Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT06103760RecruitingPhase 4
Esketamine for hard-to-treat depression
This study tests whether esketamine, a nasal spray for depression, can help adults whose depression has not improved with at least two other antidepressants. Participants continue their current treatment while receiving esketamine.
St Leonards, New South WalesAges 18–65 - NCT05675735Recruiting
Methadone take-home program to help people stay in treatment
This trial studies whether changing how methadone is allowed to be taken home can improve how long people stay in opioid use disorder treatment. It focuses on clinics and on adults who have already been receiving take-home methadone.
Storrs, ConnecticutAges 18 years+ - NCT06710483Recruiting
Dental care help for youth with disabilities
This study aims to make dental visits easier for youth with intellectual or developmental disabilities. It tests a program to support both patients and their dental providers.
Boston, MassachusettsAges 12–18 - NCT07610473RecruitingPhase 2
Testing DT-101 as an add-on for depression
This trial tests if a new medication, DT-101, can help when added to your current depression treatment. It's for adults with recurrent depression who may need extra support.
Phoenix, ArizonaAges 18–75 - NCT07046819RecruitingPhase 2
Tirzepatide for liver disease linked to alcohol use
This trial tests if tirzepatide, a medication that helps with weight and blood sugar, can improve liver health in people with alcohol use disorder who also have fatty liver disease. It aims to reduce liver fat and related risks.
Bethesda, MarylandAges 21–100 - NCT07603518RecruitingPhase 1
How a Hemp Topical Product Works in Your Body
This Johns Hopkins study tests a hemp-based cream to understand how your body absorbs and processes it. You'll stay overnight in the clinic and let researchers measure the product's effects, which could help develop better cannabis-based treatments.
Baltimore, MarylandAges 18–55 - NCT06203509Recruiting
Helping after a hospital stay for serious mental illness
This study helps people with serious mental illness who are on Medicaid, living in Pennsylvania, and recently left the hospital. It offers extra support and care in your home to make the transition smoother.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07575178Recruiting
Movement Training for Children With Coordination Difficulties
This study compares two types of movement training—obstacle courses versus targeted coordination exercises—for children ages 7–10 who have difficulty with coordination and motor skills. The goal is to see which approach helps children move and balance better.
Lahore, Punjab ProvinceAges 7–10 - NCT07434271RecruitingPhase 2
KH-001 for Lifelong Premature Ejaculation
This trial tests an investigational drug called KH-001 to see if it can help men with lifelong premature ejaculation last longer during intercourse. It focuses on men who consistently ejaculate very quickly (within a minute) and are in a stable relationship.
Botany, New South WalesAges 18–65 - NCT07462637Recruiting
Light therapy for depression in unipolar and bipolar disorder
This study tests how well light therapy works for moderate to severe depression in people with or without bipolar disorder. It includes a possible MRI brain scan to understand how light affects the brain. You must not have certain eye conditions or high suicide risk.
ParisAges 18–65 - NCT05302583Recruiting
Aromatherapy inhaler for stress during stem cell transplant
This trial tests whether using a lavender or peppermint aromatherapy inhaler can reduce distress (stress or discomfort) for adults during stem cell transplant care. It’s for people who are getting chemotherapy before the transplant and who do not have allergies to those essential oils.
Stanford, CaliforniaAges 18 years+ - NCT07456579Enrolling by invitation
Alcohol and cannabis use in pregnancy
This study looks at alcohol and cannabis use during pregnancy by asking new mothers about their habits and testing newborn stool samples (meconium). The goal is to understand how common these substances are among pregnant women in Slovenia and how they might affect babies.
LjubljanaAges Any age - NCT07613710RecruitingPhase 1
Safety study of Lu AH69593 for healthy adults or narcolepsy
This study tests whether a new medication called Lu AH69593 is safe and well-tolerated in healthy adults and people with narcolepsy type 1. Researchers want to understand how the drug affects the body and whether it could help treat excessive daytime sleepiness.
HelsinkiAges 18–64 - NCT07120880RecruitingPhase 3
Light therapy timing for depression with insomnia
This trial tests whether giving light therapy at a specific time of day can improve both depression and sleep problems. It is for adults with major depression and insomnia who are not currently on antidepressants.
ParisAges 18–65 - NCT04519229Enrolling by invitation
Feasibility study of child-parent therapy for foster infants and toddlers
This study tests whether a therapy program called Child-Parent Psychotherapy is practical and helpful for very young children in foster care and the adults caring for them. It’s mainly a “feasibility” study, meaning it focuses on whether the program can be delivered and followed in real life.
VaxjoAges birth–6 years - NCT02300766Recruiting
Study of cerebellar mutism in children with brain tumors
This study looks at how children with certain brain tumors develop “cerebellar mutism” after surgery or an open biopsy. The goal is to better understand the syndrome and what might help support recovery.
ViennaAges Up to 18 years - NCT07264283Enrolling by invitationPhase 2
Testing LM11A-31 for progressive supranuclear palsy
This trial tests a drug called LM11A-31 to see if it can help people with progressive supranuclear palsy (PSP), a rare brain condition. You may join if you have had symptoms for 5 years or less, can walk with minimal help, and have good thinking abilities.
San Francisco, CaliforniaAges 41–86 - NCT06908226Enrolling by invitationPhase 3
LP352 for children and adults with DEE
This trial tests a medication called LP352 for children and adults with certain types of epilepsy (Dravet syndrome, Lennox-Gastaut syndrome, or other developmental and epileptic encephalopathies). It's for people who already completed a previous study of LP352 and may benefit from continued treatment.
Little Rock, ArkansasAges 2–66 - NCT07348666Recruiting
Smartphone safety planning for teens at risk
This trial tests a smartphone-based safety planning tool that gives you support right when you need it. It's designed for teens and young adults who are at risk for suicide and are already getting care at participating clinics.
Eugene, OregonAges 13–24 - NCT04732052Recruiting
tDCS treatment for adults with developmental disabilities and aggression
This trial tests whether a non-painful brain stimulation treatment (tDCS) can reduce aggressive behaviors in adults with developmental disabilities. It’s meant for people who have had aggression in the last month and can safely receive the stimulation.
Kingston, OntarioAges 18–65 - NCT07370311Recruiting
Support for Chinese American dementia caregivers on feeding choices
This study tests a decision aid designed to help Chinese American caregivers of older adults with dementia make feeding-related choices, especially near the end of life. It aims to support you in decisions about feeding options.
Austin, TexasAges 21–99 - NCT07408934Enrolling by invitation
Group therapy for feeling safer with psychosis
This trial tests a group therapy program called the Feeling Safe Programme for people with psychosis. It aims to help you learn new ways to cope with your symptoms and feel safer. It meets once a week for 75 minutes.
Ottawa, OntarioAges 18 years+ - NCT06969170RecruitingPhase 2
Psilocybin oral solution for generalized anxiety disorder trial
This study tests a psilocybin oral solution in adults with generalized anxiety disorder (GAD). It aims to see if the drug is safe, tolerable, and helpful for reducing anxiety symptoms.
Kingston, OntarioAges 18–60
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.