo for high-risk blood cancer transplant
This trial tests a new combination of two chemotherapy drugs (bendamustine and cyclophosphamide) given before a stem cell transplant to help prevent graft-versus-host disease. It is for people with high-risk blood cancers who don't have a fully matched donor and will receive a partially matched transplant.
Saint PetersburgAges 18–70 - NCT07232550Recruiting
Breathing study for children needing bronchoscopy
This study collects samples (like fluid from the lungs) during a planned bronchoscopy to look for new ways to understand and predict children's breathing problems. It might help if your child already needs this procedure for a medical reason.
WarsawAges Up to 17 years - NCT06760039RecruitingPhase 1/Phase 2
Comparing R-CMOP and R-CHOP for first-time DLBCL treatment
This trial tests if a new drug combination (R-CMOP) works as well as or better than the usual combination (R-CHOP) for people with a type of lymphoma called DLBCL who haven't had treatment yet.
Fuzhou, FujianAges 18–80 - NCT06904599RecruitingPhase 2
Testing hCG for acute GVHD after a stem cell transplant
This study tests if a hormone called hCG can help treat moderate-to-severe graft-versus-host disease (GVHD) after a stem cell transplant. It is for adults who have recently developed GVHD and need steroids, but have not been on high-dose steroids for long.
Monterrey, Nuevo LeónAges 18 years+ - NCT03945968Recruiting
Risk scores after abdominal surgery for people with health conditions
This study looks at how other health problems affect the chance of postoperative complications after abdominal surgery. It aims to help doctors better predict risk and decide on the safest care for you.
ArkhangelskAges 18 years+ - NCT06909474RecruitingPhase 1
CD5-targeted CAR-NK therapy for relapsed T-cell blood cancers
This trial tests a new therapy using your own immune cells (NK cells) engineered to find and kill cancer cells that carry the CD5 protein. It is for people with T-cell acute lymphoblastic leukemia or certain T-cell lymphomas that have not responded to treatment or have returned.
Wuhan, HubeiAges 18–75
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.