Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT06775860RecruitingPhase 3
Testing ICP-332 for moderate to severe eczema
This trial tests an oral medication called ICP-332 for adults with moderate to severe eczema (atopic dermatitis) who haven't gotten enough relief from topical creams. It aims to see if the drug can reduce skin inflammation and itching.
Hefei, AnhuiAges 18–75 - NCT06775912RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It's designed for people with certain autoimmune diseases like lupus, scleroderma, vasculitis, myositis, or Sjögren's syndrome that are not controlled by standard treatments.
Lianyungang, JiangusAges 18–70 - NCT06776510RecruitingPhase 1/Phase 2
NAD for immune thrombocytopenia study
This trial tests if a substance called NAD can help adults with immune thrombocytopenia (ITP) whose platelet levels stay low even after standard treatments. ITP is a condition where the immune system attacks platelets, causing easy bruising and bleeding. The study aims to see if NAD can safely raise platelet counts.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06776965Recruiting
Ultra-processed foods and rheumatic disease study
This study explores how eating ultra-processed foods affects people with chronic rheumatic diseases like rheumatoid arthritis, spondyloarthritis, or osteoarthritis. It aims to understand if diet plays a role in symptom management.
LyonAges 18 years+ - NCT06776952RecruitingPhase 3
Study of XNW5004 for relapsed or refractory peripheral T-cell lymphoma
This study tests a new oral tablet called XNW5004 for people with peripheral T-cell lymphoma (a type of blood cancer) that has come back or not responded to prior treatments. The goal is to see if this drug can help shrink tumors or slow the disease.
Beijing, Beijing MunicipalityAges 3 weeks–2 months - NCT06777134Recruiting
Pelvic floor issues and leg strength in MS patients
This study looks at how pelvic floor problems relate to leg strength and function in people with multiple sclerosis. It may help understand how to better treat these issues.
Istanbul, IstanbulAges 18–65 - NCT06777979RecruitingPhase 1
CAR T cell therapy for children with hard-to-treat leukemia
This trial tests a special kind of immune cell therapy that targets two markers (CD19 and CD22) on leukemia cells. It is for children and teens whose leukemia has come back multiple times or has not responded to standard treatment.
Memphis, TennesseeAges Up to 21 years - NCT06778343Recruiting
Biomarkers study for inflammatory rheumatic diseases
This study is looking for people with ankylosing spondylitis, rheumatoid arthritis, or lupus to help find biomarkers that may make diagnosis easier. If you have one of these conditions and haven't tried biologic therapies, you may be able to join.
LisbonAges 18–65 - NCT06778746Recruiting
Study of Biologics for Severe Asthma in Hong Kong
This study looks at how biologic medicines (special injections or infusions) are used to treat severe asthma in Hong Kong. It may help researchers understand why some people stop or switch these treatments.
Hong KongAges 18 years+ - NCT06779123Recruiting
Vagus nerve stimulation for rheumatoid arthritis
This trial tests a non-invasive device that stimulates a nerve in your ear to see if it can reduce rheumatoid arthritis symptoms. It is for people whose RA has not responded well to at least one biologic or targeted DMARD.
Lund, Skåne CountyAges 18 years+ - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT06780709Recruiting
Wellness program for neuromyelitis optica patients
This trial tests a structured wellness program to improve quality of life for people with neuromyelitis optica (NMOSD). It is designed to be accessible for any level of disability.
New York, New YorkAges 18 years+ - NCT06781359Recruiting
Study on plasmablastic lymphoma patients
This study looks back at medical records and tissue samples from people diagnosed with plasmablastic lymphoma (PBL) between 2000 and 2022. It aims to learn more about the disease and may help improve future care.
Aviano, PNAges 15 years+ - NCT06781437Recruiting
Lymphoma medical record review study
This study looks back at the medical records of people with lymphoma to learn more about the disease. It does not involve any new treatments or tests—just reviewing what happened in the past.
Bologna, BolognaAges 18 years+ - NCT06781515Recruiting
Hairy cell leukemia disease burden study
This study watches the course of hairy cell leukemia (HCL) in different phases—when first diagnosed, after it comes back, or long after successful treatment. The goal is to better understand the disease and plan future care.
Bologna, BolognaAges 18 years+ - NCT06781970Recruiting
Vitamin C for eye cell protection during cataract surgery
This trial tests whether taking vitamin C before and after cataract surgery can help protect the inner layer of the eye. It is for people aged 60 or older with hard, age-related cataracts who are having phacoemulsification surgery.
Jakarta, DKI JakartaAges 60 years+ - NCT06782217Recruiting
Safety study of bee and wasp venom allergy shots
This study monitors the safety of venom immunotherapy (allergy shots) for people with bee or wasp sting allergies. If you are starting this treatment, researchers will track how well you tolerate it over time.
Ferrol, A CoruñaAges 14 years+ - NCT06782464Recruiting
Freezing nerves for shoulder pain after stroke or brain injury
This trial tests if freezing certain nerves in the upper arm (cryoneurolysis) works as well as standard care for reducing shoulder pain and muscle tightness after a stroke or brain injury. It aims to improve function and ease caregiving tasks.
LuxembourgAges 18 years+ - NCT06782568Recruiting
Using ultrasound to prevent insulin lumps in diabetes
This study tests whether using ultrasound scans in diabetes clinics can help people avoid insulin-induced lipohypertrophy (lumps under the skin from injections). It is for people with diabetes who use insulin injections or a pump and have unstable glucose levels despite using a continuous glucose monitor.
LondonAges 18 years+ - NCT06782724RecruitingPhase 2
Psilocybin therapy for distress in advanced illness
This trial tests whether a single dose of psilocybin (a psychedelic medicine) can help reduce depression and distress in people with advanced lung disease, ALS, multiple sclerosis, or Parkinson's. You would receive preparation, the drug, and follow-up support in a safe, supervised setting.
PragueAges 18 years+ - NCT06782789Recruiting
Study of Tafasitamab and Lenalidomide for aggressive B-cell lymphoma
This study looks back at medical records of people with relapsed or refractory diffuse large B-cell lymphoma who received a combination of two drugs (tafasitamab and lenalidomide) through a special access program. The goal is to learn how well the treatment worked and what side effects occurred.
Bologna, BolognaAges 18 years+ - NCT06783101Recruiting
Smart Inhaler for Teens with Intellectual Disabilities and Asthma
This study tests a 'smart' inhaler that tracks when and how your child uses their asthma medicine. The goal is to help teens with intellectual or developmental disabilities manage asthma better at home.
Los Angeles, CaliforniaAges 10–17 - NCT06783816Recruiting
New immune cell therapy for blood cancers
This study tests a new type of CAR-T cell therapy designed to treat certain blood cancers (like leukemia, lymphoma, or multiple myeloma) that have come back or not responded to standard treatment. The cells are enhanced with IL-15 to help them work better.
Taiyuan, ShanxiAges Any age - NCT06784154Recruiting
HIV and heart attack risk: a study on hidden body fat
This study looks at how hidden fat deep inside the body (ectopic fat) might increase heart attack risk in people living with HIV. By joining, you will help researchers understand this link and find better ways to protect your heart.
LiverpoolAges 40 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.