Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06853145RecruitingEarly Phase 1
Using a special MRI scan to study lung disease in IPF
This trial uses an advanced MRI technique with a special gas (hyperpolarized xenon-129) to look at lung function in people with idiopathic pulmonary fibrosis (IPF). It may help doctors better understand how the disease affects your lungs and could lead to improved care.
Charlottesville, VirginiaAges 18 years+ - NCT06853223RecruitingPhase 2
Immune drug to prevent lung transplant failure
This trial tests an immune-suppressing medicine to stop a serious complication called primary graft dysfunction that can happen soon after a lung transplant. It may help people who are already on the transplant waiting list and plan to receive a standard anti-rejection drug regimen.
San Francisco, CaliforniaAges 18 years+ - NCT06853834Recruiting
Comparing two biopsy methods for suspected sarcoidosis
This trial compares two ways of taking a lung tissue sample (cryo biopsy vs forceps biopsy) in people who may have sarcoidosis. The goal is to see which method is better at diagnosing the condition.
Lucknow, Uttar PradeshAges 18 years+ - NCT06854380RecruitingEarly Phase 1
Steroid and enzyme injection for vocal cord lesions
This trial tests if injecting a steroid combined with hyaluronidase into vocal cord lesions can help people with voice problems who cannot or will not do voice therapy. It's for those with small, non-cancerous growths who aren't candidates for surgery.
Al Mansurah, Dakahlia GovernorateAges 18–60 - NCT06854627Recruiting
Comparing two ways of lying face down for ARDS patients
This study compares lying face down continuously for a long time versus lying face down for shorter periods each day. It is for patients with moderate to severe ARDS (a serious lung condition) who are on a breathing machine. The goal is to see which approach helps the lungs recover better.
Buenos AiresAges 18 years+ - NCT06855771RecruitingPhase 2
Study of an oral drug for MTAP-deleted advanced lung cancer
This study tests an experimental oral medication (navlimetostat) for people with advanced lung cancer whose tumors have a specific genetic change called an MTAP deletion. It’s for those whose cancer has progressed after earlier treatments.
Anchorage, AlaskaAges 18 years+ - NCT06857890RecruitingPhase 1
Safety study of Grammidin throat spray in healthy volunteers
This trial tests a new throat spray called Grammidin With Anesthetic to see if it is safe and how the body processes it. Healthy volunteers take the spray and are monitored for side effects and drug levels in the blood.
MoscowAges 18–45 - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT06859281RecruitingPhase 1
Safety of Grammidin throat spray in healthy adults
This trial tests the safety and how the body processes a new throat spray called Grammidin. Healthy volunteers will use the spray so researchers can see how it works and if there are any side effects.
Saint PetersburgAges 18–45 - NCT06859333RecruitingPhase 1
Safety study of Ingavirin Forte in healthy volunteers
This trial tests how safe and tolerable different doses of Ingavirin Forte are in healthy people. It helps find the right dose for future studies.
MoscowAges 18–45 - NCT06861088RecruitingPhase 3
Kinisoquin for preventing blood clots in pancreatic cancer
This trial tests whether an investigational drug called Kinisoquin™ can help prevent blood clots in people with advanced pancreatic cancer who are starting their first chemotherapy. It may be a good option if you are looking for extra protection against clots during treatment.
Ventura, CaliforniaAges 18 years+ - NCT06861543RecruitingPhase 1
TMT101 for advanced pancreatic or lung cancer
This trial tests a new drug called TMT101 for people with advanced pancreatic cancer or non-small cell lung cancer who have already tried other treatments. The goal is to see if TMT101 is safe and works against the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06861686Recruiting
New classification for obstructive sleep apnea
This study is improving how doctors classify obstructive sleep apnea (a condition where your breathing stops and starts during sleep). It focuses on sleepiness and heart-related risks to help guide treatment. If you are 40 or older and have untreated OSA, you may be able to join.
Antwerp, AntwerpAges 40 years+ - NCT06862297Recruiting
Comparing a new jaw tracking device to standard sleep study for sleep apnea
This study compares a new device that tracks jaw movement during sleep to the standard sleep study (polysomnography) for diagnosing sleep apnea. You may be eligible if you have symptoms like loud snoring or daytime sleepiness and have been referred for a sleep study.
TaipeiAges 20–75 - NCT06862895Recruiting
Chest therapy for babies with bronchiolitis
This trial tests whether gentle chest physiotherapy can help babies with bronchiolitis (a lung infection) recover better. It looks at how the therapy affects their breathing and overall health.
Erbil, KurdistanAges 1 month–1 year - NCT06863506RecruitingPhase 2
Study of Befotertinib for non-small cell lung cancer with uncommon EGFR mutations
This trial tests a drug called Befotertinib for people with non-small cell lung cancer that has uncommon EGFR mutations (like G719X, L861Q, S768I, or exon 20 insertions). It is for those who haven't taken an EGFR-targeted pill before and have had a previous chemotherapy stopped working or caused side effects.
Hangzhou, ZhejiangAges 18 years+ - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT06865118Recruiting
Home management of heart issues in scleroderma
This study tests whether people with systemic sclerosis (scleroderma) and pulmonary arterial hypertension (PAH) can safely monitor their heart health at home using a smartphone or other internet-connected device. If you have PAH and are comfortable using technology, this trial may help make care more convenient.
OsloAges 18 years+ - NCT06866652Recruiting
Why Am I Short of Breath? A Study in Myasthenia Gravis
This study looks at why people with myasthenia gravis (MG) feel short of breath. It aims to understand breathing problems that happen in daily life, even when MG seems stable.
ParisAges 18 years+ - NCT06866717Recruiting
Exercise before lung cancer surgery
This trial tests whether doing exercise training before lung cancer surgery can help you recover better. It is for people with low fitness levels who live with another adult at home.
RouenAges 18 years+ - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06868433RecruitingPhase 1
TMV vaccine alone or with pembrolizumab for advanced HNSCC
This trial tests a vaccine made from your own tumor to help your immune system fight head and neck cancer that has returned or spread. It is given alone or with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors or slow progression.
Atlanta, GeorgiaAges 18 years+ - NCT06868485RecruitingPhase 2
Study of WSD0922-FU for advanced lung cancer with C797S mutation
This trial tests a new drug, WSD0922-FU, for people with advanced non-small cell lung cancer that has a specific genetic change called C797S. It is for those whose cancer has gotten worse after treatment with osimertinib.
Oxnard, CaliforniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.