Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,227 recruiting studies in this area right now.
By phase
- Not applicable3,140
- Phase 21,067
- Phase 1822
- Phase 1/Phase 2446
- Phase 3423
- Phase 4236
- Phase 2/Phase 393
Top conditions
- Multiple Sclerosis342
- Multiple Myeloma333
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis142
- Type 1 Diabetes132
- Atopic Dermatitis128
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia123
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Leukemia64
- Rheumatoid Arthritis (RA)64
- Acute Myeloid Leukemia62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- Novartis Pharmaceuticals65
- M.D. Anderson Cancer Center63
- AstraZeneca57
- City of Hope Medical Center46
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California492
- Maryland196
- Alabama176
- Florida143
- Arizona140
- New York122
- Massachusetts119
- Texas118
- Illinois82
- Colorado77
Recruiting studies6,227 total
- NCT07713940Recruiting
Anti-inflammatory diet study for lupus patients
This study tests whether an anti-inflammatory diet can help people with lupus who are on certain medications. It focuses on reducing pain and improving quality of life over 12 weeks.
La Jolla, CaliforniaAges 18 years+ - NCT07618936Recruiting
PD-L1 PET/CT imaging scan for cancer patients
This trial tests a new type of imaging scan (PD-L1 PET/CT) that may help doctors better see and understand cancers. The scan uses a special tracer to highlight cancer cells in your body, which could help guide treatment decisions.
Hefei, AnhuiAges 18–80 - NCT07633327Recruiting
How immune cells respond during digestive surgery
This study watches how your body's immune system responds during and after digestive surgery. Researchers will collect samples to understand inflammation patterns, which could help doctors better care for surgical patients in the future.
Nice, Alpes-MaritimesAges 18–80 - NCT07605078Recruiting
How Household Mold Affects Your Health
This study looks at whether mold and toxins in your home are connected to physical and mental health problems. Researchers will analyze dust samples you've already tested to understand these links better.
Richmond, VirginiaAges Any age - NCT07537868RecruitingPhase 2
Montelukast to reduce heart damage after heart attack
This study tests whether montelukast (a medication that reduces inflammation) can limit heart damage when given immediately after a sudden heart attack. Researchers will measure inflammation markers and heart injury to see if this drug helps patients recover better.
Al MansurahAges 30–75 - NCT07473999Recruiting
Vaccine protection in transplant recipients
This study looks at how well vaccines work in people who have received a bone marrow or solid organ transplant. Researchers will track infections and outcomes to understand vaccine effectiveness.
Pavia, LombardyAges Any age - NCT07488728Recruiting
Letermovir to prevent CMV in children after stem cell transplant
This trial tests if the drug letermovir can prevent a common virus (CMV) in children who have certain blood disorders and are getting a stem cell transplant. It aims to keep you safer during recovery.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT07435285Recruiting
Comparing inflammation markers in blood spot vs. vein blood samples
This trial compares two ways of measuring inflammation in the blood: a finger-prick blood spot and a standard blood draw. It may be a good fit if you are getting a seasonal vaccine or have a planned event that causes temporary inflammation, like intense exercise or a change in medication.
Montreal, QuebecAges 18 years+ - NCT07325253RecruitingPhase 2
PET scan study for chronic graft versus host disease
This trial uses a special PET scan to see if we can better understand chronic graft versus host disease (cGVHD), a complication after a stem cell transplant. The study is for people with joint stiffness caused by cGVHD, and it may help doctors find new ways to manage symptoms.
Houston, TexasAges 18 years+ - NCT07289763RecruitingPhase 2
Study of SHR-2173 for primary membranous nephropathy
This trial tests an investigational drug called SHR-2173 for people with primary membranous nephropathy, a kidney disease that causes protein leakage. The study aims to see if the drug is safe and effective, and it involves periodic injections and monitoring.
Nanjing, JiangsuAges 18–75 - NCT07337434RecruitingEarly Phase 1
Comparing two pills for moderate to severe psoriasis
This trial tests two oral medications, Apremilast and Methotrexate, to see which works better for people with moderate to severe plaque psoriasis. You must not have taken systemic treatments (pills or shots that work throughout the body) in the last 3 months.
Peshawar, Khyber PukhtunkhwaAges 18–60 - NCT07252804RecruitingPhase 4
Testing the MenB vaccine safety and immune response in children with rheumatic disease
This trial tests a meningitis B vaccine (MenB-4C) in children and young adults with autoimmune rheumatic diseases. It aims to see if the vaccine is safe and works well for these patients.
São Paulo, São PauloAges 2–25 - NCT07204275RecruitingPhase 2/Phase 3
Testing povetacicept for primary membranous nephropathy
This study tests an investigational drug called povetacicept for people with primary membranous nephropathy, a kidney disease. Researchers want to see if it is safe and helps reduce protein in the urine.
Montgomery, AlabamaAges 18–75 - NCT07206277Recruiting
Using Fibroscan to guide lower anti-rejection medicine after liver transplant
This trial uses a special ultrasound (Fibroscan) to check your liver health and see if you can safely reduce your anti-rejection medications. It is for people who are at least 2 years past a liver transplant and whose liver is working well.
Edmonton, AlbertaAges 18 years+ - NCT07242092RecruitingPhase 4
Pausing methotrexate to boost pneumonia vaccine response
This study tests whether stopping methotrexate for a short time before getting the pneumonia vaccine (PCV20) helps your body build a stronger immune response. It is for people with autoimmune rheumatic diseases like rheumatoid arthritis or lupus whose disease is under control.
São Paulo, São PauloAges 18–100 - NCT07120464Recruiting
Rabies vaccine study for people with weak immune systems or older age
This study tests how well a rabies vaccine works and how safe it is for people whose immune systems may be weaker, such as those with certain long-term illnesses, organ transplants, or age 60 and older. It compares them to healthy adults ages 18 to 59.
Shenzhen, GuangdongAges Any age - NCT07147959RecruitingPhase 2
PET imaging study for rheumatoid arthritis
This trial uses a special PET scan to see how an experimental drug, CIT-013, targets inflammation in the body. It's for people with rheumatoid arthritis to better understand how the drug works.
NijmegenAges 60–85 - NCT07045701Enrolling by invitationPhase 2/Phase 3
Testing FMXIN002 for food allergy reactions
This study is testing a new medicine (FMXIN002) for people who are at risk of a severe allergic reaction to food. If you have a known food allergy and have had a moderate reaction during a food challenge, you may be able to join. The trial will check if the medicine helps prevent or reduce the severity of future reactions.
Be’er Ya‘aqovAges 18–40 - NCT00397280Recruiting
Study of how immune cells react to different stimuli
This study measures how immune cells respond when exposed to test “stimuli.” It needs healthy, nonpregnant adults and screens for certain infections and recent illnesses or medicines to help ensure the results aren’t affected by outside factors.
Research Triangle Park, North CarolinaAges 18–65 - NCT00092235Recruiting
Understanding chronic graft-versus-host disease outcomes
This study follows patients who have had a stem cell transplant and developed chronic graft-versus-host disease (a condition where transplanted cells attack the body). Researchers will track your symptoms and collect blood samples to understand what affects how well patients do over time.
Bethesda, MarylandAges 1–120 - NCT06259071Recruiting
Saliva study for MuSK myasthenia gravis
This study gathers saliva samples from people with MuSK myasthenia gravis to better understand the condition. Participation involves providing a saliva sample and sharing your lab results.
Washington D.C., District of ColumbiaAges 7–99 - NCT07748533RecruitingPhase 1
CAR T-cell therapy for hard-to-treat autoimmune hemolytic anemia
This trial tests a new treatment using your own immune cells (CAR T-cells) to stop them from attacking your red blood cells. It is for people with autoimmune hemolytic anemia or Evans syndrome who have not improved after at least 3 previous treatments.
TianjinAges 18–75 - NCT06116110Recruiting
Long-term follow-up after gene therapy treatment
This study is a long-term follow-up for people who previously received a gene therapy treatment called zamtocabtagene autoleucel in a Miltenyi Biomedicine-sponsored clinical study. It helps researchers monitor your health over time after the treatment.
Gilbert, ArizonaAges 18 years+ - NCT06796504Recruiting
Nerve stimulation for relapsing-remitting multiple sclerosis
This trial tests a device that stimulates a nerve in the neck, which may help repair the protective coating around nerves in the brain and spinal cord. It is for people with relapsing-remitting MS who are stable on their current medication and have some vision problems due to MS.
Irvine, CaliforniaAges 22–60
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,227 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,696 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.