Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,147
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,230 total
- NCT02760238Recruiting
Myeloproliferative Neoplasms patient registry study
This is a research registry for people who have certain blood cancers called myeloproliferative neoplasms (MPNs). It helps researchers learn about the disease over time and may help future studies find and compare patients.
Toronto, OntarioAges Any age - NCT02869555Recruiting
Study of people with multiple myeloma in a patient database
This is a study that collects information from people diagnosed with multiple myeloma. It may help researchers understand the disease and improve future care by using past and ongoing patient data.
Marseille, Bouches-du RhôneAges 18–95 - NCT02241265Recruiting
Testing how lung breathing tests respond to bronchial treatment
This trial looks at how lung function test results change after bronchial thermoplasty in adults with severe asthma. It may help doctors understand who benefits from this procedure based on breathing test measures.
Oklahoma City, OklahomaAges 18–99 - NCT02432560Recruiting
Testing sirolimus for long-term treatment of LAM
This trial studies whether sirolimus can be used safely and works over time for LAM, a rare lung disease. You may be able to join if you already use (or cannot use) certain lung-targeting medicines called mTOR inhibitors, and if you can do regular clinic visits and breathing tests.
Stanford, CaliforniaAges 18 years+ - NCT02168868Recruiting
Blood tests to find autism-related protein signals
This study looks at blood samples from children (and sometimes parents) to see if certain protein patterns can help identify or better understand autism spectrum disorder. The results could support finding “biomarkers,” which are measurable signs that may guide future research or care.
JerusalemAges 10 months–19 years - NCT02169518Recruiting
Testing blood fat markers in diabetes and heart health
This study measures how certain blood “fat” markers relate to blood sugar control and inflammation. It may help researchers understand risk factors for heart disease in people with type 1 or type 2 diabetes, pre-diabetes, and people preparing for weight-loss surgery.
Manchester, LancashireAges 20–75 - NCT02192866Recruiting
Blood samples to study peanut and tree nut allergies
This study collects blood (or uses already-collected blood) to learn why peanut, tree nut, and related food allergies happen and how they behave during challenges. It may help researchers better understand allergies and improve future care.
Denver, ColoradoAges 1–75 - NCT02659956Recruiting
Study brain and eye changes on MRI in MS
This study looks at how multiple sclerosis (MS) affects MRI scans and other measurements in the brain, spinal cord, and eyes. It may help researchers better understand MS changes over time, using follow-up visits and, in the future, donated tissue after death.
Bethesda, MarylandAges 18–120 - NCT02649985RecruitingPhase 1/Phase 2
PET brain scan study for several brain and mood conditions
This early-phase study uses PET and MRI brain scans to better understand brain changes in multiple sclerosis, Alzheimer’s disease, and other neurological or mood conditions. The goal is to test whether these scans can show disease-related differences and guide future treatments.
Boston, MassachusettsAges 18–85 - NCT02592291Recruiting
Using a phone app to help manage long-term health needs
This study tests a mobile phone system that helps people with long-term, complex health conditions manage daily life and get support. If you can use a smartphone and pass the study checks, you may be able to try the self-management tools.
Pittsburgh, PennsylvaniaAges 12 years+ - NCT02390752RecruitingPhase 1
Early drug study for children and young adults with hard-to-treat cancers
This Phase 1 trial tests pexidartinib (TURALIO) to see how safe it is and how well it works against refractory (hard-to-treat) leukemias and solid tumors, including tumors seen with NF1 and MPNST. It mainly helps researchers learn the best way to dose the medication and gather early signals of benefit.
Bethesda, MarylandAges 3–35 - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+ - NCT02365246RecruitingPhase 2
Test IgE immune-filter treatment for severe eczema
This Phase 2 study tests a treatment called IgE-specific immunoadsorption, which works by filtering certain immune signals in the blood. It is meant for adults with severe, long-lasting eczema that has not responded well (or could not be tolerated) to standard treatments.
LeuvenAges 18–70 - NCT02863692Recruiting
Registry study for chronic lymphocytic leukemia patients
This study is a registry that collects information about people with certain types of leukemia. It may help researchers understand the disease course and how patients are treated, including people who are newly diagnosed, currently treated, referred for transplant, or have relapsed.
Dresden, SaxonyAges 18 years+ - NCT02333604Recruiting
Cancer experience registry for patients and caregivers
This registry collects information about the experiences of people with cancer and the people who care for them. Joining could help researchers better understand needs and improve support, without requiring cancer treatment changes.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02253251Recruiting
Study genes linked to cancer risk and how they may be affected
This study looks at tiny genetic changes (called microRNA binding site mutations) to understand how they relate to cancer risk, prevention, and treatment. If you (or close family members) have had cancer, and you meet the study’s other requirements, your genetic information could help researchers learn how to better predict and manage cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT02496468Recruiting
Study for children with wheezing or asthma symptoms
This study follows children with wheezing (in younger kids) or doctor-diagnosed asthma (in older kids). It aims to better understand asthma and related breathing problems and how they develop over time.
CologneAges 6 months–18 years - NCT02877706Recruiting
Registry study for newly diagnosed ITP or AIHA
This study is a registry that collects medical information from adults who are newly diagnosed with immune thrombocytopenia (ITP) or autoimmune hemolytic anemia (AIHA), or who are starting a treatment called fosfamatinib. It can help doctors understand these conditions better and improve future care.
ToulouseAges 18 years+ - NCT02846571RecruitingPhase 1/Phase 2
Diabetes cell transplant placed in the eye to restore insulin
This Phase 1/2 study tests whether transplanting insulin-producing cells into the front part of the eye can help people with diabetes. It focuses on people who already have severe, non-usable vision in one eye, to limit risk while the treatment is studied.
Miami, FloridaAges 18–75 - NCT02327884Recruiting
Study saliva and related diseases to learn health patterns
This study looks at diseases that involve the salivary (saliva) glands, and may also include people with active hepatitis, oral cancer, or healthy adults. Researchers collect blood, urine, saliva, and sometimes tissue to better understand what’s happening and how these conditions relate to saliva and oral health.
Bethesda, MarylandAges 4–100 - NCT02835911Recruiting
Lymphoma patient study for people living near Malawi’s main hospital
This is a study that enrolls people with suspected or confirmed lymphoma who come to Kamuzu Central Hospital. It aims to collect lymphoma information (including optional genetic testing of tumor samples) to better understand the disease in Malawi.
LilongweAges birth–99 years - NCT02527486Recruiting
Airways registry study for people with COPD symptoms
This registry collects information from people with COPD (and sometimes overlapping asthma-COPD features) to better understand breathing problems and airways behavior. It may help researchers learn which patterns match different symptom types, without necessarily using a new drug.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
San Francisco, CaliforniaAges 8–35 - NCT02859402RecruitingPhase 2
Donor stem cell transplant for relapsed T or NK lymphoma
This Phase 2 study tests an allogeneic (donor) stem cell transplant for people with T-cell or NK-cell lymphomas that came back or did not respond to prior treatment. It may help by giving you new, healthy immune cells that can attack the cancer.
BusanAges 19–65
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,763 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.