Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT06919393Recruiting
A study for adults with triple negative B-cell ALL
This study is for adults with B-cell acute lymphoblastic leukemia (ALL) that does not have three specific gene changes (called BCR-ABL1, TCF3-PBX1, and MLL-AF4). The study will look at people who are newly diagnosed or who have had their cancer come back.
Meldola, FCAges 18 years+ - NCT06918912RecruitingPhase 2
Loncastuximab tesirine for lymphoma after CAR-T therapy
This trial tests a drug called loncastuximab tesirine for people with diffuse large B-cell lymphoma or high-grade B-cell lymphoma that has come back or not responded after CAR-T cell therapy. It aims to see if the drug can help when other treatments have stopped working.
Alessandria, ALESSANDRIAAges 18–99 - NCT06919029Recruiting
New insulin pump study for children with new type 1 diabetes
This study tests a new insulin pump system (MiniMed 780G) in children aged 7-17 who were recently diagnosed with type 1 diabetes. It aims to see if this pump helps control blood sugar better and improves quality of life compared to standard insulin shots or older pumps.
AthensAges 7–17 - NCT06919341Recruiting
Spanish immune thrombocytopenia registry
This study collects data from people with immune thrombocytopenia (a condition where the immune system destroys platelets, causing low blood counts). It aims to better understand and track the disease over time.
A Coruña, A CoruñaAges 2 months+ - NCT05566769Recruiting
Test a phone tool for self-checks in NMOSD
This study tests a digital (phone) tool that helps people with NMOSD do unsupervised self-assessments between clinic visits. It looks at how well the tool works and whether it is safe and understandable for patients.
Los Angeles, CaliforniaAges 18 years+ - NCT03936153RecruitingPhase 2
Oral abexinostat for relapsed lymphoma after two prior treatments
This Phase 2 study tests how well and how safely an oral medicine called abexinostat works for people with diffuse large B-cell lymphoma that has come back or did not respond to the last treatment. It may help by shrinking lymphoma and controlling the disease using a medication taken by mouth.
BeijingAges 18 years+ - NCT04300101Recruiting
Study of a blood- and tissue-based index in large B-cell lymphoma
This study looks at a “Mixed Molecular Clinical Index” (MMCI), which combines test results from lymphoma tissue and clinical information. It aims to help better understand how diffuse large B-cell lymphoma behaves and how patients may respond to standard first-line treatment.
Meldola, FCAges 18 years+ - NCT06064695Recruiting
Electrical muscle stimulation exercise for myasthenia gravis
This study tests if whole-body electrical muscle stimulation exercise can help adults with generalized myasthenia gravis. It also enrolls healthy controls for comparison. If you have MG and can stand for about 15 minutes, this may be an option.
Fairway, KansasAges 18 years+ - NCT05945524Recruiting
Study of how teclistamab works in multiple myeloma patients
This study looks closely at patients’ immune cells to understand why teclistamab helps in multiple myeloma. Your participation could help doctors better predict who benefits and how the treatment works.
Amiens, FranceAges 18 years+ - NCT06696027Recruiting
Loss of Y chromosome in autoimmune and lung disease
This study looks at how the loss of the Y chromosome in blood cells may be linked to autoimmune and lung diseases in older men. By joining, you help researchers understand this connection better.
Bonn, North Rhine-WestphaliaAges 50 years+ - NCT06294652Recruiting
Austrian Lymphoma Patient Registry Study
This registry collects information from adults with lymphoma to better understand the disease and improve future treatments. It is open to all patients 18 or older with lymphoma.
Salzburg, State of SalzburgAges 18 years+ - NCT06537726Recruiting
Breath test for fungal infections in leukemia patients
This trial tests if a simple breath analysis can detect invasive fungal infections early in people with acute leukemia who are undergoing chemotherapy and have a low white blood cell count. Early detection could help start treatment sooner.
Zurich, Canton of ZurichAges 18 years+ - NCT06460142Recruiting
Biomarker study for giant cell arteritis and polymyalgia rheumatica
This study is looking for biomarkers (biological clues) in people with newly diagnosed or flaring giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). Participating may help researchers find better ways to diagnose and monitor these conditions.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06755281Recruiting
Testing to safely remove penicillin allergy labels
This study tests if people with a low-risk penicillin allergy can safely have the allergy label removed through a simple risk assessment and testing, without needing a full drug challenge. It aims to help more people get the right antibiotics when needed.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT02964858Recruiting
Testing the best radiation dose after R-CHOP for lymphoma
This trial studies how to choose the safest and most effective radiation dose for diffuse large B-cell lymphoma (a type of non-Hodgkin lymphoma) after standard chemotherapy. It may help improve disease control while aiming to limit side effects from radiation.
Mumbai, MaharashtraAges 18–65 - NCT05365672RecruitingPhase 2
Donor immune cell therapy during live kidney transplant
This Phase 2 trial studies a treatment using immune cells made from your living donor, given around the time of kidney transplant. It aims to improve transplant safety and outcomes by adjusting the immune response to the new kidney.
BerlinAges 18–69 - NCT05564936Recruiting
Digital tests for generalized myasthenia gravis using a smartphone
This study tests a smartphone-based digital tool that helps check symptoms in people with generalized myasthenia gravis (MG). It may help patients and clinicians track how the disease is doing over time using simpler, repeated assessments.
Aurora, ColoradoAges 18 years+ - NCT06685042RecruitingPhase 1/Phase 2
CAR T-cell therapy for severe autoimmune diseases
This study tests a new treatment called CAR T-cell therapy for people with severe autoimmune diseases that haven't gotten better with standard treatments. The goal is to see if it can help control the disease by reprogramming your immune cells.
Rome, LazioAges 18–65 - NCT06676657Recruiting
Closed loop with context-aware insulin delivery for type 1 diabetes
This study tests a smart insulin pump system that adjusts automatically during exercise. It aims to make managing blood sugar easier and safer.
Portland, OregonAges 18–100 - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+ - NCT06924762RecruitingPhase 2/Phase 3
Low-dose IL-2 for chronic hives that don't respond to usual treatment
This study tests a low-dose immune therapy (interleukin-2) for people with chronic hives that don't get better with standard allergy pills. If you are an adult with ongoing hives and itching despite daily antihistamines, this trial might offer a new treatment option.
Changsha, HunanAges 18–74 - NCT05028153RecruitingPhase 2
Azithromycin for young children with asthma-like hospital symptoms
This trial tests whether the antibiotic azithromycin can help children in the hospital who are having asthma-like breathing symptoms. If you qualify, your child may get azithromycin as part of the study and will be monitored closely for side effects and breathing improvement.
Gentofte MunicipalityAges 1 year–5.9 years - NCT02433028Recruiting
Long-term study for MS and related nervous system conditions
This is a long-term hospital study that follows people diagnosed with MS (and a few related conditions) to understand how disease changes over time. You may be asked to have regular check-ups, brain scans, and provide blood samples so researchers can track disease and treatment effects.
Aarau, Canton of AargauAges Any age - NCT06286644Recruiting
Hops compounds and your immune system
This study looks at how compounds found in hops (used in beer) affect your immune system. If you are a healthy adult, you may join and help researchers learn more about how these natural substances work.
ViennaAges 18–70
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.