Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,067 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,060
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 399
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Type 1 Diabetes132
- Rheumatoid Arthritis131
- Atopic Dermatitis122
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections105
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California498
- Maryland198
- Alabama178
- Florida151
- Arizona150
- Massachusetts118
- New York114
- Texas112
- Illinois84
- Colorado81
Recruiting studies6,067 total
- NCT06169150Recruiting
Studying nervous system issues in immune disorders
This study looks for and tracks nervous system problems in people with immune system disorders. It aims to better understand how infections or inflammation affect the brain and nerves in these patients.
Bethesda, MarylandAges 2–120 - NCT06173518RecruitingPhase 1
CAR T-cell therapy for children with B-cell leukemia or lymphoma
This trial tests a CAR T-cell therapy that targets CD19 on cancer cells. It is for children whose B-cell acute lymphoblastic leukemia or aggressive B-cell non-Hodgkin lymphoma has come back or not responded to other treatments.
Los Angeles, CaliforniaAges birth–18 years - NCT06158490Enrolling by invitationPhase 2
JYP0061 tablet for moderate to severe eczema
This trial tests a new tablet called JYP0061 for people with moderate to severe atopic dermatitis (eczema) that has lasted at least a year. It aims to see if the drug is safe and effective in reducing symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06163807Recruiting
Asthma and nasal polyps long-term observation study
This study follows people with asthma (with or without nasal polyps) to learn more about how the disease changes over time. If you already take part in the MEGA cohort or use a biologic drug for severe asthma, this may be a way to contribute to research while continuing your normal care.
Santiago de Compostela, AcoruñaAges 18–80 - NCT06167642Enrolling by invitation
Retinal health and nerve markers in MS patients taking ofatumumab
This study looks at how ofatumumab (Kesimpta) affects the back of the eye (retina) and certain nerve proteins in the blood in people with relapsing multiple sclerosis. It may help doctors understand how well the medication is protecting the eyes and nerves.
Baltimore, MarylandAges 18–70 - NCT06164483Recruiting
Hearing tests in people with MS or Parkinson's
This study checks how well people with multiple sclerosis (MS) or Parkinson's disease hear. It uses simple hearing tests to see if these conditions affect hearing.
Catania, SicilyAges 20–40 - NCT06168851RecruitingPhase 2
Anti-CD38 antibody for children with chronic ITP
This trial tests a new drug called anti-CD38 antibody for children and teens with chronic immune thrombocytopenia (ITP) whose platelet counts remain low despite other treatments. It may help increase platelet counts and reduce bleeding risk.
Tianjin, Tianjin MunicipalityAges 6–17 - NCT06156046Recruiting
Understanding bee venom tolerance in beekeepers
This study looks at how beekeepers develop tolerance to bee venom over time, comparing people who are new to beekeeping, experienced beekeepers without allergies, and beekeepers who have had a recent allergic reaction. If you fall into one of these groups, you may be able to join and help researchers understand how the immune system adapts to bee stings.
Plymouth, DevonAges 18 years+ - NCT06163508Enrolling by invitation
Long-term follow-up for Q-Cells recipients
This study is for people who have already received Q-Cells treatment. It does not test new treatments; instead, it checks on your health over a long time to see how you are doing.
Dallas, TexasAges Any age - NCT06169488Recruiting
Comparing fusion surgery to rehab for chronic low back pain
This trial compares two approaches for chronic low back pain caused by worn discs: lumbar fusion surgery versus a structured multidisciplinary rehabilitation program. It aims to see which treatment provides better long-term relief and function.
DrammenAges 20–65 - NCT06160310Recruiting
TSC & LAM Pregnancy Registry Study
This study is a registry that gathers information from pregnant women with Tuberous Sclerosis Complex (TSC) or Lymphangioleiomyomatosis (LAM), as well as infants born to them. The goal is to better understand how these conditions affect pregnancy and the baby's health.
Cincinnati, OhioAges Any age - NCT06176690RecruitingPhase 1
Donor cell therapy for CD30-positive lymphomas
This trial tests a new type of immune cell therapy for CD30-positive lymphomas. The cells are made from donated blood and are designed to find and attack your cancer.
Houston, TexasAges 12–75 - NCT06178744Recruiting
AI in heart transplant ultrasound study
This study uses artificial intelligence to look at echocardiograms (ultrasounds of the heart) from heart transplant patients. It aims to see if AI can help predict rejection or other problems, potentially reducing the need for biopsies.
Rochester, MinnesotaAges 18 years+ - NCT06172166Recruiting
A team approach for young adults with type 1 diabetes
This study tests a transdisciplinary care model for young adults with type 1 diabetes as they move from pediatric to adult healthcare. The goal is to provide coordinated support during this important transition period.
Wilmington, DelawareAges 17 years+ - NCT06181656Recruiting
Pneumonia Vaccine Study for Esophageal and Liver Cancer Patients
This trial studies how well the pneumonia vaccine works in people with esophageal or liver cancer who have low white blood cell counts after chemoradiation. It aims to see if the vaccine can still protect them from infection.
Houston, TexasAges 18 years+ - NCT06161376Recruiting
Urine test for bladder problems in multiple sclerosis
This study looks at a substance in urine (called S1P) to see if it can help doctors find bladder overactivity in people with multiple sclerosis. If successful, this test could simplify diagnosis and avoid more invasive procedures.
ToulouseAges 18–75 - NCT06170970RecruitingPhase 2
Solriamfetol for fatigue in multiple sclerosis
This study tests whether solriamfetol, a medication that promotes wakefulness, can reduce fatigue in people with multiple sclerosis. If you struggle with tiredness and sleepiness, this trial may help you understand how this drug works for MS-related fatigue.
Baltimore, MarylandAges 18–60 - NCT06159127Recruiting
SMART@Home: A smartphone program for teens with chronic conditions
This trial is testing a new program called SMART@Home that helps teens manage their long-term health conditions using a smartphone app. It aims to see if this approach is practical and helpful for teens with conditions like asthma.
Cincinnati, OhioAges 12–18 - NCT05963971Recruiting
Bilingual online program to prevent weight gain in childhood leukemia
This trial tests a bilingual, online program to help children and teens who have ALL (a type of leukemia) stay at a healthy weight during the maintenance phase of treatment. It may help lower the chance of gaining too much weight while on chemotherapy.
New York, New YorkAges 5–21 - NCT06136091Recruiting
Asthma study in select communities using a smartphone app
This study looks at how asthma affects people in certain communities and tests a new way to manage it using a smartphone app. It is for people with long-standing asthma and those without asthma, to compare their health over time.
Aurora, ColoradoAges 6–17 - NCT06004986RecruitingPhase 4
Lowering Dupilumab Dose in Controlled Eczema
This study looks at whether people with well-controlled eczema can safely lower their dose of dupilumab (an injected medication). It aims to see if a reduced dose still keeps eczema under control.
Amsterdam, North HollandAges 18 years+ - NCT06134219Recruiting
Course for brain fatigue after Graves' disease
This study tests a course designed to help with brain fatigue (mental tiredness) that can happen after Graves' disease. It is for people whose thyroid levels are stable but who still struggle with fatigue.
GothenburgAges 18–72 - NCT06137144RecruitingPhase 1/Phase 2
AZD3470 for lymphoma that has come back or not responded
This study tests an experimental drug called AZD3470 for people with certain types of blood cancer (lymphoma) that have come back or not responded to standard treatments. The drug will be given alone or with other cancer medicines to see if it is safe and effective.
Duarte, CaliforniaAges 12 years+ - NCT06144554Recruiting
Omnipod 5 pump study for type 1 diabetes
This study follows people with type 1 diabetes who are using the Omnipod 5 insulin pump. The goal is to understand how well the system works in everyday life by collecting data from your pump, continuous glucose monitor, and occasional home blood tests over one year.
Buffalo, New YorkAges 2 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,067 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,241 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.