Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06843707Recruiting
Lung nodule study using blood and tissue metabolism
This trial follows people with lung nodules over time, using blood and tissue samples to look for metabolic changes that may help understand lung cancer better. If you have a lung nodule found on a CT scan and can safely do lung function tests, this study may be a fit.
Guangzhou, GuangdongAges 18–75 - NCT06844344Recruiting
Testing cryo biopsies for lung lesions
This trial compares a new method called cryo biopsy to standard forceps biopsy for diagnosing lung lesions. It may help get better tissue samples with fewer procedures.
Næstved, Region SjællandAges 18 years+ - NCT06844370Recruiting
Home vs hospital NIV care for MND
This study compares two ways of starting non-invasive ventilation (NIV) — a breathing machine — for people with motor neurone disease (MND). It aims to see if starting NIV at home is as safe and effective as starting it in the hospital.
CambridgeAges 18 years+ - NCT06844916Recruiting
AI to find the best breathing machine settings
This trial tests if artificial intelligence (AI) can help doctors choose the best air pressure settings for people on breathing machines in the ICU. It aims to improve care for adults who need help breathing.
IstanbulAges 18 years+ - NCT06845618Recruiting
Blood test to monitor tuberculosis treatment
This study is looking at how a simple blood test can help monitor tuberculosis (TB) treatment. It may help doctors know sooner if the treatment is working.
TakAges 18 years+ - NCT06846385RecruitingPhase 2/Phase 3
Testing a new shot for severe seasonal hay fever
This study tests a new injection called MG-K10 for people with moderate-to-severe seasonal hay fever that isn't well controlled by standard treatments like nasal sprays or antihistamines. The goal is to see if it can reduce your allergy symptoms over the pollen season.
Beijing, Beijing MunicipalityAges 18–75 - NCT06846554RecruitingPhase 2
Study of APL-9796 for Pulmonary Hypertension with CardioMEMS Monitor
This trial tests a study drug called APL-9796 for people with pulmonary hypertension (PH). It may help by using your CardioMEMS monitor to see how well the drug works. You can take part only if you have a CardioMEMS implant and your PH is not too mild or too severe.
London, LondonAges 18–80 - NCT06846762Recruiting
DNA/RNA co-testing for advanced lung cancer that has stopped responding to first treatment
This study is for people with advanced non-small cell lung cancer whose tumors do not have certain genetic changes (called driver mutations) and whose first treatment did not work well or caused bad side effects within 6 months. The researchers want to use a special test (DNA/RNA-NGS) to look for hidden genetic alterations that might explain why the cancer didn't respond.
Shanghai, Shanghai MunicipalityAges Any age - NCT06847061Recruiting
Pulmonary rehab for rural COPD patients
This study tests a home-based or remote pulmonary rehabilitation program for people with COPD who live in rural areas. The goal is to help you manage your breathing and stay active, all from home without travel to a medical center.
Scottsdale, ArizonaAges 40 years+ - NCT06848309Recruiting
Immune response study for influenza or COVID-19
This study looks at how your immune system fights off flu or COVID-19. If you have a current or recent infection, or if you've been vaccinated in the past year, you may be able to join.
St Louis, MissouriAges 18–60 - NCT06848647Recruiting
Treating sleep apnea to improve metabolism
This study tests whether treating sleep apnea with CPAP improves your body's metabolism (how your body uses energy). It's for people who have sleep apnea and are about to start CPAP therapy.
Uppsala, Uppsala CountyAges 18 years+ - NCT06848699RecruitingPhase 1/Phase 2
Testing HLX43 plus Serplulimab for advanced solid tumors
This trial tests a new combination of two cancer drugs (HLX43 and Serplulimab) for people with advanced solid tumors, especially those with a specific type of lung cancer (NSCLC) that has an EGFR mutation. The goal is to see if this combination can shrink tumors or slow their growth.
Hunan, ChangshaAges 18–75 - NCT06849167RecruitingPhase 2
Immunotherapy with low-dose chemoradiation for advanced lung cancer
This trial tests combining immunotherapy with a shorter course of chemoradiation for locally advanced non-small cell lung cancer that hasn't spread. It aims to see if this approach is more effective and tolerable than standard treatment.
BeijingAges 18–70 - NCT06849518Recruiting
Blood test to track immunotherapy response in lung cancer
This study is looking at a simple blood test to see if it can help track how well your immunotherapy is working. If you have advanced lung cancer and are getting a standard immunotherapy drug, you may be able to join.
Kingsport, TennesseeAges Any age - NCT06849596Recruiting
Breathing help for extremely premature babies at birth
This study compares two ways to help extremely premature babies breathe right after birth: using a manual T-piece or a ventilator. The goal is to find which method is safer and more effective.
Los Angeles, CaliforniaAges 6 months–7 months - NCT06850220Recruiting
How sleep apnea affects thinking and empathy in kids
This study looks at how obstructive sleep apnea caused by enlarged tonsils or adenoids might affect a child's thinking skills and ability to understand others. It will help doctors learn if treating the sleep problem could also help with these skills.
Suzhou, JiangsuAges 3–12 - NCT06850298Recruiting
H5N1 milk detection study
This study looks for the H5N1 virus in the milk of healthy adults. If you are generally healthy and between 18 and 64, you may be able to help by providing milk samples to see if the virus can be detected.
Atlanta, GeorgiaAges 18–64 - NCT06850350Recruiting
Long COVID and Thinking & Walking
This study looks at how Long COVID affects thinking and movement skills. If you had COVID-19 more than 3 months ago and could walk before you got sick, you may be able to help researchers understand these lasting symptoms.
Chicago, IllinoisAges 18 years+ - NCT06850792Recruiting
Improving treatment adherence with telemedicine and guidance
This study tests whether regular remote check-ins and guidance can help people with pulmonary arterial hypertension stick to their treatment plan. You would be followed by phone or video from University of Sao Paulo.
São Paulo, São PauloAges 18 years+ - NCT06850961Recruiting
Digital health app for COPD self-management
This study tests a digital health app to help you manage COPD symptoms on your own. It focuses on people who have trouble with mucus and want to use a smartphone for their care.
Bergen, NorwayAges 18–90 - NCT06851338Recruiting
Inspire therapy study for teens with Down syndrome and sleep apnea
This study tests a device called Inspire that stimulates the airway during sleep to treat obstructive sleep apnea in teenagers with Down syndrome who cannot use a CPAP machine or had a tonsillectomy that did not work well.
Phoenix, ArizonaAges 13–18 - NCT06851663RecruitingPhase 2/Phase 3
New PET scan for many solid tumors
This trial tests a new type of PET scan that uses a special antibody to find a marker called Trop2 on many common solid tumors. It may help doctors see tumors more clearly without needing a biopsy.
ShanghaiAges 18–75 - NCT06851715Recruiting
Improving quality of life for teens with asthma
This study tests a program to help teenagers with asthma feel better and have fewer symptoms. It focuses on improving day-to-day quality of life by providing extra support in a respiratory clinic.
Southampton, HampshireAges 12–18 - NCT06852911Recruiting
New FeNO device for asthma diagnosis
This study tests a new device that measures a lung marker called FeNO (fractional exhaled nitric oxide) to help diagnose asthma. It may be an option for adults with asthma who have not changed their medication recently and have no recent infections.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.