Clinical trials
Apnea clinical trials
Below are recruiting apnea clinical trials, each written for real people, not researchers. We’re tracking 351 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06043440RecruitingPhase 2
Oxygen therapy for sleep apnea in Down syndrome
This study tests whether oxygen therapy can help children with Down syndrome who have sleep apnea. It compares oxygen treatment to no treatment to see if it improves breathing during sleep and thinking skills.
Los Angeles, CaliforniaAges 5–18 - NCT05953610RecruitingPhase 2
Surgery study for sleep apnea when CPAP won’t work
This Phase 2 trial tests whether a specific type of palate surgery can treat moderate-to-severe obstructive sleep apnea in people who cannot tolerate CPAP (a breathing mask). It also checks patient traits (based on sleep testing) to see who is most likely to benefit from surgery.
Santa Monica, CaliforniaAges 21 years+ - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75 - NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT05612594RecruitingPhase 4
Study of an SGLT2 pill for sleep apnea in overweight adults
This study tests whether taking an SGLT2 inhibitor pill (bexagliflozin) can improve obstructive sleep apnea and related body measurements. It focuses on people who are overweight or obese and have confirmed obstructive sleep apnea.
New Haven, ConnecticutAges 18 years+ - NCT05575401Recruiting
Track surgery results in kids getting tonsil removal
This trial looks at how well a specific throat surgery technique works in children who are having their tonsils removed (with or without removing adenoids). It may help improve how doctors choose and perform surgery for safer, better recovery.
Murrieta, CaliforniaAges 3–17 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05497180RecruitingPhase 1
Testing an oral device to reduce snoring and mild sleep apnea
This Phase 1 study tests whether a passive mouth/oral appliance can lessen snoring and mild obstructive sleep apnea. It may help you by improving airflow during sleep without other intensive treatments.
Edmonton, AlbertaAges 18 years+ - NCT05459935Recruiting
Light treatment for enlarged tonsils in children
This trial studies whether a light-based treatment (called photobiomodulation) can help children with very enlarged tonsils. It may improve breathing and sleep symptoms, and you’d have before-and-after checkups, including sleep testing.
Edmonton, AlbertaAges 6–12 - NCT05303987RecruitingPhase 2
Dexmedetomidine or propofol for sleep endoscopy in children
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Ann Arbor, MichiganAges 3–11 - NCT05289063RecruitingPhase 1
Study new sleep apnea and blood vessel function
This Phase 1 study looks at how blood vessel function is affected by obstructive sleep apnea in adults who are newly diagnosed and have not used CPAP. It may help researchers understand the early effects of sleep apnea and guide future treatments.
New York, New YorkAges 18 years+ - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05052216Recruiting
Wearable monitor study for kids’ sleep apnea
This study tests a wearable device that can help monitor breathing and sleep in children. It compares children with sleep apnea to children without sleep apnea using a simple nighttime monitoring approach.
Bethesda, MarylandAges 3–12 - NCT04991389RecruitingPhase 4
Test a breathing study plan for kids with sleep apnea after surgery
This trial studies how to improve outcomes for children who still have obstructive sleep apnea after having their tonsils and adenoids removed. It uses computer modeling (based on breathing/airflow) and may include a special breathing gas during testing in some parts of the study.
Cincinnati, OhioAges 3–18 - NCT04905238Enrolling by invitation
Sleep apnea study linking breathing markers to memory changes
This trial looks at how severe sleep apnea breathing patterns relate to body “biomarkers” linked to Alzheimer’s disease, using blood or other measures. It may help researchers understand whether sleep apnea is connected to memory and brain health—and who might benefit most from better sleep care.
Palma, Balearic IslandsAges 18–65 - NCT03109171Recruiting
Test accuracy using a scope-based feeling test for sleep apnea
This study checks how accurately a special camera/scope test can measure throat sensation in people being evaluated for obstructive sleep apnea (OSA). If the test works well, it may help improve how clinicians understand and assess OSA-related changes.
Bogotá, Bogota D.C.Ages 18 years+ - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT04603196Recruiting
Study sleep apnea in adults with multiple sclerosis
This study looks at how often sleep apnea happens in people who have multiple sclerosis, and how it affects daily life and health. You may be invited to participate if you’re an adult with a confirmed multiple sclerosis diagnosis and can consent to the study.
Boston, MassachusettsAges 18 years+ - NCT04471740Recruiting
Study of hydrocephalus and sleep apnea
This study looks at people who may have normal-pressure hydrocephalus (fluid-related swelling in the brain) and also focuses on sleep apnea. It may help researchers understand whether treating or studying sleep issues could improve symptoms related to this condition.
Valencia, ValenciaAges 18 years+ - NCT04186078Recruiting
Study symptoms and traits of sleep apnea in Korea
This study looks at people in Korea who may have sleep apnea based on common symptoms. The goal is to better understand who has sleep apnea and how it shows up, which may help improve future diagnosis and care.
SeoulAges 19 years+ - NCT04124848Recruiting
Sleep apnea study for Somali community adults
This study looks at obstructive sleep apnea—breathing pauses or poor breathing during sleep—in Somali community members. It aims to learn more about sleep apnea in this specific group, which can help guide better care.
Rochester, MinnesotaAges 18 years+
Hear when a new Apnea trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for apnea?
- Yes. Clin2 currently lists 351 recruiting apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.