Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07031063RecruitingPhase 4
HIV treatment study for people starting therapy
This study compares two HIV medications (DTG/3TC and BIC/TAF/FTC) to see which works better and is safer for people who have never taken HIV treatment before. It may help you find a once-daily pill that controls the virus and has fewer side effects.
Mexico City, AzcapotzalcoAges 18 years+ - NCT07031102Recruiting
Methacholine challenge test for children with asthma
This study measures how children's airways respond to a substance called methacholine to understand how asthma affects lung function. It compares children with and without asthma to help improve diagnosis and treatment.
HelsinkiAges 7–15 - NCT07031713RecruitingPhase 1
Testing CT1192 cells for lupus that hasn't responded to treatment
This trial tests a new treatment called CT1192, which uses your own immune cells (T-cells) that are modified to target and calm overactive immune cells causing lupus. It is designed for people with moderate to severe lupus that hasn't improved with standard therapies like steroids, immunosuppressants, or biologics.
Wuhan, HubeiAges 18–60 - NCT07032103Recruiting
Lymphoma study tracking patient outcomes over time
This study follows people with Hodgkin or non-Hodgkin lymphoma who need strong treatment to try to cure their cancer. The goal is to learn more about how the disease and its treatment affect patients over time.
SeoulAges Any age - NCT07032129RecruitingPhase 1/Phase 2
Targeted cell therapy for multiple myeloma that returned or didn't respond
This trial tests a new type of treatment using your own immune cells (called CAR-T cells) that target two proteins on myeloma cells: BCMA and GPRC5D. It's for people whose myeloma has come back or stopped responding to standard treatments, and who may have few other options left.
Beijing, Beijing MunicipalityAges 21–90 - NCT07032363Recruiting
Depression and HIV treatment support study
This study tests a program that helps people with HIV manage depression and stick to their treatment. It's for adults in Cape Town, South Africa, who have a detectable HIV viral load or may have one, and who show signs of depression.
Miami, FloridaAges 18 years+ - NCT07032714RecruitingPhase 1
Mezigdomide and talquetamab for relapsed multiple myeloma
This trial tests a combination of two drugs, mezigdomide (a pill) and talquetamab (an injection), for people with multiple myeloma that has come back or not responded to at least three prior treatments. The goal is to see if this combination can help control the disease.
Boston, MassachusettsAges 18 years+ - NCT07033260Recruiting
Carotid ultrasound to predict low blood pressure during dialysis
This study looks at whether an ultrasound of the carotid artery (the main artery in your neck) can help predict drops in blood pressure during dialysis. It may help doctors find people at risk for low blood pressure during treatment.
Wuhu, Outside of the USAges 18–80 - NCT07033975Recruiting
Specialized diet for multiple sclerosis
This trial is testing a specialized diet for people with multiple sclerosis (MS) who are not too severely disabled. You may be able to join if you have mild to moderate MS and do not have a diagnosed digestive disorder.
Diepenbeek, LimburgAges 30–65 - NCT07034196Recruiting
Comparing RA care: primary care vs. rheumatologist
This study compares RA care from your primary care doctor (with extra training) to care from a rheumatologist. It's for people with stable RA living in northern New York who want to see if primary care can work as well as a specialist.
Potsdam, New YorkAges 18 years+ - NCT07037511Recruiting
Salbutamol in endurance athletes: a screening study
This trial tests how the asthma medication salbutamol affects endurance athletes. If you are a healthy athlete in running or cycling, your data may help improve sports safety.
Vancouver, British ColumbiaAges 18–55 - NCT07038382RecruitingPhase 2
Study of HLX79 with Rituximab for Active Kidney Disease
This trial tests a new drug called HLX79 (a human sialidase fusion protein) combined with rituximab, compared to a placebo, for people with active membranous nephropathy (a kidney disease). It aims to see if this combination can reduce protein in the urine and improve kidney function.
BeijingAges 18–75 - NCT07039617Recruiting
Testing a new insulin delivery algorithm at home for type 1 diabetes
This study compares a new automated insulin delivery algorithm (AIDANET) in two modes: fully closed-loop (no user input needed) versus hybrid closed-loop (user still gives some insulin for meals). It tests how well the algorithm works in real-life settings for adults with type 1 diabetes.
Charlottesville, VirginiaAges 18 years+ - NCT07040306Recruiting
Follow-up study on drug therapy for Graves' disease
This study looks at how well medication works for people with Graves' disease in China. It may help doctors understand the best treatment options for both new cases and relapses.
Shenyang, LiaoningAges 18 years+ - NCT07040332Recruiting
Understanding allergic bronchopulmonary aspergillosis
This study looks at why some people with asthma get a lung infection from mold called aspergillus. It will help doctors better understand the condition and how to treat it.
Jinan, ShandongAges 18 years+ - NCT07040774Recruiting
Study of type 1 interferonopathies in Europe
This study looks at people with a confirmed type 1 interferonopathy, a rare immune condition caused by a gene change. It aims to learn more about how the condition progresses over time.
InnsbruckAges Any age - NCT07040930RecruitingPhase 1
Testing the safety of GenSci120 in healthy adults
This study tests a new drug called GenSci120, given as multiple injections under the skin, to see if it is safe in healthy adults. It will also measure how the drug moves through the body and how it affects certain immune markers.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07041268RecruitingPhase 2
Rituximab for recent type 1 diabetes in teens
This trial tests if repeated infusions of rituximab (a drug that calms the immune system) can help preserve insulin production in adolescents newly diagnosed with type 1 diabetes. It is for teens in Russia who started diabetes treatment within the last 4 months.
MoscowAges 12–18 - NCT07041801RecruitingPhase 1/Phase 2
Stem cell therapy for lupus patients
This trial tests whether a type of stem cell from umbilical cords can help people with systemic lupus erythematosus (an autoimmune disease). It aims to find a new way to reduce lupus symptoms and improve quality of life.
Shenzhen, GuangdongAges 18–65 - NCT07042126RecruitingPhase 3
Testing 611 for Teen Eczema (moderate to severe)
This trial tests a new injectable medicine (611) for teenagers with moderate to severe eczema that hasn't been helped enough by creams. It aims to see if the drug can safely reduce itching and skin symptoms.
Beijing, Beijing MunicipalityAges 12–17 - NCT07042438RecruitingPhase 2
Fecal transplant to improve CAR T therapy for lymphoma
This study tests whether a fecal transplant (transferring healthy gut bacteria) can improve outcomes for people with certain lymphomas who have taken strong antibiotics and are about to get CAR T-cell therapy (Yescarta). The goal is to see if rebuilding gut bacteria helps the treatment work better.
Duarte, CaliforniaAges 18 years+ - NCT07043946RecruitingPhase 1/Phase 2
Budoprutug for immune thrombocytopenia
This trial tests a new drug called budoprutug for people with immune thrombocytopenia (ITP), a condition where your immune system attacks your own platelets, causing low counts. The study aims to see if the drug can safely raise platelet levels and reduce bleeding risk.
PlovdivAges 18 years+ - NCT07044297RecruitingPhase 3
A study of a new long-acting shot to prevent HIV
This study tests an investigational long-acting shot (MK-8527) to prevent HIV. It is for HIV-negative people who are at higher risk through anal sex without condoms, and who have not used other long-acting HIV prevention before.
Birmingham, AlabamaAges 16 years+ - NCT07044427Recruiting
Fall prevention exercise for multiple myeloma patients
This trial tests if a home exercise program can help prevent falls in people with multiple myeloma. It is for patients who are currently receiving or have recently received cancer therapy and want to exercise at least three times a week.
Heidelberg, Baden WürtembergAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.