Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT06902012RecruitingPhase 1/Phase 2
Second infusion of CAR-T based on ctDNA for large B-cell lymphoma
This trial tests whether a second infusion of a CAR-T cell therapy called Axi-cel, given early based on a blood test (ctDNA), can help people with relapsed or hard-to-treat large B-cell lymphoma. If you had a partial response or your ctDNA stayed positive after the first dose, you may be eligible.
Guangzhou, GuangdongAges 18 years+ - NCT06560372Recruiting
Bleeding after head injury and brain blood vessel narrowing
This study looks at whether moderate to severe traumatic brain injury with bleeding around the brain can lead to a complication called cerebral vasospasm (narrowing of brain blood vessels). It's being done at Martinique University Hospital to understand how often this happens and how it affects recovery.
Fort-de-FranceAges 18 years+ - NCT06365359Recruiting
Lupus and pesticide exposure in Martinique
This study looks at how exposure to a pesticide called chlordecone might affect people with lupus in Martinique. Researchers want to understand if there is a link between the chemical and lupus symptoms or kidney problems.
Fort-de-FranceAges 18 years+ - NCT00404989Recruiting
Pregnancy drug safety registry for people with HIV treatment
This trial is a pregnancy registry that collects information about birth outcomes when certain HIV medicines are taken during pregnancy. It helps detect any major birth defects so future pregnancies can be safer.
Wilmington, North CarolinaAges 12–60 - NCT04380038RecruitingPhase 4
Viral infection study in well-controlled asthma adults
This study looks at how a viral infection affects people with well-controlled asthma. It tests whether specific asthma-related immune signals can predict who reacts more to a virus, which may help guide future asthma care.
Charlottesville, VirginiaAges 18–40 - NCT05479448Recruiting
Tracking what predicts response in new PMR or GCA
This study looks at people newly diagnosed with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) and uses their health and treatment information to learn what predicts how well treatment works. It may help your care in the future by improving which patients respond best and how.
BaselAges 18 years+ - NCT07246577Recruiting
Improving diagnosis and monitoring in giant cell arteritis
This study uses ultrasound, a biopsy of the temple artery, and blood tests to improve how giant cell arteritis (GCA) is diagnosed, monitored, and predicted. It may help doctors find better ways to manage this condition.
GothenburgAges 18 years+ - NCT07245576Recruiting
Testing new ways to diagnose asthma and COPD in primary care
This study compares simple breathing tests (oscillometry and FeNO) used by your primary care doctor against a specialist's diagnosis to see if they can accurately tell if you have asthma or COPD. If you have symptoms like wheezing, cough, or shortness of breath but haven't been diagnosed yet, this trial may help improve how these conditions are found.
Buenos AiresAges 18 years+ - NCT07247279Recruiting
Study of myasthenia gravis treatments in Russia
This study tracks how generalized myasthenia gravis (a condition that causes muscle weakness) is treated in Russia. By looking at real-world data, researchers hope to learn more about which treatments work best for people like you.
Kazan'Ages 18 years+ - NCT07243782Recruiting
Study of Cosentyx for skin and joint conditions in Korea
This study tracks how well Cosentyx works in real-world use for people with hidradenitis suppurativa, plaque psoriasis, or juvenile idiopathic arthritis. It helps doctors understand the medicine's long-term effects in Korean patients.
Seoul, SeoulAges 6–100 - NCT07239947RecruitingPhase 1
Testing BBT001 for healthy volunteers and people with eczema
This trial tests a new medicine called BBT001, first in healthy people and then in adults with moderate to severe eczema (atopic dermatitis). It aims to see if the drug is safe and how well it works for treating eczema that hasn't improved with topical treatments.
Hefei, AnhuiAges 18–65 - NCT07241546RecruitingPhase 2
Inhaled study drug for people with mild allergic asthma
This trial tests an inhaled drug called ARO-RAGE to see if it can help people with mild asthma who have allergies. You'll take the drug and then do a special breathing test to see how your lungs respond.
Vancouver, British ColumbiaAges 18–65 - NCT07245992RecruitingPhase 1
Study of F8IL10 injections for rheumatoid arthritis
This trial tests if a new drug called F8IL10, given as an injection directly into an inflamed joint, can help people with rheumatoid arthritis. It is for adults who have had RA for more than 6 months and still have joint swelling despite their current medications.
Reggio Emilia, Reggio EmiliaAges 18–80 - NCT07245368RecruitingPhase 1/Phase 2
Testing a new asthma drug in healthy people and those with asthma
This study tests an investigational drug called PRA-216, first in healthy volunteers to check safety, then in people with mild-to-moderate asthma to see if it helps control symptoms. It's an early-stage trial to find out if the drug is safe and works.
Botany, New South WalesAges 18–65 - NCT07246031RecruitingPhase 2
BPC2001 to Prevent Graft-Versus-Host Disease After Stem Cell Transplant
This trial tests a new drug, BPC2001, to see if it can prevent graft-versus-host disease (a common complication where donor cells attack the patient's body) in people receiving a half-matched stem cell transplant from a family donor. It may be an option for adults with certain blood cancers who are planning their first transplant.
Beijing, Beijing MunicipalityAges 18–65 - NCT07248176Recruiting
Universal CAR-T therapy for multiple myeloma
This trial tests a universal CAR-T cell therapy (made from donated cells) for multiple myeloma that has come back after at least two prior treatments. It may be an option if your cancer cells have a specific marker called BCMA and you have not had certain prior therapies.
ShanghaiAges 18 years+ - NCT07248865RecruitingPhase 1
Study of CLYM116 in healthy volunteers
This study tests a new drug called CLYM116 in healthy adults to see how safe it is and how the body processes it. It may help researchers learn more before testing it in people with certain medical conditions.
BrisbaneAges 18–60 - NCT07246564RecruitingPhase 4
Rozanolixizumab for Generalized Myasthenia Gravis in Chinese Adults
This study tests an investigational drug called rozanolixizumab for Chinese adults with generalized myasthenia gravis who have a specific antibody (AChR or MuSK) and symptoms that still affect daily activities. It aims to see if the drug helps improve muscle strength and quality of life.
BeijingAges 18 years+ - NCT06904729RecruitingPhase 3
CAR-T cell therapy for tough lupus kidney disease in children
This trial tests a new type of immune cell therapy (CAR-T cells) for children whose lupus kidney disease (lupus nephritis) has not responded to standard treatments. The CAR-T cells are designed to target and remove certain immune cells that are attacking the kidneys, with the goal of stopping the disease.
Guangzhou, GuangdongAges 6–18 - NCT04662723RecruitingPhase 4
Personalized treatment for IgA kidney disease
This trial tests whether choosing treatment based on your personal kidney findings can improve outcomes in adults with IgA nephropathy (IgAN). It may help by matching therapy to the type and severity of kidney damage seen on biopsy.
Bari, BAAges 18 years+ - NCT07247760Enrolling by invitation
Whitening for white spots on teeth
This trial tests a home whitening gel (10% carbamide peroxide) to see if it can make white spots on front teeth less noticeable and if people are happy with the results. It might help if you have white spots and want a simple way to improve your smile.
Alcorcón, MadridAges 18 years+ - NCT07247734RecruitingPhase 2
Colchicine for insulin sensitivity in type 1 diabetes
This trial tests whether a daily oral medication called colchicine can improve how your body responds to insulin. It is for people with type 1 diabetes who have ongoing low-level inflammation and are already using a continuous glucose monitor.
Gentofte MunicipalityAges 18–80 - NCT07246460Recruiting
Ultrasound and protein tests to see if guselkumab works for Crohn's
This study tests whether guselkumab (a targeted drug) can effectively treat Crohn's disease in the ileum (last part of the small intestine). You will have ultrasound scans and blood tests to measure your response, which may help find the right dose and monitor for bowel healing.
Calgary, AlbertaAges Up to 80 years - NCT07249528Recruiting
Using voice recordings to monitor side effects during CAR T-cell therapy
This study tests if daily voice recordings on a smartphone can help detect side effects early in people receiving CAR T-cell therapy for non-Hodgkin lymphoma or multiple myeloma. You will make short voice recordings twice a day and have daily neurological checks.
Basking Ridge, New JerseyAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.