Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06180174RecruitingPhase 1
CD19-targeted CAR-T cells for relapsed B-cell lymphoma
This trial tests a new type of immune cell therapy (CAR-T cells) that targets a protein called CD19 on your lymphoma cells. It's for people whose B-cell lymphoma has returned or not responded to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06181656Recruiting
Pneumonia Vaccine Study for Esophageal and Liver Cancer Patients
This trial studies how well the pneumonia vaccine works in people with esophageal or liver cancer who have low white blood cell counts after chemoradiation. It aims to see if the vaccine can still protect them from infection.
Houston, TexasAges 18 years+ - NCT06182436Recruiting
Virtual reality for pain during eczema injection
This trial tests whether playing a virtual reality game during a dupilumab injection (for eczema) can help reduce pain and anxiety. It's for kids and teens aged 6 to 17 who are already taking or about to start this medicine.
Montreal, QuebecAges 6–17 - NCT06182774RecruitingPhase 3
Fixed vs ongoing treatment for older adults with new myeloma
This trial compares stopping treatment after a set number of cycles versus continuing it for people over 65 or those who cannot have a stem cell transplant. It tests whether a fixed treatment period works as well as long-term treatment for newly diagnosed multiple myeloma.
Edmonton, AlbertaAges 18 years+ - NCT06183398Recruiting
Plant allergy test study using skin prick tests
This study is checking how common allergies to certain plants are by using skin prick tests. If you or your child are already coming to the allergy clinic, you might be able to take part.
MontpellierAges 5 years+ - NCT06183645Recruiting
Predicting CIDP decline during IVIg treatment changes
This study looks at people with CIDP who are stable on IVIg treatment to see if we can predict when they might get worse if their treatment is adjusted. It aims to make treatment management easier and more personalized.
Liège, LiègeAges 18–99 - NCT06184100Recruiting
Online Self-Management Program for Teens with JIA
This study tests an online self-management program for teens with newly diagnosed JIA. It helps you learn skills to manage your condition, connect with others, and feel more in control.
Calgary, AlbertaAges 12–17 - NCT06185751RecruitingPhase 1
Testing CS1 CAR-T for multiple myeloma
This study tests a new cell therapy called CS1 CAR-T, which helps your immune system attack myeloma cells that still grow after several other treatments. It's for people who have already tried at least three different types of therapy.
St Louis, MissouriAges 18 years+ - NCT06186856Recruiting
Mast cell disease study in France
This study collects health information from people living in France who have a mast cell disease (like mastocytosis or mast cell activation syndrome). It aims to better understand these conditions by tracking who is affected and how they are doing.
AmiensAges Any age - NCT06187441RecruitingPhase 3
Testing a treatment break in multiple myeloma
This trial is for people with multiple myeloma who have already completed 12 cycles of a standard treatment (daratumumab, lenalidomide, and dexamethasone) and are doing well. It tests whether taking a break from treatment is safe and effective, instead of continuing without a break.
's-HertogenboschAges 18 years+ - NCT06189157RecruitingPhase 1/Phase 2
Testing MB-CART19.1 therapy for severe lupus
This trial tests a new type of treatment called CAR T-cell therapy (MB-CART19.1) for people with severe lupus that has not responded to other treatments. It aims to see if this therapy can help control lupus and improve organ function.
ErlangenAges 18 years+ - NCT06189391RecruitingPhase 1
Testing CN201 for people with relapsed or refractory B-cell lymphoma
This study tests a new drug called CN201 (also known as MK-1045) for people with certain types of B-cell lymphoma that have come back or not responded to previous treatments. The goal is to see if the drug can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18–75 - NCT06191887RecruitingPhase 1
BAFFR-targeting CAR-T cells for relapsed B-cell blood cancers
This trial tests a new type of immune cell therapy (CAR-T cells) that targets a protein called BAFFR on B-cell blood cancers. The goal is to see if it can shrink tumors when given after a short chemotherapy course to prepare the body.
Jacksonville, FloridaAges 18 years+ - NCT06192914Recruiting
EPAP: A follow-up survey for severe food allergies
This study is a follow-up survey for people who have had a severe allergic reaction (anaphylaxis) to certain foods and are already in a larger allergy registry. By answering questions online, you can help researchers understand more about living with food allergies.
Berlin, State of BerlinAges Any age - NCT06193369Recruiting
Digital peer support for young adults with cancer
This trial connects you with a trained peer (someone who has been through cancer) who provides support and guidance online. It's for young adults who finished treatment for certain cancers in the past year.
Toronto, OntarioAges 18–40 - NCT06195800Recruiting
Biomarkers after stem cell transplant for neurological diseases
This trial looks at biomarkers (biological signs in your blood) in people with immune-mediated neurological diseases. It compares those getting a stem cell transplant to those on high-efficacy MS treatments to understand how these therapies work.
Sheffield, EnglandAges 16 years+ - NCT06195891RecruitingPhase 1
Orca-T stem cell transplant for older adults with blood cancer
This study tests a new way to give donor stem cells (called Orca-T) after a special type of chemotherapy and radiation. It is for people aged 60–75 with certain blood cancers that have not responded well to standard treatments.
Duarte, CaliforniaAges 60 years+ - NCT06196255RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant or relapsed multiple myeloma
This trial tests a new CAR-T cell therapy that targets FcRL5 on myeloma cells. It's for people whose myeloma has come back or stopped responding to other treatments, including stem cell transplant.
Xuzhou, JiangsuAges 18–70 - NCT06196034Recruiting
Genetic study of asthma severity and types
This study looks at how genes are linked to different types and severities of asthma. It aims to understand why asthma affects people differently, which could lead to better treatments.
Hong Kong, New TerritoriesAges 18–100 - NCT06198725Recruiting
Gut bacteria treatment for children with new type 1 diabetes
This study tests whether a special treatment aimed at gut bacteria can help children newly diagnosed with type 1 diabetes. It is for kids ages 6 to 12 who were diagnosed in the last 6 months and do not have other serious health conditions.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT06202898Recruiting
Study helping transgender women access HIV prevention (PrEP)
This study helps transgender women who are not regularly using PrEP (a daily pill to prevent HIV) get access to HIV prevention services. It uses a smartphone to take pictures and connect with support.
Orlando, FloridaAges 18 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT06203652Recruiting
Study of lymphoma causes and outlook
This study looks at why lymphoma happens and what factors affect how well people do. It collects information from patients diagnosed between 2007 and 2027 to better understand the disease.
Shanghai, Shanghai MunicipalityAges Any age - NCT06203951Recruiting
Better STI testing during pregnancy in Kenya
This study tests a simpler way to check for sexually transmitted infections (STIs) and HIV/syphilis during pregnancy in Kenyan clinics, to help keep both you and your baby healthy.
Homa BayAges Any age
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.