Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT00305305Recruiting
Brain development study for rare brain conditions
This study looks at how the brain develops in people with certain rare conditions that affect brain structure. It may help researchers understand these conditions better and could lead to improved care.
San Francisco, CaliforniaAges Any age - NCT05511363RecruitingPhase 3
Study of a new medicine for psychosis in Alzheimer's disease
This trial tests a new drug called KarXT to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease. If you or a loved one has Alzheimer's and experiences these symptoms, this study might offer a new treatment option.
Homewood, AlabamaAges 55–90 - NCT07768332Recruiting
Museum programs for autistic adults
This study tests three different museum-based programs to see how they affect autistic adults. It may help improve well-being and social connection through guided activities and group discussions.
TaipeiAges 18–50 - NCT06800053Recruiting
Support for LGBTQ+ cancer patients and caregivers
This study tests the FOCUS program, a support program designed for sexual and gender minority (LGBTQ+) cancer patients and their unpaid caregivers. It aims to help patients and caregivers cope with cancer through education and emotional support.
Detroit, MichiganAges 18–100 - NCT07567885Recruiting
Brief therapy to prevent suicide attempts in hospital
This study tests whether a short, focused therapy called Cognitive Behaviour Therapy can help prevent future suicide attempts in people admitted to a psychiatric hospital. You would receive this therapy while staying in the hospital after a recent suicide attempt or suicidal crisis.
StockholmAges 18 years+ - NCT07532460Recruiting
Study of brain channels and memory in cocaine users
This research explores how certain brain chemicals (potassium channels) affect memory and thinking in people who use cocaine regularly. The study may help develop better treatments for cocaine use disorder and related thinking problems.
Zurich, Canton of ZurichAges 20–50 - NCT07684417Recruiting
Sleep and attention in teens with ADHD
This study looks at how short or poorly timed sleep affects teens with ADHD. You will be asked to follow different sleep schedules and have your attention and body clock measured.
Cincinnati, OhioAges 13–17 - NCT07563517Recruiting
Peer coaching for substance use support in jail
This study tests whether connecting people in jail with peer coaches—people with lived experience of substance abuse recovery—can help them stay engaged with care after release. You'd receive support calls and guidance from someone who understands recovery firsthand.
Atlanta, GeorgiaAges 18 years+ - NCT07170553Recruiting
Relationship building digital game for caregivers and kids
This study tests a digital game designed to strengthen the bond between caregivers and children. It may help improve communication and connection in your relationship.
Coral Gables, FloridaAges 6 years+ - NCT07010705Recruiting
Digital measures for Huntington's disease trials
This study uses smartphone and wearable sensors to track movement and thinking in people with Huntington's disease. It aims to find better ways to measure how the disease progresses in clinical trials.
Rochester, New YorkAges 25–65 - NCT07161700Enrolling by invitationPhase 2
Long-term safety study of SPT-300 for major depression
This study is for people who finished the earlier BUOY-1 study of SPT-300 and want to continue treatment. It tests the long-term safety and tolerability of SPT-300 for major depressive disorder, with or without anxious distress.
Chino, CaliforniaAges 18–66 - NCT06804954Recruiting
Online CBT vs. usual care for mild mental health issues
This study tests an online CBT program (cognitive behavioral therapy you do from home) versus usual care for people with mild to moderate anxiety, depression, or stress. It aims to help you manage symptoms before they become more serious.
Gustavsberg, Stockholm CountyAges 18 years+ - NCT07087951Recruiting
Sound therapy for memory loss in older adults
This study tests whether listening to a special sound (gamma-frequency tones) can help slow down memory loss in older adults. It's for people who have mild memory problems but not dementia or other brain disorders.
Taoyuan, GuishanAges 60 years+ - NCT07066826RecruitingPhase 2/Phase 3
Huperzine A for mild-to-moderate Alzheimer's dementia
This study tests whether Huperzine A controlled-release tablets can help improve memory and thinking in people with mild-to-moderate Alzheimer's disease. You'll take the tablets or a placebo to see if it slows down dementia symptoms.
BeijingAges 50–85 - NCT05825820Recruiting
Phone-based outreach to help prevent future suicide attempts
This pilot study tests a health care and community outreach program that contacts people after an Emergency Department (ED) visit to help prevent suicide attempts. You may get follow-up support through partners like Samaritans of Boston using phone, text, or email.
Boston, MassachusettsAges 18 years+ - NCT07185451Recruiting
Brain stimulation for teens with depression
This trial tests if a gentle electrical brain stimulation called tACS can help teens with depression who are already on stable medication. The treatment is added to their usual medication to see if it improves mood.
Chongqing, Chongqing MunicipalityAges 12–18 - NCT07006935Recruiting
Clubhouse program effects on recovery and brain health
This study looks at how Clubhouse programs (a type of community-based support) affect thinking and brain health in people with schizophrenia or related conditions. It compares Clubhouse participation to usual care. If eligible, you would complete thinking tests and possibly an MRI brain scan.
Cleveland, OhioAges 18–50 - NCT06804941Recruiting
Online CBT vs. usual care for common mental health issues
This study tests whether online cognitive behavioral therapy (CBT) works better than usual care for people with common mental health issues like anxiety, depression, or stress. If eligible, you would receive a guided online program from your computer or phone, without needing to visit a clinic.
Gustavsberg, Stockholm CountyAges 18 years+ - NCT07065240RecruitingPhase 2
Study of SPT-300 for major depression with or without anxiety
This trial tests an experimental oral medication, SPT-300, for people with major depressive disorder, even if they also have mild anxiety. The goal is to see if it helps improve mood safely.
Chino, CaliforniaAges 18–65 - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT07752784RecruitingPhase 3
Tau brain imaging in people with mild thinking changes or Alzheimer's
This study uses a special PET scan to take pictures of abnormal tau protein in the brain. It aims to see if the scan results match what is found in brain tissue after death, which could help improve diagnosis of Alzheimer's and related conditions.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05294042Recruiting
Patient navigators for children’s mental health care
This study tests a support program that helps children and caregivers find and get community mental health services, especially in high-poverty areas. It may help by making it easier to connect with the right services and stay engaged while waiting or starting care.
Chicago, IllinoisAges Up to 14 years - NCT07169747RecruitingPhase 2
Psilocybin with therapy for young adults with anorexia
This study tests two different doses of psilocybin, a substance that may help change thinking patterns, given alongside psychological support to young adults with anorexia nervosa. It aims to see if it is safe and helpful for weight recovery and mental health.
LundAges 16–35 - NCT07766161Recruiting
Light therapy for postpartum depression
This trial tests whether timed light therapy can improve postpartum depression symptoms. It focuses on new mothers within six months of giving birth who have elevated depression scores.
Ann Arbor, MichiganAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.