Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT07079423RecruitingPhase 2
Teclistamab for new advanced AL amyloidosis
This trial tests a new drug called teclistamab for people newly diagnosed with advanced (stage IIIB) AL amyloidosis, a condition where abnormal proteins build up and damage organs. The goal is to see if teclistamab can help control the disease.
BeijingAges 18 years+ - NCT07083856Recruiting
Reiki and self-acupressure for people with MS
This study tests two relaxing therapies — Reiki (a gentle hands-on energy technique) and self-acupressure (applying mild finger pressure on specific points) — for people with multiple sclerosis. It looks at how these treatments affect symptoms like anxiety, depression, and fatigue.
Muğla, Fethi̇yeAges 18–75 - NCT07083882RecruitingPhase 2
Capsule transplant for newly diagnosed type 1 diabetes
This study tests if taking capsules with processed donor stool can help preserve insulin-making cells in people recently diagnosed with type 1 diabetes. The treatment aims to slow the loss of insulin production.
AmsterdamAges 18–45 - NCT07084480Recruiting
A study on giant cell arteritis for precision medicine
This trial looks at giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) to find more personalized treatments. If you have been diagnosed with either condition, you may be able to help researchers understand these diseases better.
WürzburgAges 18 years+ - NCT07084662RecruitingPhase 2/Phase 3
Xinlikang capsule for fatigue after lymphoma treatment
This trial tests a Chinese herbal capsule, Xinlikang, to see if it helps reduce fatigue and improve immune function after chemotherapy for diffuse large B-cell lymphoma. It is for people who have finished their first treatment and still feel very tired.
Guangzhou, GuangdongAges 18 years+ - NCT07085039RecruitingPhase 2
Ruxolitinib for previously treated idiopathic multicentric Castleman disease
This trial tests the drug ruxolitinib for people with idiopathic multicentric Castleman disease (iMCD) whose symptoms are not well controlled by standard anti-IL-6 therapy. Ruxolitinib is a pill taken by mouth that may help reduce inflammation and improve symptoms.
Philadelphia, PennsylvaniaAges 18–80 - NCT07085507RecruitingPhase 1/Phase 2
Testing a new drug for multiple sclerosis in healthy people and MS patients
This trial tests an experimental oral drug called VT7208 in both healthy volunteers and people with multiple sclerosis (MS). The goal is to see if it is safe and how the body processes it, which could lead to a new treatment option for MS.
Adelaide, South AustraliaAges 18–65 - NCT07085559RecruitingEarly Phase 1
Metabolically armed BCMA CAR-T for relapsed plasma cell cancer
This trial tests a new type of CAR-T cell therapy (Meta10-BCMA) that is "metabolically armed" to better fight cancer cells. It's for people with plasma cell cancers that have come back or not responded to multiple prior treatments, and whose cancer cells carry the BCMA protein.
Hefei, AnhuiAges 19–75 - NCT07085676RecruitingPhase 1
CAR-T cell therapy for autoimmune diseases that resist treatment
This study tests a new cell therapy called CAR-T (using your own immune cells) for people with severe autoimmune diseases like lupus, scleroderma, or myositis that have not improved with standard treatments. The goal is to see if it can safely reduce disease activity.
JerusalemAges 18–80 - NCT07085975RecruitingPhase 1
Safety of inhaled ATP cough challenges
This study tests how safe and repeatable an inhaled ATP cough challenge is. It first enrolls healthy adults, then people with chronic cough or mild asthma who have not used steroid inhalers recently.
Hamilton, OntarioAges 18 years+ - NCT07086976RecruitingPhase 3
Study of oral rilzabrutinib for warm autoimmune hemolytic anemia
This trial tests an oral medication (rilzabrutinib) against a placebo for people with warm autoimmune hemolytic anemia (wAIHA). It aims to see if the drug can help control the disease with fewer side effects than current treatments.
Phoenix, ArizonaAges 18 years+ - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT07087106RecruitingPhase 4
Glucose use in the brain of people with MS
This study uses a special PET scan to see how the brain uses sugar (glucose) in people with multiple sclerosis (MS) compared to healthy volunteers. It may help researchers understand energy changes in the brain related to MS.
Boston, MassachusettsAges 18–70 - NCT07087145Recruiting
HPV test by mail for men with HIV
This trial explores if mailing an HPV self-test kit to your home is a good way to screen for HPV. It's for men over 35 who have sex with men, including trans women, and are living with HIV.
San Francisco, CaliforniaAges 35 years+ - NCT07087912RecruitingPhase 4
Dengue vaccine safety in people with autoimmune rheumatic diseases
This study tests the safety and immune response of a dengue vaccine in people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are on low-dose or no immune-suppressing medications. It also includes healthy volunteers for comparison.
São Paulo, São PauloAges 12–59 - NCT07087873Recruiting
Testing brain stimulation for memory problems in inflammatory diseases
This trial tests if a gentle electrical current applied to the scalp can improve memory and thinking in people with certain inflammatory conditions that affect the brain and spinal cord.
Beijing, Beijing MunicipalityAges 18–60 - NCT07089381Recruiting
Resveratrol for rheumatoid arthritis
This study tests whether resveratrol (a natural substance found in grapes) can help control moderate-to-high rheumatoid arthritis when added to your current RA medications. It aims to see if it reduces disease activity safely.
CairoAges 18 years+ - NCT07089836Recruiting
Syphilis blood test study for at-risk and healthy people
This study tests two new blood tests for syphilis. It compares them to approved tests using blood from people who may have or had syphilis, including pregnant women, HIV-positive people, and healthy volunteers.
Lancaster, CaliforniaAges 13 years+ - NCT07089966Recruiting
PrEP delivery in family planning clinics
This trial tests a program where HIV testing counselors help family planning patients learn about and get PrEP, a daily pill that prevents HIV. It aims to make PrEP easier to access in clinics you may already visit.
KisumuAges 15 years+ - NCT07091318RecruitingEarly Phase 1
CBT for insomnia in type 1 diabetes
This study tests whether cognitive behavioral therapy for insomnia (CBTi) can improve sleep in people with type 1 diabetes. It may help those who have poor sleep quality and use a continuous glucose monitor.
Chicago, IllinoisAges 18–65 - NCT07093073RecruitingPhase 1
CAR-T therapy for B-cell lymphoma
This trial tests a new CAR-T cell therapy (called ssCART-19) for people with B-cell lymphoma that has not responded to standard treatments or has come back. The therapy uses your own immune cells to target and kill cancer cells.
ShanghaiAges 2–75 - NCT07093333RecruitingPhase 2
Testing a new antibody treatment for anti-NMDAR brain disease
This study tests a new medicine (ART5803) in people whose immune system attacks a brain receptor called NMDAR, causing encephalitis (brain swelling) or psychiatric symptoms. It aims to see if the medicine can reduce symptoms like confusion, memory problems, or psychosis.
SeoulAges 18–65 - NCT07093554RecruitingPhase 1
Talquetamab and Cilta-cel for relapsed multiple myeloma
This trial tests giving an immunotherapy drug (talquetamab) before CAR T-cell therapy (cilta-cel) to see if it helps people with multiple myeloma that has come back or stopped responding to other treatments.
Milwaukee, WisconsinAges 18 years+ - NCT07093606Recruiting
Eltrombopag and liver function in ITP patients
This study looks at how the drug eltrombopag affects the liver in people with primary ITP (immune thrombocytopenic purpura), a condition where the immune system destroys platelets. It aims to check if liver problems develop during treatment and who might be at higher risk.
SohagAges 18–75
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.