Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 549 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT03718364Recruiting
Atrial fibrillation ablation registry study in Switzerland
This study records information from people undergoing a procedure to treat atrial fibrillation called pulmonary vein isolation. It helps doctors understand how the procedure is used and what outcomes to expect.
BaselAges 18 years+ - NCT04267159Recruiting
Treatment plan for sudden irregular heartbeat in the ER
This trial looks at how to manage a new, sudden irregular heartbeat (atrial fibrillation or atrial flutter) when you first arrive in the emergency room. It may help by testing an “elective” approach to rhythm control, depending on your heart rate and overall safety factors.
Jyväskylä, Central FinlandAges Any age - NCT04593498Recruiting
Test for abnormal heart rhythm triggers for some heart rhythm types
This study looks at people who have frequent abnormal signals from the upper heart (supraventricular extra beats or short runs) and how that relates to atrial fibrillation risk. If you qualify, you may help researchers understand better ways to prevent or manage certain heart rhythm problems.
StockholmAges 70–89 - NCT04642430RecruitingPhase 4
Test of blood thinners comparing rivaroxaban vs apixaban
This trial compares the bleeding risk of two commonly used blood thinners—rivaroxaban and apixaban—in people with atrial fibrillation (AF). If you’re starting an anticoagulant for a new AF diagnosis, this may help doctors choose the safer option for you and others.
Victoria, British ColumbiaAges 18 years+ - NCT04696081Recruiting
Atrial fibrillation treatment in people with active cancer
This trial studies atrial fibrillation (an irregular heartbeat) in adults who have active cancer. It looks at people whose atrial fibrillation started after their cancer diagnosis or returned after cancer diagnosis.
Caen, NormandyAges 18 years+ - NCT04700826RecruitingPhase 4
Preventing stroke, death, and memory decline in atrial fibrillation
This trial looks at ways to help people with atrial fibrillation lower their risk of stroke, premature death, and worsening memory. It may help by identifying which prevention approach works best for a broader community of patients.
Birmingham, West MidlandsAges 55–73 - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT04776759Recruiting
Study of first atrial fibrillation in young adults
This study records and follows people under 35 who have their first episode of an irregular heartbeat. It aims to better understand this condition early on and how it shows up in real life.
Caen, NormandyAges Up to 35 years - NCT07523620Recruiting
Heart rhythm procedure with left atrial appendage closure
This trial tests a procedure that closes off a small pouch in the heart (left atrial appendage) while also treating irregular heartbeat (atrial fibrillation) with a catheter ablation procedure. The goal is to reduce your stroke risk and treat your symptoms without needing blood thinners long-term.
Brussels, B CAP RAges 18 years+ - NCT04997824Recruiting
AI-guided selection for atrial fibrillation ablation
This trial tests whether an artificial intelligence (AI) system can help choose the best patients for a procedure called catheter ablation for atrial fibrillation (AF). It may improve which people benefit most while keeping safety in mind.
SeoulAges Any age - NCT05009797Recruiting
Study follow-up after catheter ablation for atrial fibrillation
This trial is looking at what happens after a heart procedure called catheter ablation for atrial fibrillation (an irregular heartbeat). It mainly collects follow-up outcomes to better understand recovery and results for patients.
LilleAges 18 years+ - NCT05014802Recruiting
MRI scans before heart surgery to predict post-surgery atrial fibrillation
This study uses an MRI scan before heart surgery to look for heart scarring that may predict who will develop atrial fibrillation afterward. Knowing the risk ahead of time could help doctors monitor you more closely and plan prevention.
Covington, LouisianaAges 40–120 - NCT05021601Recruiting
Ablation method comparison for rheumatic valve and ongoing AF
This study compares two heart procedures—targeting one or both upper heart chambers versus only the left upper chamber—to treat people with ongoing atrial fibrillation caused by rheumatic mitral valve disease. It aims to see which approach works better and is safer for restoring normal rhythm.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05044208Recruiting
Test heart ultrasound and monitoring clues for atrial fibrillation
This study looks at heart ultrasound pictures and heart-rhythm recordings to predict who may develop atrial fibrillation (AF) after a stroke or TIA. If you qualify, your results may help doctors better spot people at higher risk earlier.
TullnAges 18 years+ - NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT05144503Recruiting
Test of a new catheter procedure for irregular heart rhythm
This study checks how safe and effective a special catheter procedure (SpherePVI) is for treating paroxysmal (comes and goes) or persistent atrial fibrillation. You may be considered if your atrial fibrillation keeps returning and you’ve already tried at least one medication but it didn’t work or you couldn’t tolerate it.
VilniusAges 18–75 - NCT05164107Recruiting
Test a new pulsed-field catheter procedure for atrial fibrillation
This trial tests a new pulsed-field device used during an atrial fibrillation (AF) catheter ablation, aiming to improve safety and effectiveness. It’s for people who have AF and are planning an AF ablation procedure.
PragueAges 18–75 - NCT05266144Recruiting
Catheter ablation for non-valvular atrial fibrillation
This trial studies catheter ablation, a procedure that targets heart rhythm triggers, for people with atrial fibrillation (an irregular heartbeat). It may help improve rhythm control, but you must meet specific heart and testing requirements and avoid certain conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05311137Recruiting
Closed-loop monitoring for atrial fibrillation
This study tests a “closed-loop” approach to treating atrial fibrillation, meaning the care plan may adjust based on how you’re doing. It may help improve how heart rhythm problems are managed over time.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT05332457Recruiting
Beta-blocker effects on heart rate and exercise capacity in atrial fibrillation
This study looks at how taking a beta-blocker affects your resting heart rate during activity and how fit your heart and lungs are during an exercise test. It may help clarify whether the way the medication controls heart rate is linked to better exercise tolerance in people with persistent atrial fibrillation.
TaipeiAges 20 years+ - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 549 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.