Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07203781Recruiting
Breathing machine settings and their effect on breathing effort
This study is testing how different settings on a breathing machine affect your breathing effort and drive. It may help doctors find the best ventilator settings for patients with severe low oxygen levels.
Nijmegen, GelderlandAges 18 years+ - NCT07203352RecruitingPhase 3
Targeted drugs plus chemo for T-cell acute lymphoblastic leukemia
This trial tests whether adding targeted drugs to standard chemotherapy works better for adults newly diagnosed with T-ALL. If you have not had any prior treatment for leukemia, this study might be an option.
Guangzhou, GuangdongAges 18–70 - NCT07206407Recruiting
Study on how a test product affects your immune system
This trial tests whether a natural product can quickly change your immune system. It is looking for healthy adults who can keep a steady diet and lifestyle for the study period.
Klamath Falls, OregonAges 18–75 - NCT07209930Recruiting
Exercise and glucose response in type 1 diabetes
This trial looks at how blood sugar levels change during exercise in healthy adults and people with type 1 diabetes. It may help understand how the body responds to exercise differently from person to person.
Dublin, DublinAges 18–60 - NCT07207148Recruiting
Ocrelizumab and weight-loss drugs for MS
This study looks at combining ocrelizumab (an MS treatment) with GLP-1 agonists (like Ozempic, used for weight management) in people with MS. It aims to see if the combination is safe and beneficial.
Chicago, IllinoisAges 18–70 - NCT07206277Recruiting
Using Fibroscan to guide lower anti-rejection medicine after liver transplant
This trial uses a special ultrasound (Fibroscan) to check your liver health and see if you can safely reduce your anti-rejection medications. It is for people who are at least 2 years past a liver transplant and whose liver is working well.
Edmonton, AlbertaAges 18 years+ - NCT07209059RecruitingPhase 2
Nivolumab plus first-line therapy for advanced Hodgkin lymphoma
This trial tests whether adding the immunotherapy drug nivolumab to the first treatment of advanced Hodgkin lymphoma can improve outcomes. It uses PET scans to guide therapy, potentially reducing the need for stronger chemotherapy.
MoscowAges 18–60 - NCT04494503RecruitingPhase 1/Phase 2
Study drug for hard-to-treat CLL or SLL after relapse
This Phase 1/2 study tests APG2575 alone or combined with other treatment in people whose CLL/SLL has come back or did not respond to prior therapy. The goal is to see how well the treatment works and how safe it is.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05635162RecruitingPhase 2
Zanubrutinib plus rituximab for slow-growing mantle cell lymphoma
This trial studies whether combining zanubrutinib and rituximab can better control indolent (slow-growing) mantle cell lymphoma. It aims to improve how long participants can stay without the lymphoma worsening.
DerbyAges 18 years+ - NCT06138431Recruiting
Group therapy for parents of children with food allergies
This study tests a group therapy program to help parents manage anxiety or depression related to their child's serious food allergy. You'll attend 6 weekly group sessions and fill out questionnaires online to see if the program helps you feel better.
Kansas City, MissouriAges 1.5 years–17 years - NCT06927375RecruitingPhase 4
Combination drug therapy for thyroid eye disease
This study tests a combination of two drugs, tocilizumab and flupentixol-melitracen, in people with active, moderate-to-severe thyroid-associated eye disease (TED). It aims to see if this combination can reduce eye bulging, double vision, and anxiety symptoms.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06930950Recruiting
Cashew allergy treatment study for children
This study tests if giving small, increasing amounts of cashew can help children outgrow their allergy. It may be an option for kids who are allergic to cashew and have had a clear allergic reaction in a food challenge.
HelsinkiAges 1–17 - NCT05905640Recruiting
PrEP clinic support study for Kenya health workers and policy makers
This trial tests a “one-stop” support pathway meant to make it easier for PrEP clinics in Kenya to deliver PrEP care. It involves interviews with people using PrEP services and with healthcare and policy leaders who help run or guide PrEP delivery.
KisumuAges 15 years+ - NCT06355583RecruitingPhase 2
Gut bacteria transplant before stem cell transplant
This trial tests whether giving a transplant of healthy gut bacteria (fecal microbiota transplant) before a stem cell transplant can improve outcomes for people with certain blood cancers or bone marrow disorders.
Birmingham, EnglandAges 18 years+ - NCT06657703RecruitingPhase 1
Safety of a single dose of HC022 in healthy adults
This trial tests a single dose of an investigational drug called HC022 in healthy volunteers to see how safe it is and how the body handles it. If you are a healthy adult, you may be able to join and help researchers learn the first steps about this new medicine.
BeijingAges 18–55 - NCT06780709Recruiting
Wellness program for neuromyelitis optica patients
This trial tests a structured wellness program to improve quality of life for people with neuromyelitis optica (NMOSD). It is designed to be accessible for any level of disability.
New York, New YorkAges 18 years+ - NCT06837922RecruitingPhase 3
Study of MG-K10 for moderate to severe asthma
This trial tests a new drug called MG-K10 for people with moderate to severe asthma that is not well controlled with current treatments. It aims to see if the drug can reduce asthma attacks and improve breathing. You may be able to join if you have had asthma for at least a year, use high-dose inhalers plus another controller medicine, and have had a recent flare-up.
Guangzhou, GuangdongAges 12–75 - NCT06916819Recruiting
Food allergy testing: at home or in clinic?
This study compares doing a food challenge at home versus in a medical clinic for people who think they might be allergic to a food. If you are over 18 and your skin test to that food is negative, you may be able to join.
Melbourne, VictoriaAges 18 years+ - NCT06931275Recruiting
Reducing technology gaps in type 1 diabetes care
This trial tests if sending reminders to doctors can help more Black and Hispanic people with type 1 diabetes get access to helpful diabetes technology. It aims to reduce unfair differences in who gets to use these tools.
Boston, MassachusettsAges 2–95 - NCT05266898RecruitingPhase 4
HPV vaccine response study for people living with HIV
This trial studies how well the Gardasil-9 HPV vaccine triggers the body’s immune response in people living with HIV. It may help doctors understand the best way to protect against HPV-related cancers and infections in this population.
New Orleans, LouisianaAges 18–65 - NCT06846385RecruitingPhase 2/Phase 3
Testing a new shot for severe seasonal hay fever
This study tests a new injection called MG-K10 for people with moderate-to-severe seasonal hay fever that isn't well controlled by standard treatments like nasal sprays or antihistamines. The goal is to see if it can reduce your allergy symptoms over the pollen season.
Beijing, Beijing MunicipalityAges 18–75 - NCT05956457Recruiting
Using wearable and PRO check-ins for relapsed myeloma
This study uses your self-reported symptoms (PRO) and wearable/device data to help improve care for people with relapsed multiple myeloma who are starting new treatment. It may help by providing insights about how you’re doing during therapy—without changing your cancer treatment in a study-specific way.
Seattle, WashingtonAges 18 years+ - NCT06873308Recruiting
Infection activity in travelers and migrants with chronic schistosomiasis
This trial looks at how active a long-term schistosomiasis infection is in travelers and migrants. It aims to better understand the infection to help guide treatment.
AntwerpAges 5 years+ - NCT06875167Recruiting
Automated insulin therapy for kids 2-6 with type 1 diabetes
This study tests a semi-automated insulin pump system in very young children (ages 2–6) with type 1 diabetes. It aims to see if the device improves quality of life and blood sugar control.
Nice, FranceAges 2–6
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.