Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06629558Recruiting
A less invasive treatment for severe emphysema
This trial tests a bronchoscopic procedure to reduce lung volume in patients with severe emphysema that is patchy (not spread evenly). The goal is to help you breathe better without the need for surgery.
Al MansurahAges 40–75 - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT06683781Recruiting
Breathing machine settings and weaning success study
This study looks at how breathing machine settings and monitoring can help predict if a patient will successfully come off the ventilator. It may help doctors choose better settings for patients who are ready to try breathing on their own.
Buenos AiresAges 18–100 - NCT06678243Recruiting
Smartphone app to help occasional smokers quit
This study tests a smartphone app (SiS4) designed to help people who smoke occasionally but not daily to quit. You will use the app to track your smoking and get support tailored to your schedule.
Boston, MassachusettsAges 18 years+ - NCT06642376Recruiting
Breathing exercise for ICU nurses: stress and fatigue
This study tests whether a simple breathing exercise can help reduce fatigue and stress in intensive care nurses. If you work in an ICU and are interested in trying a short, guided breathing technique, this could be a low-effort way to feel better.
KahramanmaraşAges 18 years+ - NCT06647836Enrolling by invitation
Immunotherapy for advanced lung squamous cancer
This trial tests how well immunotherapy works as a first treatment for advanced lung squamous cell carcinoma, either alone or with chemotherapy. It aims to see if this approach can help patients who haven't had prior cancer treatment.
Wuhan, HubeiAges 18–80 - NCT06595602Recruiting
Intelligent lung support in the ICU
This trial tests a smart breathing machine that adjusts support automatically for people on a ventilator. It may help make breathing more comfortable and reduce lung injury.
DresdenAges 18 years+ - NCT06583616Recruiting
Can blood gas levels predict survival after a pulmonary embolism?
This study looks at whether a simple blood test (the anion gap) can help predict survival in patients with acute pulmonary embolism. It aims to find out if this measurement can guide treatment decisions.
Semarang, Central of JavaAges 18–70 - NCT06554275Recruiting
CCHS research health hub
This study creates a secure health information hub for people with Congenital Central Hypoventilation Syndrome (CCHS) to help researchers better understand the condition and find new ways to treat it. Being part of this hub may help advance future studies and care options for CCHS.
Chicago, IllinoisAges Any age - NCT06576596Recruiting
Oxygen during breathing tube placement in children
This study tests a method to keep children breathing easily while their airway is being prepared for surgery. It may help children who are 0-6 years old and having planned surgery under general anesthesia.
Heidelberg, Baden-WurttembergAges birth–6 years - NCT06534840Recruiting
Predicting lung problems after liver transplant
This study uses a computer program to predict lung problems after a liver transplant. It may help doctors better care for people like you.
Chengdu, SichuanAges 18–80 - NCT06552013Recruiting
Asthma study for kids in Georgetown and South Park
This study tests whether reducing air pollution can help control asthma in children living in the Duwamish Valley. Kids with poorly controlled asthma who live in specified Seattle neighborhoods may benefit from cleaner air.
Seattle, WashingtonAges 6–17 - NCT06544811Recruiting
Smokefree Native: Smartphone quit support for American Indians
This trial tests a smartphone-based program to help American Indian adults quit smoking. If you are ready to try quitting and have daily access to a smartphone, you may be able to join for free support.
Minneapolis, MinnesotaAges 18 years+ - NCT06549231RecruitingPhase 3
Rituximab and mycophenolate for scleroderma lung disease
This trial tests whether combining two drugs, rituximab and mycophenolate mofetil, is safe and works better than standard care for lung scarring caused by scleroderma. It may be an option if your lung disease is severe or getting worse.
ToursAges 18–100 - NCT06465082Recruiting
Can diaphragm ultrasound predict successful breathing tube removal?
This trial uses ultrasound to measure how well your diaphragm (the main muscle you use to breathe) thickens when you breathe in. The goal is to see if this measurement can help doctors decide the best time to remove the breathing tube safely.
Al MansurahAges 18 years+ - NCT06471556RecruitingPhase 2
Steroid pulses for infant lung disease NEHI
This trial tests if giving methylprednisolone (a strong steroid) through an IV can help infants with a rare lung condition called NEHI. The goal is to see if it reduces oxygen needs and improves breathing.
ParisAges Up to 12 years - NCT06452797Recruiting
ICU Staff Predictions for Long-Term Ventilator Patients
This study asks ICU doctors, nurses, or other providers to give their best guess about what will happen to a patient who has been on a breathing machine for two weeks. The goal is to learn how healthcare teams think about recovery.
Chicago, IllinoisAges Any age - NCT06362980RecruitingPhase 1
BPI-1178 plus osimertinib for EGFR-mutated lung cancer
This trial tests a new drug (BPI-1178) combined with osimertinib for advanced lung cancer with EGFR mutations. It’s for people whose cancer has progressed after prior treatment with a third-generation EGFR targeted therapy.
BeijingAges 18 years+ - NCT06479252Recruiting
Comparing ways to test sit-to-stand in chronic lung disease
This study compares three ways of doing a simple sit-to-stand test for people with chronic lung disease: at the clinic, at home with video supervision, or on your own at home. The goal is to see which option works best and is easiest for patients.
Toronto, OntarioAges 18 years+ - NCT06419062Enrolling by invitation
Using wearables to monitor COPD at home
This study tests if a wearable device can help track your COPD symptoms between doctor visits. You'll use a smartphone or computer to share data, which may help your care team stay on top of your health.
GlasgowAges 18 years+ - NCT06438549Recruiting
Community health workers help pregnant smokers quit
This study tests whether adding a community health worker to your prenatal care team can help pregnant women quit smoking. It's for women who are ready to make a quit plan and are getting care at certain hospitals.
Loma Linda, CaliforniaAges 18 years+ - NCT06406777RecruitingPhase 1/Phase 2
MRI study of lung function after transplant
This study uses MRI scans to look at how well your lungs are working after a double lung transplant. It aims to understand chronic lung allograft dysfunction (CLAD), a condition that can affect transplant patients over time.
Iowa City, IowaAges 18–80 - NCT06476756Recruiting
Breathing exercises for recovery after heart surgery
This study tests two breathing techniques to help people recover after heart surgery where the breastbone was opened. The techniques may help you breathe easier and heal faster.
Lahore, Punjab ProvinceAges 40–60 - NCT06391424Recruiting
Oxygen use and breathing effort during ventilator weaning
If you are on a breathing machine in the ICU and ready to try breathing on your own, this study looks at how much oxygen your body uses during that test. It may help doctors better understand when you are ready to come off the ventilator.
Leiden, South HollandAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.