Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT07761546Enrolling by invitation
Ai-test: microbiome nutrition for low testosterone
This study tests whether a special diet can improve symptoms of low testosterone in men. It is intended to help men with certain symptoms like a low sex drive or trouble having erections and whose blood tests show low to borderline testosterone levels.
AydinAges 30–65 - NCT07359157Recruiting
Support program for WRCH patients with legal history
This study offers a group program at Worcester Recovery Center and Hospital (WRCH) aimed at helping people who have been involved with the legal system. It is designed for current patients at WRCH who are at least 18 years old and comfortable speaking English.
Worcester, MassachusettsAges 18 years+ - NCT07434895RecruitingEarly Phase 1
Can CBD Change How You Use Cannabis?
This study looks at how taking CBD (a cannabis compound that doesn't get you high) affects your cannabis use. It is for healthy adults who use cannabis for recreational reasons, not for medical treatment.
Lexington, KentuckyAges 18–55 - NCT07217665Enrolling by invitationPhase 2
AADvac1 vaccine for progressive supranuclear palsy
This trial tests a vaccine called AADvac1 for people with progressive supranuclear palsy (PSP), a brain condition that affects movement and thinking. The study wants to see if the vaccine can slow the disease down.
San Francisco, CaliforniaAges 41–86 - NCT05142384Recruiting
Online therapy program for mothers with depression symptoms
This study tests an internet-based cognitive behavioral therapy (an online skills-based talk therapy) to help mothers with depression symptoms. It’s offered through Head Start, where participating moms and their children connect with the program.
Springfield, OregonAges 2 years+ - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT06584448Recruiting
Drinking, acetate, and stress study
This study looks at how acetate (a substance produced when the body breaks down alcohol) affects stress and drinking. It tests if giving acetate can help people with alcohol use disorder (AUD) reduce their drinking.
New Haven, ConnecticutAges 18–60 - NCT05725239Recruiting
Testing vibration or magnetic stimulation for depression
This study tests whether taVNS, TMS, or both can improve depression symptoms. It may help people whose depression has not improved enough with usual treatments like antidepressant pills or talking therapy.
Charleston, South CarolinaAges 18–75 - NCT06349083RecruitingPhase 2
Psilocybin-assisted treatment for alcohol use disorder
This study tests whether psilocybin, a psychedelic drug, combined with therapy can help people reduce or stop drinking. It aims to understand how psilocybin affects the brain and behavior in people with alcohol use disorder.
New York, New YorkAges 18–65 - NCT07756723RecruitingPhase 2/Phase 3
Comparing PTSD treatments for veterans with substance use
This study compares two proven treatments for veterans who have both PTSD and substance use problems. It aims to find which treatment works best to help with trauma recovery.
Coatesville, PennsylvaniaAges 18 years+ - NCT07757997Recruiting
Recovery and work after stress treatment
This study checks how people who completed a hospital program for stress-related issues are doing over time, focusing on their health and ability to work. It aims to understand the long-term effects of the treatment.
SüsAges 18–80 - NCT04556890Recruiting
Brain stimulation for treatment-resistant depression and chronic pain
This study tests a non-invasive brain stimulation treatment, called transcranial magnetic stimulation (TMS), to see if it can help people who have both major depression that hasn't improved with medication and chronic pain from fibromyalgia or chronic fatigue syndrome. It aims to reduce both depression and pain symptoms.
Los Angeles, CaliforniaAges 18–75 - NCT04870255Recruiting
Brain stimulation for depression in borderline personality disorder
This study tests a type of brain stimulation called rTMS to see if it can help improve mood in people who have both depression and borderline personality disorder. It may offer a new treatment option for those who haven't tried TMS before.
Stanford, CaliforniaAges 18–80 - NCT07757542RecruitingPhase 2
Hydrogen gas for mild cognitive impairment
This trial tests whether breathing in a small amount of hydrogen gas is safe and might help people with mild cognitive impairment. It aims to see if this simple approach could support brain health.
Ostrava, Moravian-Silesian RegionAges 50–80 - NCT06651177RecruitingPhase 2
Tirzepatide with buprenorphine for opioid use disorder
This study tests whether adding tirzepatide, a medication used for weight and blood sugar, to buprenorphine treatment helps people with opioid use disorder. It aims to see if the combination improves outcomes compared to buprenorphine alone.
Jacksonville, FloridaAges 18 years+ - NCT06781801Recruiting
Heart and metabolic health for severe mental illness
This trial tests a long-term program to improve heart and metabolic health in adults with schizophrenia or related disorders. It may help reduce health risks often linked with severe mental illness.
GothenburgAges 18 years+ - NCT07218354RecruitingPhase 3
Medication for reducing alcohol use in veterans
This study tests whether a medication (semaglutide) can help veterans reduce or stop drinking alcohol. It is for veterans who drink heavily and have alcohol use disorder, and who are interested in cutting down.
Long Beach, CaliforniaAges 18–80 - NCT07757763Recruiting
Slow jogging for breast cancer survivors
This study looks at whether slow jogging (a gentle form of running) can help breast cancer survivors sleep better. You'll be asked to use a smartphone app to track your activity and sleep, and you may be assigned to a jogging group or a usual-care group.
Taipei, Taipei CityAges 20 years+ - NCT07757178Recruiting
Dementia lived experiences study
This study explores the personal stories and experiences of people with dementia, their families, and caregivers to help improve care and support. Participation involves sharing your experiences in interviews or other tasks.
Nottingham, EnglandAges 18–99 - NCT07551934Recruiting
Women's Mental Health and Pregnancy Choices in Wartime Ukraine
This study looks at how pregnant women and new mothers in Ukraine are coping emotionally and making decisions about their pregnancies and babies during wartime. Researchers want to understand your experiences to help improve support for women in similar situations.
KyivAges 18 years+ - NCT06911112RecruitingPhase 3
A new pill for depression when current treatment isn't working well enough
This trial tests an investigational medication (NBI-1065845) added to your current antidepressant to see if it can improve depressive symptoms. It is for people with moderate to severe depression who have not fully responded to their current antidepressant.
Huntsville, AlabamaAges 18 years+ - NCT07177261Recruiting
Brain synchrony study for schizophrenia
This study looks at how brain activity syncs between people with schizophrenia and others. It aims to understand social interaction differences—potentially leading to better treatments.
Los Angeles, CaliforniaAges 18–65 - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT04957537Recruiting
Speech and meaning therapy for primary progressive semantic aphasia
This study tests a “semantic rehabilitation” program—therapy focused on improving word meaning and understanding—for people with primary progressive semantic aphasia. If you qualify, it may help slow or improve language difficulties and daily communication.
ToulouseAges 18–100
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.