Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT06821360Enrolling by invitation
Confirming type 1 diabetes remotely
This study checks if type 1 diabetes can be confirmed through a remote process rather than in-person visits. It may help make follow-up care easier for people with type 1 diabetes.
Exeter, DevonAges 18 years+ - NCT06812767Enrolling by invitation
Chronic disease risks in working-age people
This study looks at risk factors for chronic diseases in healthy working-age adults. You may help researchers understand how to prevent conditions like heart disease or diabetes.
MoscowAges 18 years+ - NCT06811740Enrolling by invitation
Treating severe asthma by focusing on key health issues
This trial looks at people with severe asthma that is hard to control. It aims to find and treat specific health problems that make asthma worse, by doing a detailed check-up and using treatments that are right for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06786546Enrolling by invitation
Type 1 Diabetes and Blood Vessel Health Study
This study looks at how blood vessels and nerves work in people with Type 1 diabetes compared to healthy volunteers. It may help explain how diabetes affects heart and blood vessel health.
Austin, TexasAges 18–70 - NCT06763783Enrolling by invitationPhase 4
Shingles vaccine study for people with rheumatic diseases
This study offers the Shingrix shingles vaccine for free to adults with inflammatory rheumatic diseases. It compares how well the vaccine works in people taking immune-suppressing drugs versus those not taking them.
LundAges 18 years+ - NCT06756581Enrolling by invitation
Baked dairy trial for children with eosinophilic esophagitis
This trial tests whether children with eosinophilic esophagitis triggered by cow's milk can safely eat baked dairy foods. If you are in remission on a milk-free diet, you may be able to add baked milk products back into your diet.
JerusalemAges Up to 18 years - NCT06746077Enrolling by invitation
Lung disease study in children: new ways to understand infections
This study explores how the immune system and lung microbes affect children with lung disease. It uses extra fluid collected during a standard lung exam to look for new treatment targets.
Aarhus NAges birth–17 years - NCT06744569Enrolling by invitationPhase 1
Testing a new ointment for atopic dermatitis in healthy adults and patients
This trial tests a new ointment called CU-10101. It will first be tested in healthy volunteers to check safety, and then in people with atopic dermatitis (eczema) to see how well it works for mild to moderate symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06730906Enrolling by invitation
PACTAID app for managing exercise in type 1 diabetes
This study tests an app called PACTAID that helps adults with type 1 diabetes manage their blood sugar during exercise. You will try three different types of workouts to see how well the app works.
Rochester, MinnesotaAges 18–65 - NCT06728904Enrolling by invitation
High-intensity Tai Chi for mild to moderate asthma
This trial tests if a high-intensity Tai Chi program can help people with mild to moderate asthma. It aims to improve lung function and control asthma symptoms.
ShanghaiAges 18 years+ - NCT06726096Enrolling by invitationPhase 3
Trial of VDJ001 for moderate to severe rheumatoid arthritis
This trial tests a new medicine called VDJ001 for people with moderate to severe rheumatoid arthritis who are already taking methotrexate. The goal is to see if VDJ001 helps reduce joint pain and swelling better than a placebo.
Beijing, Beijing MunicipalityAges 18–75 - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06711679Enrolling by invitationPhase 4
Finding the right dose of numbing medicine for lower body surgery
This study is testing different amounts and strengths of a numbing medicine called ropivacaine to find the best dose for blocking pain in the lower body during surgery. It may help patients need less pain medicine after surgery.
Wuhan, HubeiAges 1 day–7 years - NCT06698211Enrolling by invitation
Posaconazole to prevent fungal infection in stem cell transplant patients with gut GVHD
This trial tests if giving the antifungal drug posaconazole as a tablet can prevent serious fungal infections in people who have had a stem cell transplant and develop gut graft-versus-host disease (GVHD), which is a complication where donor cells attack the digestive tract. It may help protect patients who need strong immune-suppressing treatment for GVHD.
TianjinAges 18–75 - NCT06693856Enrolling by invitation
Steroid pulse therapy for active Graves' eye disease
This study tests whether high-dose steroid pulses (given through a vein) can help people with moderate to severe Graves' eye disease that is still active. It is for people who have not yet been treated with steroids and whose eye problems began within the past year.
Shanghai, Shanghai MunicipalityAges 25–70 - NCT06691464Enrolling by invitation
Using FAPI PET/CT to find lung scarring in non-healing ARDS
This study uses a special PET/CT scan to look for active scar tissue (fibrosis) in the lungs of people who are still very sick with ARDS after 5 days of ventilator support. It may help doctors understand why some lungs don't heal and could guide future treatments.
Groningen, Provincie GroningenAges 20 years+ - NCT06676566Enrolling by invitation
Follow-up and early detection for kids at risk of type 1 diabetes
This study follows children who are at genetic risk for type 1 diabetes or have early immune signs (autoantibodies) but do not yet need insulin. It provides extra checkups and information to catch the disease early and help families understand their child's risk.
MalmöAges birth–18 years - NCT06674577Enrolling by invitationPhase 2
Long-term safety study of atacicept for IgA nephropathy
This study looks at the long-term safety and effectiveness of atacicept in people with IgA nephropathy (IgAN) who have already completed treatment in a previous atacicept study. It is for patients who want to continue their care and see how well the medicine works over more time.
Brisbane, CaliforniaAges 18–99 - NCT06670651Enrolling by invitation
Study of a new total knee replacement system
This trial is testing a new knee replacement system called LinkSymphoKnee. It is for people needing a first-time total knee replacement to help reduce pain and improve function.
Birmingham, AlabamaAges 18–79 - NCT06665490Enrolling by invitation
Skin care wash study for mycosis fungoides
This study tests whether a special skin care body wash can improve skin lesions in people with mycosis fungoides, a type of skin lymphoma. Researchers will look at skin bacteria before and after using the wash.
Chicago, IllinoisAges 18–89 - NCT06650358Enrolling by invitation
Outcomes for patients with LAL+ lens implants
This study looks at how the LAL+ lens implant performs in people who have had cataract surgery in both eyes and have completed light adjustments for the LAL+ lens. It aims to gather information on vision results and safety.
Wilkes-Barre, PennsylvaniaAges Any age - NCT06643858Enrolling by invitation
Normal Chinese Lifespan Brain Chart Study
This study creates a 'normal brain map' by taking MRI scans of healthy people of all ages. It helps doctors understand what a healthy brain looks like at different stages of life.
Beijing, Beijing MunicipalityAges 6–90 - NCT06637254Enrolling by invitationPhase 2
Testing an oral tablet for hard-to-control asthma
This study tests an oral tablet (HSK31858) to see if it helps control asthma in people whose asthma is not well managed with current inhalers. It focuses on those with a specific type of asthma where certain blood cells are low.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06618339Enrolling by invitation
Mindfulness training for young university students
This trial tests whether a mindfulness program can improve brain function and mental well-being in university students. It may help if you're interested in learning meditation techniques to support your mental health.
Mexicali, Estado de Baja CaliforniaAges 18–30
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.