Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06829784RecruitingPhase 3
Study of TQC2731 for severe asthma
This trial tests an investigational drug called TQC2731 for people with severe asthma that is not well controlled despite high-dose inhaled steroids. The study aims to see if this treatment can reduce asthma attacks.
Bozhou, AnhuiAges 18–75 - NCT06830109RecruitingPhase 2
Testing a nasal spray for stuffy nose relief
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
St Louis, MissouriAges 18 years+ - NCT06830174Recruiting
tDCS Brain Stimulation for Laryngeal Dystonia
This study tests whether a gentle brain stimulation technique called tDCS can help improve voice control in people with laryngeal dystonia. It aims to find a new way to reduce muscle spasms in the voice box.
New Haven, ConnecticutAges 18–65 - NCT06830694RecruitingPhase 2
Trial of a new drug combo for a rare type of lung cancer
This trial tests a new drug (tarlatamab) combined with chemotherapy and immunotherapy for people whose lung cancer has changed from one type (adenocarcinoma) to small cell lung cancer after treatment with EGFR targeted therapy. The goal is to see if this combination is safe and works well.
Seoul, Gangnam-guAges 19 years+ - NCT06832163Recruiting
Smart weaning from inhaled nitric oxide for newborns with PPHN
This trial tests a new, smart way to slowly reduce (wean) the inhaled nitric oxide gas that helps babies with a serious lung condition called PPHN. If your baby is already responding well to iNO and needs it for at least 24 hours, this study might help make the weaning process safer and more effective.
ShanghaiAges Any age - NCT06833229Recruiting
Can a PET scan predict if immunotherapy is working?
This study uses a special PET-CT scan early in your treatment to see if immunotherapy (with or without chemotherapy) is working against your advanced lung cancer. The goal is to find out faster if the treatment is helping.
NiceAges 18 years+ - NCT06833632Recruiting
Studying cancer cells in the blood and air spaces for early lung cancer
This study looks for cancer cells that travel through the blood or spread through air spaces in the lungs of people with early-stage lung cancer. The goal is to understand how these cells affect the disease, and it may help doctors plan better treatment in the future.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+ - NCT06834971Recruiting
Inhaled colistin to prevent pneumonia in ventilated patients
This trial tests if inhaling a medication called colistin can prevent ventilator-associated pneumonia (a lung infection) in patients who are on a breathing machine. It aims to reduce the risk for those at high risk of getting an infection from drug-resistant bacteria.
Jinan, ShandongAges 18 years+ - NCT06835569RecruitingPhase 1
ALTA3263 for advanced KRAS-mutated solid tumors
This trial tests an experimental pill called ALTA3263 for adults with advanced solid tumors that have a specific KRAS mutation. It's for people who have already tried other treatments or can't take them.
Orlando, FloridaAges 18 years+ - NCT06835842Recruiting
Rib mobilization for pneumonia patients on a ventilator
This study tests whether a gentle rib movement technique (called rib mobilization) can help people with pneumonia who are on a breathing machine get ready to breathe on their own. It aims to see if this therapy makes it easier to wean off the ventilator.
CairoAges 40–50 - NCT06836453Recruiting
New sweat test for cystic fibrosis diagnosis
This trial tests a new device that measures how your sweat glands react to a common asthma medication. It aims to better classify people with cystic fibrosis or related diseases, and also includes healthy volunteers and carriers.
BrusselsAges Any age - NCT06836830Recruiting
Comparing Two Ventilator Settings After Cardiac Arrest
This study compares two ways of setting the breathing machine for people who suffer a cardiac arrest outside the hospital. It looks at whether using a small amount of extra pressure (called PEEP) improves outcomes compared to using no extra pressure (ZEEP).
Gütersloh, North Rhine-WestphaliaAges 18 years+ - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Birmingham, AlabamaAges 12 years+ - NCT06838208RecruitingPhase 2
Immunotherapy plus chemo and radiation for first-line extensive-stage small cell lung cancer
This study tests a combination of an immunotherapy drug (tislelizumab) plus chemotherapy followed by targeted chest radiation as the first treatment for extensive-stage small cell lung cancer. The goal is to see if adding radiation after chemo-immunotherapy works better than standard treatment alone.
Hefei, AnhuiAges 18 years+ - NCT06837922RecruitingPhase 3
Study of MG-K10 for moderate to severe asthma
This trial tests a new drug called MG-K10 for people with moderate to severe asthma that is not well controlled with current treatments. It aims to see if the drug can reduce asthma attacks and improve breathing. You may be able to join if you have had asthma for at least a year, use high-dose inhalers plus another controller medicine, and have had a recent flare-up.
Guangzhou, GuangdongAges 12–75 - NCT06838273RecruitingPhase 3
Testing a new drug combo for EGFR-mutated lung cancer
This trial tests a new combination of two drugs (BL-B01D1 and osimertinib) versus osimertinib alone as the first treatment for people with a specific type of advanced lung cancer that has an EGFR mutation. The goal is to see if the combination works better at stopping the cancer from growing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06839105RecruitingPhase 1
Testing AWT020 for advanced cancers
This study tests an experimental drug called AWT020 in people with advanced cancers that have either stopped responding to standard treatments or aren't candidates for them. The goal is to see if AWT020 is safe and tolerable across several cancer types such as lung cancer, melanoma, colorectal cancer, kidney cancer, and others.
Fuzhou, FujianAges 18 years+ - NCT06839248Recruiting
Fasting before procedures with GLP-1 meds
This study looks at whether people taking weekly GLP-1 medications (like Ozempic or Wegovy) should follow standard fasting rules or a 24-hour clear liquid diet before a procedure. The goal is to find the safest way to prepare.
Melbourne, VictoriaAges 18 years+ - NCT06840704RecruitingPhase 3
Can immunonutrition reduce esophagitis during lung cancer radiation?
This trial tests if a special nutritional supplement (immunonutrition) can lower the risk of severe throat and chest irritation (esophagitis) caused by radiation therapy for lung cancer. You may qualify if you are about to start chest radiation and can eat normally.
Changsha, HunanAges 18 years+ - NCT06841055RecruitingPhase 2
Pumitamig plus chemo for Stage IV lung cancer after immunotherapy
This trial tests a new investigational drug called Pumitamig (BNT327) given with chemotherapy for people with advanced non-small cell lung cancer (Stage IV) that has continued to grow after one prior treatment with immunotherapy and platinum chemotherapy. The study aims to see if this combination is safe and can help shrink the cancer.
Birmingham, AlabamaAges 18 years+ - NCT06841770RecruitingPhase 1
Testing a delivery device for spinal cord injury treatment
This trial tests a device that delivers a special cell therapy (LCTOPC1) into the spinal cord. It is for people with a recent or chronic spinal cord injury that is severe (no feeling or movement below the injury) or leaves some sensation but no movement.
Downey, CaliforniaAges 18–65 - NCT06841913RecruitingPhase 4
Woodsmoke, flu, and your nasal immune response
This study tests how breathing woodsmoke affects your nose's ability to fight off the flu virus. You will be exposed to woodsmoke and then given a live flu vaccine to see how your immune system responds.
Chapel Hill, North CarolinaAges 18–49 - NCT06843018RecruitingPhase 2
Spray vs lozenge for sore throat from infection
This trial tests a new spray with anesthetic for sore throat caused by infections like pharyngitis. It compares the spray to a lozenge (Septolete Total) to see which works better and is safer.
Engel'sAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.