Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT06640660Recruiting
Study of vision, thinking, and emotions in MS and West Nile
This study looks at how multiple sclerosis or West Nile virus affects visual thinking and mood, and whether a rehab program might help. If you have one of these conditions and can see and use your hands, you may be able to join.
Lido, VeneziaAges 20–85 - NCT07713940Recruiting
Anti-inflammatory diet study for lupus patients
This study tests whether an anti-inflammatory diet can help people with lupus who are on certain medications. It focuses on reducing pain and improving quality of life over 12 weeks.
La Jolla, CaliforniaAges 18 years+ - NCT07714863Recruiting
Can machine learning predict ABPA recurrence?
This study uses a computer model to see if it can predict when ABPA (a lung condition) might come back. If you have ABPA and are stable after treatment, this could help doctors monitor you better.
Jinan, ShandongAges 18 years+ - NCT07708987RecruitingPhase 2
Withaferin-A for steroid-resistant graft-versus-host disease
This trial tests a plant-based medicine, Withaferin-A, in people whose graft-versus-host disease (GVHD) after a stem cell transplant has not responded to steroid treatment. GVHD is a condition where donated immune cells attack the body; this study aims to see if Withaferin-A can help control it.
Navi Mumbai, MaharashtraAges 12–65 - NCT07714044Recruiting
Genetics of blood cancers study
This study looks at the genes that may be linked to blood cancers. You provide a saliva sample and answer a health survey at home, and your DNA may help researchers understand why some people get blood cancers.
Piscataway, New JerseyAges 18–110 - NCT07707739Recruiting
Plasma exchange for children with autoimmune encephalitis
This trial tests whether plasma exchange (a procedure that cleans the blood) can help children with a severe form of autoimmune encephalitis—a condition where the immune system attacks the brain. It's for children who haven't gotten better with standard treatments like steroids or IVIG.
Shibīn al Kawm, Menoufia GovernorateAges 1 month–18 years - NCT07710105Recruiting
Ocrevus for MS: A Real-World Study
This study will follow people with multiple sclerosis (MS) who are starting or restarting a treatment called Ocrevus (ocrelizumab). The goal is to understand how well it works in real life over 12 months. Participants will receive Ocrevus as part of their usual care and complete surveys about their experience.
Chicago, IllinoisAges 18 years+ - NCT07708467Enrolling by invitation
Esophageal function study in eosinophilic esophagitis
This study looks at how the esophagus stretches and moves in people with eosinophilic esophagitis (EoE) who still have symptoms even though their inflammation is under control. The goal is to better understand why symptoms persist and find better ways to measure them.
Milan, MIAges 18 years+ - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT07712809Enrolling by invitation
Testing a connected care platform for kids with type 1 diabetes
This study tests a new online platform that connects your child's diabetes devices (glucose monitor and insulin pump) with their healthcare team. The goal is to help doctors and nurses see your child's data in real time and provide better care.
Vancouver, British ColumbiaAges 3–18 - NCT07713498Enrolling by invitation
Lowering inhaled steroids for tezepelumab-treated asthma patients
This trial looks at whether people with severe asthma who are taking the biologic tezepelumab can safely reduce their use of inhaled corticosteroids (ICS). It aims to see if reducing or stopping ICS affects asthma symptoms or flare-ups.
Rotterdam, South HollandAges 18 years+ - NCT05811013Recruiting
Static magnetic brain stimulation for progressive multiple sclerosis
This trial studies whether a noninvasive brain stimulation approach using a static magnetic field can help people with progressive multiple sclerosis. It aims to improve progressive nerve function while keeping other treatments stable.
Pozzilli, IserniaAges 18–65 - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT06644443RecruitingPhase 1/Phase 2
BCMA-GPRC5D CAR-T cells for relapsed multiple myeloma
This trial tests a new kind of immunotherapy that uses your own immune cells, called CAR-T cells, to target two specific markers (BCMA and GPRC5D) found on myeloma cells. It's for people whose multiple myeloma has come back or stopped responding to earlier treatments.
Shenzhen, GuangdongAges 18–75 - NCT06640309RecruitingPhase 2
Nicotinamide for rheumatoid arthritis: a clinical trial
This trial tests if taking a vitamin B3 supplement (nicotinamide) can improve outcomes for people with rheumatoid arthritis. Researchers want to see if adding this over-the-counter vitamin to your usual arthritis medicines helps reduce disease activity.
CairoAges 18–65 - NCT07705737RecruitingPhase 2
Testing Rademikibart for asthma or COPD flare-ups
This trial tests an investigational drug called Rademikibart for people having a severe asthma or COPD flare-up that needs emergency care and steroids. The study aims to see if the drug can help control the flare-up faster and reduce the need for more treatment.
Miami, FloridaAges 18–85 - NCT07698600RecruitingPhase 1
Safety test of a new HIV vaccine in adults with or without HIV
This study tests a new RNA-based vaccine called BNT168 to see if it is safe and how the body responds to it. It is for healthy adults with or without HIV, and those with HIV will pause their regular treatment for a while during the study.
Houston, TexasAges 18–50 - NCT07704580RecruitingPhase 1/Phase 2
Sarilumab for active rheumatoid arthritis
This trial tests sarilumab, an injected antibody that blocks a key protein involved in inflammation, for people with moderate-to-severe rheumatoid arthritis (RA) who haven't had success with standard treatments. The goal is to see if adding sarilumab can help control joint pain and swelling.
Centennial, ColoradoAges 18 years+ - NCT07701954RecruitingPhase 1
Testing a new drug for people with allergies and high IgE
This early-phase trial tests a new medication, LCA-0061, in healthy people with high IgE levels (a sign of allergies). Part B specifically includes those with a peanut allergy. The study aims to see how safe the drug is and how the body processes it.
Mississauga, OntarioAges 18–55 - NCT07700238RecruitingPhase 3
Romiplostim plus steroids vs steroids alone for newly diagnosed ITP
This trial tests if adding romiplostim (a drug that helps make platelets) to standard steroid treatment works better than steroids alone for adults who have not been treated for ITP before. It is for people with low platelet counts and may help reduce bleeding.
Long Beach, CaliforniaAges 18–100 - NCT07704814Recruiting
Kids' lymph node ultrasound in lower body
This study uses a bedside ultrasound to check lymph nodes in the lower belly and groin of children who come to the emergency room with injuries. It aims to learn what normal lymph nodes look like in healthy kids.
SunderlandAges 2–16 - NCT07706114Enrolling by invitation
Walking with FES: a daily life study for MS
This trial tests whether daily use of Functional Electrical Stimulation (FES) can improve real-world walking and daily activities for people with multiple sclerosis. FES uses small electrical pulses to help weak leg muscles move.
San Francisco, CaliforniaAges 22–75 - NCT07704164RecruitingPhase 2
Colchicine to lower heart artery swelling in HIV
This trial tests if colchicine, a medicine for inflammation, can reduce swelling in the heart arteries of people with HIV. It may help lower the risk of heart problems in those already on a statin or similar medication.
BarcelonaAges 50 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.