Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,227 recruiting studies in this area right now.
By phase
- Not applicable3,140
- Phase 21,067
- Phase 1822
- Phase 1/Phase 2446
- Phase 3423
- Phase 4236
- Phase 2/Phase 393
Top conditions
- Multiple Sclerosis342
- Multiple Myeloma333
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis142
- Type 1 Diabetes132
- Atopic Dermatitis128
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia123
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Leukemia64
- Rheumatoid Arthritis (RA)64
- Acute Myeloid Leukemia62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- Novartis Pharmaceuticals65
- M.D. Anderson Cancer Center63
- AstraZeneca57
- City of Hope Medical Center46
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California492
- Maryland196
- Alabama176
- Florida143
- Arizona140
- New York122
- Massachusetts119
- Texas118
- Illinois82
- Colorado77
Recruiting studies6,227 total
- NCT05470569Recruiting
Registry study for people with early lupus in Argentina
This is a registry that follows adults with newly diagnosed lupus (within 5 years) to better understand the disease and care needs over time. It may help researchers and doctors learn what to expect early in lupus and improve future treatment planning.
La Plata, Buenos AiresAges 18 years+ - NCT07064330Recruiting
Blood test for immune markers in skin cancer patients on cemiplimab
This trial is testing whether a new blood test can predict how well the drug cemiplimab works for skin cancer and if it causes side effects. It may help doctors better match treatments to patients.
Salamanca, SalamancaAges 18 years+ - NCT05345847Recruiting
Steroid-sparing treatment for immune hepatitis during cancer immunotherapy
This trial studies a way to treat inflammation of the liver (hepatitis) caused by immune cancer medicines (anti-PD-1/PD-L1, sometimes with anti-CTLA-4) without relying on high-dose steroids. It may help reduce steroid side effects while keeping liver inflammation under control.
Calgary, AlbertaAges 18 years+ - NCT07042035Recruiting
A study of once-daily tacrolimus for new lung transplant patients
This trial tests a special form of tacrolimus (Envarsus) taken once daily to prevent organ rejection in people who recently received a first lung transplant. The study will follow patients for at least 12 months.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07020156RecruitingPhase 1
First test of drug OX118 in healthy people
This early-phase trial tests a new drug called OX118 in healthy volunteers to see if it is safe and how the body processes it. It is a first step in developing a potential new treatment.
UppsalaAges 18–60 - NCT06112951Recruiting
ECP treatment for early signs of lung transplant rejection
This trial tests whether a therapy called extracorporeal photopheresis (ECP) can stop early, silent rejection in lung transplant patients. It is for people who have developed donor-specific antibodies but still have normal lung function.
ViennaAges 18 years+ - NCT07321808Recruiting
Shingles vaccine study for frail patients
This study tests how well the shingles vaccine works in people with weakened immune systems due to conditions like rheumatoid arthritis, cancer, or multiple sclerosis. It aims to see if the vaccine is safe and effective for these patients.
Pavia, PaviaAges Any age - NCT07248163Recruiting
Universal CAR-T cell therapy for non-Hodgkin lymphoma
This trial tests a universal CAR-T cell therapy for patients with non-Hodgkin lymphoma whose cancer cells have CD19 on their surface. It might help if standard treatments have not worked.
ShanghaiAges 18 years+ - NCT06391190RecruitingPhase 1/Phase 2
Chemoradiation plus immunotherapy for advanced cervical cancer
This trial tests combining standard chemoradiation with a PD-1 inhibitor (a drug that helps your immune system fight cancer) for advanced cervical cancer that hasn't been treated yet. The goal is to see if this combination works better than standard treatment alone.
ShanghaiAges 18–75 - NCT07024602RecruitingPhase 1
Testing ASC50 tablets for plaque psoriasis
This study tests an investigational tablet called ASC50 for plaque psoriasis. It aims to see if it is safe and works well for people with this skin condition.
Miami, FloridaAges 18–65 - NCT07331103Recruiting
Can a special diet reduce inflammation for heart health?
This study tests whether a special diet can reduce inflammation and improve heart health in people over 55 who are at increased risk for heart disease but have not yet had a heart attack or stroke.
Avellino, AVAges 55 years+ - NCT06479291Recruiting
HCQ plus TPO-RA for ANA positive ITP
This trial tests if combining two medicines (HCQ and a TPO-RA) can help people with a type of low platelet count called ITP who also have a positive ANA blood test. The goal is to see if this combination works better than standard treatments.
Shanghai, Shanghai MunicipalityAges 15–99 - NCT04166656RecruitingPhase 3
Meningococcal B vaccine testing for people without a spleen
This Phase 3 trial tests how safe and how well the immune system responds to three different meningococcal B vaccine approaches in people who do not have a spleen. It may help future adults like you choose a safer, more effective prevention strategy against meningococcal B infection.
ParisAges 18–75 - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT04876781Recruiting
Track safety of Xeljanz XR in Korea
This study collects real-world safety information about Xeljanz XR after it has been approved. It includes people with certain immune-related joint diseases and checks for side effects in everyday use.
SeoulAges 18 years+ - NCT07033663Recruiting
Monoclonal antibody exposure during pregnancy and baby's immune system
This study looks at how monoclonal antibody treatments given during pregnancy affect a baby's immune system development. It compares babies whose mothers received these treatments throughout pregnancy, only in early pregnancy, or not at all.
Esplugues de Llobregat, BarcelonaAges Any age - NCT06896240Recruiting
Fiber smoothie trial for knee replacement patients
This trial tests if drinking a special fiber smoothie for 2 weeks before knee revision surgery can reduce inflammation and improve recovery. It is for people who are scheduled for knee replacement and have certain chronic health conditions.
New York, New YorkAges 40–80 - NCT06645847Recruiting
Ketone drink for walking and strength in older adults
This study tests whether a special ketone drink can help older adults who are starting to feel frail (slower walking, less energy). You would be assigned to one of several groups, and researchers will check if the drink improves your strength and daily function.
Novato, CaliforniaAges 65 years+ - NCT07718555Recruiting
Gut bacteria study for autoinflammatory diseases
This study looks at the gut bacteria (microbiome) in people with autoinflammatory diseases. It may help researchers understand how bacteria in the gut affect inflammation and find better ways to treat these conditions.
ParisAges 12 years+ - NCT07022288Recruiting
Study of La Roche-Posay cream for mild facial eczema
This study tests whether a specific soothing moisturizer (La Roche-Posay B5 cream) helps people with mild, stable facial eczema. It is a simple, low-risk trial using a cream you can apply at home.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07637877RecruitingPhase 2
New Treatments for HIV Patients With Low Immune Cell Counts
This study tests targeted therapies to help HIV patients whose immune systems haven't fully recovered despite years of successful HIV medication. You may qualify if your CD4 count (a measure of immune health) stays low even though your viral load is undetectable.
Beijing, Beijing MunicipalityAges 18–60 - NCT07016152RecruitingPhase 1
A study of a Klebsiella vaccine for healthy adults
This trial tests a new two-part vaccine (CHO-V08) to prevent Klebsiella pneumoniae infection. It looks at safety and immune response in healthy adults aged 18 to 50.
TaipeiAges 18–50 - NCT06100965Recruiting
Lower dose alemtuzumab for kidney transplant rejection
This trial tests a reduced dose of alemtuzumab, a medicine that calms the immune system, for people whose kidney transplant is being rejected and standard treatments haven't worked or aren't safe.
Rotterdam, South HollandAges 18 years+ - NCT07711418RecruitingPhase 3
A study of rezpegaldesleukin for teenagers and adults with moderate-to-severe eczema
This trial tests an investigational drug called rezpegaldesleukin for people aged 12 and older with moderate-to-severe atopic dermatitis (eczema) that hasn't improved enough with topical treatments. The goal is to see if it can safely reduce eczema symptoms.
The Bronx, New YorkAges 12 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,227 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,696 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.